EA201791099A1 - Хинолин карбоксамиды для применения в лечении лейкоза - Google Patents

Хинолин карбоксамиды для применения в лечении лейкоза

Info

Publication number
EA201791099A1
EA201791099A1 EA201791099A EA201791099A EA201791099A1 EA 201791099 A1 EA201791099 A1 EA 201791099A1 EA 201791099 A EA201791099 A EA 201791099A EA 201791099 A EA201791099 A EA 201791099A EA 201791099 A1 EA201791099 A1 EA 201791099A1
Authority
EA
Eurasian Patent Office
Prior art keywords
leukemia
treatment
quinolin
carboxamide
quinolin carboxamide
Prior art date
Application number
EA201791099A
Other languages
English (en)
Other versions
EA031643B1 (ru
Inventor
Хелена Эрикссон
Лейф Свенсон
Мари Торнгрен
Original Assignee
Эктив Байотек Аб
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эктив Байотек Аб filed Critical Эктив Байотек Аб
Publication of EA201791099A1 publication Critical patent/EA201791099A1/ru
Publication of EA031643B1 publication Critical patent/EA031643B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Abstract

Соединение формулы (I)или его фармацевтически приемлемая соль для применения в лечении лейкоза.
EA201791099A 2014-11-19 2015-11-05 Применение тасквинимода для лечения острого лимфобластного лейкоза и острого миелоидного лейкоза EA031643B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14193776 2014-11-19
PCT/EP2015/075769 WO2016078921A1 (en) 2014-11-19 2015-11-05 Quinoline carboxamides for use in the treatment of leukemia

Publications (2)

Publication Number Publication Date
EA201791099A1 true EA201791099A1 (ru) 2017-10-31
EA031643B1 EA031643B1 (ru) 2019-01-31

Family

ID=51951635

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201791099A EA031643B1 (ru) 2014-11-19 2015-11-05 Применение тасквинимода для лечения острого лимфобластного лейкоза и острого миелоидного лейкоза

Country Status (15)

Country Link
US (1) US10300053B2 (ru)
EP (1) EP3180005B1 (ru)
JP (1) JP6715833B2 (ru)
KR (1) KR102525805B1 (ru)
CN (1) CN107072989B (ru)
AU (1) AU2015348778B2 (ru)
BR (1) BR112017009854B1 (ru)
CA (1) CA2967112C (ru)
EA (1) EA031643B1 (ru)
ES (1) ES2663836T3 (ru)
IL (1) IL252174B (ru)
MX (1) MX2017006110A (ru)
NZ (1) NZ732704A (ru)
PL (1) PL3180005T3 (ru)
WO (1) WO2016078921A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021229611A1 (en) 2020-03-03 2022-10-27 Active Biotech Ab Tasquinimod or a pharmaceutically acceptable salt thereof for use in combination therapy
IL300068A (en) 2020-07-23 2023-03-01 Univ Erasmus Med Ct Rotterdam S100 proteins as new therapeutic targets in myeloproliferative catalysis
KR20230133317A (ko) 2021-01-18 2023-09-19 액티브 바이오테크 에이비 골수이형성 증후군의 치료에 이용하기 위한 타스퀴니모드또는 이의 약제학적으로 허용가능한 염
CN117295492A (zh) 2021-05-25 2023-12-26 活跃生物技术有限公司 多个他喹莫德粒子及其用途
KR20240029029A (ko) 2021-07-02 2024-03-05 액티브 바이오테크 에이비 타스퀴니모드를 함유한 약학적 제품 및 이러한 제품의 순도 평가 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801474D0 (sv) 1998-04-27 1998-04-27 Active Biotech Ab Quinoline Derivatives
SE9802549D0 (sv) 1998-07-15 1998-07-15 Active Biotech Ab Quinoline derivatives
SE0002320D0 (sv) * 1999-10-25 2000-06-21 Active Biotech Ab Malignant tumors
SE0201778D0 (sv) 2002-06-12 2002-06-12 Active Biotech Ab Process for the manufacture of quinoline derivatives
SE0400235D0 (sv) 2004-02-06 2004-02-06 Active Biotech Ab New composition containing quinoline compounds
CA2802006C (en) 2010-07-09 2018-09-25 Active Biotech Ab Method for manufacturing of quinoline-3-carboxamides
EP2537517A1 (en) * 2011-06-22 2012-12-26 Active Biotech AB Deuterium-enriched 4-hydroxy-5-methoxy-n,1-dimethyl-2-oxo-n-[(4-trifluoro-methyl)phenyl]-1,2-dihydroquinoline-3-carboxamide
WO2015095833A1 (en) * 2013-12-20 2015-06-25 Biomed Valley Discoveries, Inc. Treatment of hematologic cancers

Also Published As

Publication number Publication date
BR112017009854B1 (pt) 2022-08-23
BR112017009854A2 (pt) 2018-01-16
MX2017006110A (es) 2017-07-27
EA031643B1 (ru) 2019-01-31
WO2016078921A1 (en) 2016-05-26
CN107072989B (zh) 2020-07-03
CA2967112A1 (en) 2016-05-26
EP3180005A1 (en) 2017-06-21
JP6715833B2 (ja) 2020-07-01
JP2017534652A (ja) 2017-11-24
EP3180005B1 (en) 2017-12-27
IL252174A0 (en) 2017-07-31
KR102525805B1 (ko) 2023-04-25
AU2015348778A1 (en) 2017-06-29
US10300053B2 (en) 2019-05-28
KR20170083121A (ko) 2017-07-17
AU2015348778B2 (en) 2020-12-24
ES2663836T3 (es) 2018-04-17
CN107072989A (zh) 2017-08-18
PL3180005T3 (pl) 2018-06-29
US20170319568A1 (en) 2017-11-09
IL252174B (en) 2021-02-28
NZ732704A (en) 2022-01-28
CA2967112C (en) 2023-05-16

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KG TJ TM