EA201790615A1 - Композиции и способы увеличения захвата железа у млекопитающих - Google Patents

Композиции и способы увеличения захвата железа у млекопитающих

Info

Publication number
EA201790615A1
EA201790615A1 EA201790615A EA201790615A EA201790615A1 EA 201790615 A1 EA201790615 A1 EA 201790615A1 EA 201790615 A EA201790615 A EA 201790615A EA 201790615 A EA201790615 A EA 201790615A EA 201790615 A1 EA201790615 A1 EA 201790615A1
Authority
EA
Eurasian Patent Office
Prior art keywords
iron
mammals
raising
compositions
increasing
Prior art date
Application number
EA201790615A
Other languages
English (en)
Inventor
Джон Гилмер
Габор Радикс
Майкл Велехан
Дзун Ван
Пат О'Флинн
Марк Ледвидж
Original Assignee
Солвотрин Терапьютикс Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Солвотрин Терапьютикс Лимитед filed Critical Солвотрин Терапьютикс Лимитед
Publication of EA201790615A1 publication Critical patent/EA201790615A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Приготовлены композиции, содержащие железо и денатурированный белок, которые способны повышать катионы железа и других двухвалентных металлов в сыворотке у больного. Например, приготовлены съедобные микрогранулы, содержащие железо, включенное в белковую матрицу, которая предоставляет гастропротективное действие и улучшает биодоступность железа по отношению к ранее известным носителям для доставки железа больному.
EA201790615A 2014-09-15 2015-09-15 Композиции и способы увеличения захвата железа у млекопитающих EA201790615A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1416293.7A GB201416293D0 (en) 2014-09-15 2014-09-15 Methods and preparations
US201562146897P 2015-04-13 2015-04-13
PCT/EP2015/071141 WO2016041995A1 (en) 2014-09-15 2015-09-15 Compositions and methods for increasing iron intake in a mammal

Publications (1)

Publication Number Publication Date
EA201790615A1 true EA201790615A1 (ru) 2017-08-31

Family

ID=51869639

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201790615A EA201790615A1 (ru) 2014-09-15 2015-09-15 Композиции и способы увеличения захвата железа у млекопитающих

Country Status (13)

Country Link
US (1) US11224614B2 (ru)
EP (1) EP3193839A1 (ru)
CN (1) CN107072953A (ru)
AU (1) AU2015316871A1 (ru)
BR (1) BR112017005200A2 (ru)
CA (1) CA2961430A1 (ru)
EA (1) EA201790615A1 (ru)
GB (1) GB201416293D0 (ru)
IL (1) IL251193A0 (ru)
MX (1) MX2017003433A (ru)
SG (1) SG11201702092UA (ru)
WO (1) WO2016041995A1 (ru)
ZA (1) ZA201702585B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7193145B2 (ja) * 2016-03-15 2022-12-20 ソルボトリン セラピューティクス リミテッド 哺乳動物において鉄摂取を増加させるための組成物及び方法
ES2925656T3 (es) * 2016-04-29 2022-10-19 Rousselot B V Excipiente basado en proteínas para principios farmacéuticos activos
BE1023653B1 (nl) * 2016-04-29 2017-06-07 Rousselot B.V. Eiwit gebaseerd excipient voor actieve farmaceutische stoffen
KR20190099455A (ko) * 2016-12-23 2019-08-27 유니버시티 오브 코펜하겐 단백질 및 물질의 공동-무정형 형태
IT201700039524A1 (it) * 2017-04-10 2018-10-10 Labomar S R L Composizioni orali per il trattamento di disturbi da carenza di ferro
CN108157727A (zh) * 2017-11-30 2018-06-15 慈中华 用于保持平和体质的固体饮料及其加工方法
US11350657B2 (en) 2018-08-06 2022-06-07 Pharmavite, Llc Protein gummy composition

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US505986A (en) * 1893-10-03 Pio marfori
US4167564A (en) 1974-09-23 1979-09-11 Albion Laboratories, Inc. Biological assimilation of metals
US4067994A (en) 1976-03-26 1978-01-10 Zinpro Corporation Iron methionine complex salts
US4216144A (en) 1977-10-20 1980-08-05 Ashmead H H Soluble iron proteinates
IT1150213B (it) 1982-03-02 1986-12-10 Italfarmaco Spa Derivati di ferro biodisponibile esenti da gastrolesivita',procentimento di preparazione e relative composizioni farmaceutiche
IT1186787B (it) 1985-11-06 1987-12-16 Mediolanum Farmaceutici Srl Ferro-derivati della globina e dell'acetilglobina dotati di elevata biodisponibilita',processo di preparazione e composizioni farmaceutiche
US5418010A (en) * 1990-10-05 1995-05-23 Griffith Laboratories Worldwide, Inc. Microencapsulation process
JP3404294B2 (ja) 1998-08-11 2003-05-06 雪印乳業株式会社 鉄−ホエー蛋白質加水分解物複合体
US6521247B1 (en) 1999-08-13 2003-02-18 Warner Chilcott Laboratories Ireland Limited Dual iron containing nutritional supplement
CA2543264C (en) * 2003-10-30 2012-06-26 Arla Foods Amba Stabilisers useful in low fat spread production
CN1557481A (zh) 2004-02-04 2004-12-29 高春平 防治缺铁性贫血的天然营养剂
US20060134227A1 (en) 2004-12-22 2006-06-22 Bortz Jonathan D Compositions including iron
US7585527B2 (en) 2005-09-19 2009-09-08 Bala Venkataraman Composition and method for treating iron deficiency anemia
EP2056797A2 (en) 2006-08-25 2009-05-13 Boehringer Ingelheim International GmbH Controlled release system and method for manufacturing the same
CN101143011B (zh) 2007-10-09 2011-06-22 浙江大学 提高食物中铁素生物有效性的方法
US20090124572A1 (en) 2007-11-09 2009-05-14 Deanna Jean Nelson Iron-containing nutritional supplement
CN101928742B (zh) * 2009-06-23 2013-02-27 光明乳业股份有限公司 一种具有抗氧化性活性的乳清蛋白活性肽及其制备方法
WO2012097155A1 (en) 2011-01-14 2012-07-19 Chiasma Inc. Improved pharmaceutical compositions for delivery of ferric iron compounds, and methods of use thereof
RU2014105619A (ru) 2011-07-15 2015-08-27 Нестек С.А. Пищевой инкапсулянт и способ его производства
MX2014003327A (es) * 2011-09-22 2014-07-09 Amip Promotor de absorcion gi superior amortiguado.
WO2014148886A1 (en) 2013-03-22 2014-09-25 N.V. Nutricia Fermented nutrition high in lactose with increased iron bioavailability
EP2995205A1 (en) 2014-09-15 2016-03-16 Anabio Technologies Limited Compositions and methods for the maintenance of adequate iron intake in a mammal

Also Published As

Publication number Publication date
SG11201702092UA (en) 2017-04-27
ZA201702585B (en) 2021-06-30
US11224614B2 (en) 2022-01-18
BR112017005200A2 (pt) 2018-03-06
GB201416293D0 (en) 2014-10-29
AU2015316871A1 (en) 2017-05-04
CN107072953A (zh) 2017-08-18
CA2961430A1 (en) 2016-03-24
WO2016041995A1 (en) 2016-03-24
MX2017003433A (es) 2017-11-13
US20160073668A1 (en) 2016-03-17
IL251193A0 (en) 2017-05-29
EP3193839A1 (en) 2017-07-26

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