EA201692375A1 - Антитело-опосредованные вакцины и способы их применения для получения быстрых зрелых иммунных ответов - Google Patents

Антитело-опосредованные вакцины и способы их применения для получения быстрых зрелых иммунных ответов

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EA201692375A1
EA201692375A1 EA201692375A EA201692375A EA201692375A1 EA 201692375 A1 EA201692375 A1 EA 201692375A1 EA 201692375 A EA201692375 A EA 201692375A EA 201692375 A EA201692375 A EA 201692375A EA 201692375 A1 EA201692375 A1 EA 201692375A1
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Prior art keywords
vaccines
methods
immune responses
antibody
application
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EA201692375A
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English (en)
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Люк Бергман
Чан-Син Чэн
Вэнь-Ко Чоу
Кристин Вуонг
Суриакант Вагхела
Вайтхака Мванги
Билли Харджис
Даад Аби-Гханем
Лиза Билк
Original Assignee
Дзе Борд Оф Трастиз Оф Дзе Юниверсити Оф Арканзас
Дзе Тексас Эй Энд Эм Юниверсити Систем
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Publication of EA201692375A1 publication Critical patent/EA201692375A1/ru

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Abstract

Настоящее изобретение относится к композициям адъюванта, вакцинам, конструкциям для получения композиций адъювантов и вакцин и способам применения композиций адъюванта и вакцин для усиления иммунных ответов у индивидуумов. В частности, вызывают быстрый гуморальный ответ на вакцину, включая IgG (в кровотоке) и sIgA (слизистый секреторный IgA). Адъюванты и вакцины можно применять для подкожного введения или введения через слизистые оболочки, делающего возможной дешевую, эффективную вакцинацию индивидуумов. Кроме того, настоящее изобретение относится к способу эпитопного картирования для быстрой идентификации антигенных эпитопов.
EA201692375A 2014-06-05 2015-06-04 Антитело-опосредованные вакцины и способы их применения для получения быстрых зрелых иммунных ответов EA201692375A1 (ru)

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US201462008178P 2014-06-05 2014-06-05
PCT/US2015/034229 WO2015187969A2 (en) 2014-06-05 2015-06-04 Antibody guided vaccines and methods of use for generation of rapid mature immune responses

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US (1) US20170196971A1 (ru)
EP (1) EP3151858A4 (ru)
JP (1) JP2017523136A (ru)
KR (1) KR20170007853A (ru)
CN (1) CN106535932A (ru)
AR (1) AR100740A1 (ru)
AU (1) AU2015269415A1 (ru)
BR (1) BR112016028418A2 (ru)
CA (1) CA2951041A1 (ru)
CL (1) CL2016003107A1 (ru)
EA (1) EA201692375A1 (ru)
MX (1) MX2016016080A (ru)
PH (1) PH12016502389A1 (ru)
SG (1) SG11201609965XA (ru)
TW (1) TW201613638A (ru)
WO (1) WO2015187969A2 (ru)

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AR108688A1 (es) 2016-05-03 2018-09-19 Univ Arkansas Vector de vacuna de levadura que incluye polipéptidos inmunoestimuladores y antigénicos, métodos para su uso
US20180362660A1 (en) * 2016-05-09 2018-12-20 Schickwann Tsai Anti-penumbra monoclonal antibodies for detection and therapy of normal and abnormal B lymphocytes
EP3470424A4 (en) * 2016-06-08 2020-03-04 Shanghai Jiaotong University School of Medicine SEQUENCE OF HEAVY CHAIN CONSTANT ANTIBODY REGION TO INCREASE AGONIST-ANTIBODY ACTIVITY
CN115956089A (zh) 2020-05-04 2023-04-11 加利福尼亚大学董事会 抑制性抗enpp1抗体
CN117164714B (zh) * 2023-10-08 2024-04-23 北京奇迈永华生物科技有限公司 一种靶向bcma的抗体及其应用

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AU6934600A (en) * 1999-08-27 2001-03-26 Board Of Regents, The University Of Texas System Cd40 ligand and cd40 agonist compositions and methods of use
WO2010053987A2 (en) * 2008-11-04 2010-05-14 Duke University Monoclonal antibody production in b cells and uses therof
CN106432493B (zh) * 2009-03-10 2020-01-31 贝勒研究院 抗-cd40抗体及其用途
KR101881611B1 (ko) * 2010-06-09 2018-07-25 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 캄필로박터 감염을 감소시키기 위한 백신 및 방법
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AR100740A1 (es) 2016-10-26
EP3151858A4 (en) 2018-01-17
WO2015187969A2 (en) 2015-12-10
CA2951041A1 (en) 2015-12-10
WO2015187969A3 (en) 2016-01-21
TW201613638A (en) 2016-04-16
JP2017523136A (ja) 2017-08-17
SG11201609965XA (en) 2016-12-29
AU2015269415A1 (en) 2017-01-05
BR112016028418A2 (pt) 2018-02-20
MX2016016080A (es) 2017-05-09
KR20170007853A (ko) 2017-01-20
PH12016502389A1 (en) 2017-02-20
CL2016003107A1 (es) 2017-05-19
AU2015269415A2 (en) 2017-01-19

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