EA201491695A1 - Лечение рака ингибиторами tor-киназы - Google Patents

Лечение рака ингибиторами tor-киназы

Info

Publication number
EA201491695A1
EA201491695A1 EA201491695A EA201491695A EA201491695A1 EA 201491695 A1 EA201491695 A1 EA 201491695A1 EA 201491695 A EA201491695 A EA 201491695A EA 201491695 A EA201491695 A EA 201491695A EA 201491695 A1 EA201491695 A1 EA 201491695A1
Authority
EA
Eurasian Patent Office
Prior art keywords
treatment
breast cancer
cancer
tor
kinase inhibitors
Prior art date
Application number
EA201491695A
Other languages
English (en)
Other versions
EA039396B1 (ru
Inventor
Шуйчань Сюй
Кристен Мей Хедж
Хитер Рэймон
Рама К. Нарла
Original Assignee
СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи filed Critical СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи
Priority claimed from PCT/US2013/031185 external-priority patent/WO2013138553A1/en
Publication of EA201491695A1 publication Critical patent/EA201491695A1/ru
Publication of EA039396B1 publication Critical patent/EA039396B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Представлены способы лечения и предотвращения рака молочной железы с тройным негативным фенотипом или гормон-рецепторного положительного рака молочной железы, включающие введение эффективного количества ингибитора TOR-киназы пациенту, имеющему рак молочной железы с тройным негативным фенотипом или гормон-рецепторный положительный рак молочной железы.
EA201491695A 2012-10-18 2013-03-14 Лечение рака молочной железы с тройным негативным фенотипом ингибиторами tor-киназы EA039396B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261715331P 2012-10-18 2012-10-18
PCT/US2013/031185 WO2013138553A1 (en) 2012-03-15 2013-03-14 Treatment of cancer with tor kinase inhibitors

Publications (2)

Publication Number Publication Date
EA201491695A1 true EA201491695A1 (ru) 2015-02-27
EA039396B1 EA039396B1 (ru) 2022-01-24

Family

ID=80685582

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201491695A EA039396B1 (ru) 2012-10-18 2013-03-14 Лечение рака молочной железы с тройным негативным фенотипом ингибиторами tor-киназы

Country Status (1)

Country Link
EA (1) EA039396B1 (ru)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008051493A2 (en) * 2006-10-19 2008-05-02 Signal Pharmaceuticals, Llc Heteroaryl compounds, compositions thereof, and their use as protein kinase inhibitors
MX2009004019A (es) * 2006-10-19 2009-06-19 Signal Pharm Llc Compuestos heteroarilo, composiciones de los mismos, y uso de los mismos como inhibidores de proteina cinasa.
JP2011516580A (ja) * 2008-04-11 2011-05-26 バイオノボ・インコーポレーテッド トウサイカチｇｌｅｄｉｔｓｉａｓｉｎｅｎｓｉｓｌａｍの抽出物を用いる抗癌方法
US8110578B2 (en) * 2008-10-27 2012-02-07 Signal Pharmaceuticals, Llc Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway

Also Published As

Publication number Publication date
EA039396B1 (ru) 2022-01-24

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