EA201391643A1 - Составы с замедленным высвобождением парацетамола - Google Patents

Составы с замедленным высвобождением парацетамола

Info

Publication number
EA201391643A1
EA201391643A1 EA201391643A EA201391643A EA201391643A1 EA 201391643 A1 EA201391643 A1 EA 201391643A1 EA 201391643 A EA201391643 A EA 201391643A EA 201391643 A EA201391643 A EA 201391643A EA 201391643 A1 EA201391643 A1 EA 201391643A1
Authority
EA
Eurasian Patent Office
Prior art keywords
paracetamol
delayed
delivery
compositions
phase
Prior art date
Application number
EA201391643A
Other languages
English (en)
Inventor
Карла Валенти Бюан
Дунчжоу Лю
Канджи Мегхпара
Original Assignee
ГЛЭКСОСМИТКЛАЙН ЭлЭлСи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ГЛЭКСОСМИТКЛАЙН ЭлЭлСи filed Critical ГЛЭКСОСМИТКЛАЙН ЭлЭлСи
Publication of EA201391643A1 publication Critical patent/EA201391643A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Abstract

Изобретение относится к фармацевтической композиции с замедленным высвобождением парацетамола, имеющей фазу немедленного высвобождения и фазу замедленного высвобождения парацетамола и обладающей уникальными и благоприятными фармакокинетическими свойствами, и к композиции, содержащей только фазу парацетамола с замедленным высвобождением и обладающей уникальными и благоприятными фармакокинетическими свойствами.
EA201391643A 2011-05-06 2012-05-04 Составы с замедленным высвобождением парацетамола EA201391643A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161483320P 2011-05-06 2011-05-06
PCT/US2012/036528 WO2012154563A1 (en) 2011-05-06 2012-05-04 Sustained release paracetamol formulations

Publications (1)

Publication Number Publication Date
EA201391643A1 true EA201391643A1 (ru) 2014-07-30

Family

ID=47139543

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201391643A EA201391643A1 (ru) 2011-05-06 2012-05-04 Составы с замедленным высвобождением парацетамола

Country Status (19)

Country Link
US (1) US20140065213A1 (ru)
EP (1) EP2704697B1 (ru)
CN (1) CN103648486A (ru)
AP (1) AP3878A (ru)
AU (1) AU2012253834B2 (ru)
BR (1) BR112013028668A2 (ru)
CA (1) CA2835330A1 (ru)
CL (1) CL2013003176A1 (ru)
CO (1) CO6801767A2 (ru)
CR (1) CR20130572A (ru)
DO (1) DOP2013000258A (ru)
EA (1) EA201391643A1 (ru)
GT (1) GT201300270A (ru)
MX (1) MX2013012918A (ru)
NI (1) NI201300116A (ru)
SG (1) SG194605A1 (ru)
TW (1) TW201306881A (ru)
WO (1) WO2012154563A1 (ru)
ZA (1) ZA201308316B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
TW201507726A (zh) * 2013-05-10 2015-03-01 Glaxosmithkline Llc 菸鹼菱形錠配製物
BE1021194B1 (nl) * 2014-07-07 2015-07-14 Nordic Specialty Pharma Bvba Paracetamol tabletten
EA033298B1 (ru) 2015-03-03 2019-09-30 Саниона А/С Комбинированная лекарственная форма тезофензина и метопролола
BE1023116B1 (nl) * 2015-07-24 2016-11-23 Nordic Specialty Pharma Bvba Paracetamol omvattend preparaat met vertraagde en aanhoudende afgifte

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820522A (en) * 1987-07-27 1989-04-11 Mcneilab, Inc. Oral sustained release acetaminophen formulation and process
GB8724763D0 (en) * 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations
US5009895A (en) * 1990-02-02 1991-04-23 Merck & Co., Inc. Sustained release with high and low viscosity HPMC
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
AUPN940796A0 (en) * 1996-04-23 1996-05-16 F.H. Faulding & Co. Limited Taste masked pharmaceutical compositions
US20030064108A1 (en) * 1996-04-23 2003-04-03 Stefan Lukas Taste masked pharmaceutical compositions
US6599529B1 (en) * 1997-09-11 2003-07-29 Nycomed Danmark A/S Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (NSAIDs)
IL141762A0 (en) * 1998-10-01 2002-03-10 Novartis Ag New oral formulations
GB0009522D0 (en) * 2000-04-19 2000-06-07 Smithkline Beecham Plc Composition
GB0114069D0 (en) * 2001-06-08 2001-08-01 Smithkline Beecham Plc Composition
EP1519717B1 (en) * 2002-07-05 2010-09-29 Temrel Limited Controlled release composition
US20080031901A1 (en) * 2004-09-24 2008-02-07 Abbott Laboratories Sustained release monoeximic formulations of opioid and nonopioid analgesics
JP5563731B2 (ja) * 2003-09-26 2014-07-30 アルザ・コーポレーシヨン オピオイドおよび非オピオイド鎮痛薬の制御放出製剤
GB2431346C (en) * 2004-07-07 2010-02-17 Aft Pharmaceuticals Ltd A combination composition comprising paracetamol and ibuprofen
EP2271330A1 (en) * 2008-02-01 2011-01-12 Abbott Laboratories Extended release hydrocodone acetaminophen and related methods and uses thereof
JP5607550B2 (ja) * 2008-03-11 2014-10-15 ディポメド，インコーポレイティド 非オピオイド鎮痛剤及びオピオイド鎮痛剤の組合せを含む胃保持性持続放出剤形
KR20110036858A (ko) * 2008-10-27 2011-04-11 알자 코퍼레이션 지속 방출형 경구용 아세트아미노펜/트라마돌 제형
US8021420B2 (en) * 2009-03-12 2011-09-20 Medtronic Vascular, Inc. Prosthetic valve delivery system
AU2010286354A1 (en) * 2009-08-31 2012-04-19 Depomed, Inc. Gastric retentive pharmaceutical compositions for immediate and extended release of acetaminophen

Also Published As

Publication number Publication date
NI201300116A (es) 2014-11-13
ZA201308316B (en) 2014-07-30
US20140065213A1 (en) 2014-03-06
TW201306881A (zh) 2013-02-16
EP2704697A1 (en) 2014-03-12
CN103648486A (zh) 2014-03-19
NZ617198A (en) 2016-01-29
BR112013028668A2 (pt) 2017-01-24
CO6801767A2 (es) 2013-11-29
EP2704697A4 (en) 2015-01-07
AP2013007224A0 (en) 2013-11-30
AU2012253834A1 (en) 2013-12-05
AP3878A (en) 2016-10-31
DOP2013000258A (es) 2014-07-15
AU2012253834B2 (en) 2016-06-16
WO2012154563A1 (en) 2012-11-15
SG194605A1 (en) 2013-12-30
CL2013003176A1 (es) 2014-07-04
CA2835330A1 (en) 2012-11-15
MX2013012918A (es) 2013-11-21
CR20130572A (es) 2014-03-20
EP2704697B1 (en) 2018-09-12
GT201300270A (es) 2014-12-16

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