EA201590673A1 - Слоистые двойные гидроксиды - Google Patents

Слоистые двойные гидроксиды

Info

Publication number
EA201590673A1
EA201590673A1 EA201590673A EA201590673A EA201590673A1 EA 201590673 A1 EA201590673 A1 EA 201590673A1 EA 201590673 A EA201590673 A EA 201590673A EA 201590673 A EA201590673 A EA 201590673A EA 201590673 A1 EA201590673 A1 EA 201590673A1
Authority
EA
Eurasian Patent Office
Prior art keywords
ldh
active anionic
materials
layered double
double hydroxides
Prior art date
Application number
EA201590673A
Other languages
English (en)
Other versions
EA034124B1 (ru
Inventor
Клэр Томпсон
Марчело Леонардо Браво Кордеро
Дермот Майкл О'Харе
Original Assignee
Оксфорд Фармасайенс Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Оксфорд Фармасайенс Лимитед filed Critical Оксфорд Фармасайенс Лимитед
Publication of EA201590673A1 publication Critical patent/EA201590673A1/ru
Publication of EA034124B1 publication Critical patent/EA034124B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/52—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение предлагает материалы на основе слоистых двойных гидроксидов (LDH) и, в частности, новые способы изготовления улучшенных материалов LDH, которые содержат интеркалированные активные анионные соединения (улучшенные активные анионные материалы LDH). Улучшенные активные анионные материалы LDH отличаются своей высокой степенью устойчивости, которую демонстрируют их высокие значения коэффициента устойчивости частиц, и своей способностью удерживать практически полностью интеркалированное активное анионное соединение при отсутствии условий ионного обмена и/или при рН>4.
EA201590673A 2012-10-05 2013-10-01 Слоистые двойные гидроксиды EA034124B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1217911.5A GB201217911D0 (en) 2012-10-05 2012-10-05 Layered double hydroxides
PCT/GB2013/052554 WO2014053822A1 (en) 2012-10-05 2013-10-01 Layered double hydroxides

Publications (2)

Publication Number Publication Date
EA201590673A1 true EA201590673A1 (ru) 2015-08-31
EA034124B1 EA034124B1 (ru) 2019-12-30

Family

ID=47294361

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201590673A EA034124B1 (ru) 2012-10-05 2013-10-01 Слоистые двойные гидроксиды

Country Status (16)

Country Link
US (1) US9642919B2 (ru)
EP (2) EP2929876B1 (ru)
JP (1) JP6363082B2 (ru)
KR (1) KR20150063559A (ru)
CN (1) CN104853748A (ru)
AU (2) AU2013326298B2 (ru)
BR (1) BR112015007529A2 (ru)
CA (1) CA2887059A1 (ru)
EA (1) EA034124B1 (ru)
GB (1) GB201217911D0 (ru)
IL (1) IL237947B (ru)
IN (1) IN2015DN02576A (ru)
MX (1) MX2015004188A (ru)
PH (1) PH12015500744A1 (ru)
WO (1) WO2014053822A1 (ru)
ZA (2) ZA201502510B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201520762D0 (en) * 2015-11-24 2016-01-06 Isis Innovation Novel pharmaceutical compositions
JP6557597B2 (ja) * 2015-12-25 2019-08-07 共栄社化学株式会社 層状複水酸化物
WO2018050799A1 (en) * 2016-09-15 2018-03-22 Paris Sciences Et Lettres - Quartier Latin A method for exchanging interlayer anions of a layered double hydroxide
CN109432450B (zh) * 2018-11-23 2021-07-13 北京化工大学 一种超分子纳米化学动力药物及其在肿瘤治疗方面的应用
US20220211748A1 (en) * 2019-04-19 2022-07-07 National Institute For Materials Science Nitrogenous gas sustained releasing agent and nitrogenous gas sustained releaser composed of the same as well as nitrogenous gas sustained releasing method, respiratory equipment, package, and sustained releasing apparatus using the sustained releaser

