EA201990934A1 - TRICYCLIC COMPOUNDS OF BENZOXABOROL AND THEIR APPLICATION - Google Patents
TRICYCLIC COMPOUNDS OF BENZOXABOROL AND THEIR APPLICATIONInfo
- Publication number
- EA201990934A1 EA201990934A1 EA201990934A EA201990934A EA201990934A1 EA 201990934 A1 EA201990934 A1 EA 201990934A1 EA 201990934 A EA201990934 A EA 201990934A EA 201990934 A EA201990934 A EA 201990934A EA 201990934 A1 EA201990934 A1 EA 201990934A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- benzoxaborol
- application
- tricyclic compounds
- compounds
- chchch
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Предложены соединения формулы II, где X выбран из хлора, фтора, брома и йода, каждый из Rи Rнезависимо выбран из H, -CH, -CHCH, -CHCHCHили -CH(CH); композиции, содержащие их; их применение в терапии, включая их применение в качестве антимикобактериальных агентов, например в лечении микобактериальной инфекции у млекопитающего; и способы получения таких соединений.Compounds of formula II are provided, where X is selected from chlorine, fluorine, bromine and iodine, each of R and R is independently selected from H, —CH, —CHCH, —CHCHCH, or —CH (CH); compositions containing them; their use in therapy, including their use as antimycobacterial agents, for example, in the treatment of mycobacterial infection in a mammal; and methods for preparing such compounds.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361918976P | 2013-12-20 | 2013-12-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201990934A1 true EA201990934A1 (en) | 2020-01-31 |
| EA038093B1 EA038093B1 (en) | 2021-07-05 |
Family
ID=69374499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201990934A EA038093B1 (en) | 2013-12-20 | 2014-08-08 | METHOD OF TREATING A DISEASE CAUSED BY A MYCOBACTERIUM TUBERCULOSIS COMPLEX INFECTION USING (S)-(3-CHLORO-7,8-DIHYDRO-2H-1,6,9-TRIOXA-9a-BORABENZO[cd]AZULEN-2-YL)METHANAMINE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF |
Country Status (1)
| Country | Link |
|---|---|
| EA (1) | EA038093B1 (en) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3396B1 (en) * | 2007-06-20 | 2019-10-20 | Anacor Pharmaceuticals Inc | Boron-containing small molecules |
| BR112012024682B1 (en) * | 2010-04-07 | 2021-06-08 | Glaxosmithkline Llc | processes to contact, to manufacture and to form a compound as well as a compound |
| CA2810021C (en) * | 2010-09-07 | 2018-05-29 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules |
| EP2793901A1 (en) * | 2011-12-22 | 2014-10-29 | Micurx Pharmaceuticals, Inc. | Tricyclic boron compounds for antimicrobial therapy |
-
2014
- 2014-08-08 EA EA201990934A patent/EA038093B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EA038093B1 (en) | 2021-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG TJ TM |