EA202092283A1 - ANTIBODY CONSTRUCTS TO CDH19 AND CD3 - Google Patents
ANTIBODY CONSTRUCTS TO CDH19 AND CD3Info
- Publication number
- EA202092283A1 EA202092283A1 EA202092283A EA202092283A EA202092283A1 EA 202092283 A1 EA202092283 A1 EA 202092283A1 EA 202092283 A EA202092283 A EA 202092283A EA 202092283 A EA202092283 A EA 202092283A EA 202092283 A1 EA202092283 A1 EA 202092283A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- antibody construct
- cdh19
- relates
- human
- binding
- Prior art date
Links
Landscapes
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
Изобретение относится к конструкции антитела, содержащей первый связывающий домен человека, способный связываться с CDH19 человека на поверхности клетки-мишени, и второй домен, способный связываться с CD3 человека на поверхности Т-клетки. Более того, изобретение относится к последовательности нуклеиновой кислоты, кодирующей конструкцию антитела, вектору, содержащему указанную последовательность нуклеиновой кислоты, и к клетке-хозяину, трансформированной или трансфицированной указанным вектором. Более того, изобретение относится к способу получения конструкции антитела, к медицинскому применению указанной конструкции антитела и к набору, содержащему указанную конструкцию антитела.The invention relates to an antibody construct comprising a first human binding domain capable of binding to human CDH19 on the surface of a target cell and a second domain capable of binding to human CD3 on the surface of a T cell. Moreover, the invention relates to a nucleic acid sequence encoding an antibody construct, a vector containing said nucleic acid sequence, and a host cell transformed or transfected with said vector. Moreover, the invention relates to a method for producing an antibody construct, to the medical use of said antibody construct, and to a kit containing said antibody construct.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361785147P | 2013-03-14 | 2013-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA202092283A1 true EA202092283A1 (en) | 2022-01-31 |
Family
ID=80631247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA202092283A EA202092283A1 (en) | 2013-03-14 | 2014-01-27 | ANTIBODY CONSTRUCTS TO CDH19 AND CD3 |
Country Status (1)
| Country | Link |
|---|---|
| EA (1) | EA202092283A1 (en) |
-
2014
- 2014-01-27 EA EA202092283A patent/EA202092283A1/en unknown
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