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS606619A (ja) * 1983-06-27 1985-01-14 Kyowa Chem Ind Co Ltd 鉄分欠乏症処置剤及びその製法
US5079203A (en) 1990-05-25 1992-01-07 Board Of Trustees Operating Michigan State University Polyoxometalate intercalated layered double hydroxides
JP3681480B2 (ja) * 1996-09-27 2005-08-10 エーザイ株式会社 薬物の不快な味を隠蔽する組成物
GB0030460D0 (en) * 2000-12-14 2001-01-24 Isis Innovation Drug delivery system
JP4018983B2 (ja) 2000-12-19 2007-12-05 バブコック アンド ウイルコックス ボルンド エイピーエス 有害な廃棄物からオキシアニオン形成元素、特にクロムの浸出を減少させる方法
JP2004091421A (ja) * 2002-09-03 2004-03-25 Tayca Corp アスコルビン酸を取り込んだ層状複水酸化物およびそれを含む化粧料組成物
US20040138511A1 (en) 2003-01-10 2004-07-15 James Butler Aromatic alkylation process with direct recycle
AU2003902178A0 (en) 2003-05-07 2003-05-22 Commonwealth Scientific And Industrial Research Organisation Stabilization of waste material
CN1297276C (zh) 2004-06-14 2007-01-31 北京化工大学 5－氨基水杨酸插层药物缓释剂及其制备方法
US20090108233A1 (en) * 2004-12-24 2009-04-30 The Univeristy Of Queensland Preparation of suspensions
US20060140994A1 (en) 2004-12-27 2006-06-29 Bagwell Alison S Application of an antimicrobial agent on an elastomeric article
MY157620A (en) * 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
CN100462071C (zh) * 2006-09-22 2009-02-18 北京化工大学 一种磁性超分子插层结构缓释型布洛芬及其制备方法
CN101493404B (zh) 2008-01-21 2011-08-10 安徽帝元生物科技有限公司 一种化肥养分控失剂控失率的检测方法
CN101440281B (zh) * 2008-11-25 2011-11-23 北京化工大学 苯并咔唑插层水滑石复合发光材料及其制备方法
ZA201000350B (en) 2009-02-05 2010-12-29 Univ Pretoria A degradable polymeric material
CN101507819B (zh) * 2009-03-27 2011-01-05 北京化工大学 一种大粒径药物插层水滑石及其制备方法
CN101597474B (zh) 2009-07-03 2012-10-17 北京化工大学 增甘磷插层结构选择性红外吸收材料及其制备方法与应用
US20110040006A1 (en) 2009-08-17 2011-02-17 Basf Se Compositions with Improved Dirt Pickup Resistance Comprising Layered Double Hydroxide Particles
CN102218043B (zh) 2011-06-14 2013-03-27 宁夏医科大学 Ldh超分子组装型阿司匹林缓释片及其制备方法

Also Published As

Publication number Publication date
IN2015DN02576A (ru) 2015-09-11
PH12015500744B1 (en) 2015-05-25
AU2017219016B2 (en) 2018-07-26
BR112015007529A2 (pt) 2017-07-04
KR20150063559A (ko) 2015-06-09
AU2013326298A1 (en) 2015-04-23
US20150258212A1 (en) 2015-09-17
WO2014053822A4 (en) 2014-05-30
CA2887059A1 (en) 2014-04-10
EP2929876A1 (en) 2015-10-14
JP2016500667A (ja) 2016-01-14
CN104853748A (zh) 2015-08-19
EP2929876B1 (en) 2019-12-25
IL237947B (en) 2018-04-30
US9642919B2 (en) 2017-05-09
PH12015500744A1 (en) 2015-05-25
EP2903598A1 (en) 2015-08-12
WO2014053822A1 (en) 2014-04-10
AU2013326298B2 (en) 2017-10-05
EP2903598B1 (en) 2019-05-01
MX2015004188A (es) 2015-07-17
GB201217911D0 (en) 2012-11-21
ZA201502510B (en) 2017-09-27
ZA201702869B (en) 2018-08-29
AU2017219016A1 (en) 2017-09-07
EA034124B1 (ru) 2019-12-30
JP6363082B2 (ja) 2018-07-25

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG TJ TM RU

NF4A Restoration of lapsed right to a eurasian patent

Designated state(s): RU