EA201270767A1 - Терапия на основе лигандов хемосенсорных рецепторов - Google Patents

Терапия на основе лигандов хемосенсорных рецепторов

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Publication number
EA201270767A1
EA201270767A1 EA201270767A EA201270767A EA201270767A1 EA 201270767 A1 EA201270767 A1 EA 201270767A1 EA 201270767 A EA201270767 A EA 201270767A EA 201270767 A EA201270767 A EA 201270767A EA 201270767 A1 EA201270767 A1 EA 201270767A1
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EA
Eurasian Patent Office
Prior art keywords
ligands
receptors
chemosensor
therapy
basis
Prior art date
Application number
EA201270767A
Other languages
English (en)
Inventor
Элейн Бэрон
Мартин Р. Браун
Кристофер Р.Г. Джонс
Original Assignee
Элселикс Терапьютикс, Инк.
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Application filed by Элселикс Терапьютикс, Инк. filed Critical Элселикс Терапьютикс, Инк.
Publication of EA201270767A1 publication Critical patent/EA201270767A1/ru

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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/13Amines
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Abstract

Изобретение включает способы лечения диабета, ожирения и других метаболических заболеваний, нарушений или патологических состояний с участием лигандов хемосенсорных рецепторов. Также данная заявка включает композиции лигандов хемосенсорных рецепторов и их приготовление для применения в способах по настоящему изобретению.
EA201270767A 2010-04-20 2010-10-19 Терапия на основе лигандов хемосенсорных рецепторов EA201270767A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/763,926 US9901551B2 (en) 2009-04-20 2010-04-20 Chemosensory receptor ligand-based therapies
PCT/US2010/053257 WO2011133180A1 (en) 2010-04-20 2010-10-19 Chemosensory receptor ligand-based therapies

Publications (1)

Publication Number Publication Date
EA201270767A1 true EA201270767A1 (ru) 2013-06-28

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Application Number Title Priority Date Filing Date
EA201270767A EA201270767A1 (ru) 2010-04-20 2010-10-19 Терапия на основе лигандов хемосенсорных рецепторов

Country Status (14)

Country Link
US (1) US9901551B2 (ru)
EP (1) EP2560660A4 (ru)
JP (1) JP5907952B2 (ru)
KR (1) KR101881608B1 (ru)
CN (2) CN106039313A (ru)
AR (1) AR078678A1 (ru)
BR (1) BR112012026838A2 (ru)
CA (1) CA2800470A1 (ru)
EA (1) EA201270767A1 (ru)
IL (1) IL222586A0 (ru)
MX (1) MX2012012157A (ru)
SG (3) SG184935A1 (ru)
WO (1) WO2011133180A1 (ru)
ZA (1) ZA201208277B (ru)

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JP5907952B2 (ja) 2016-04-26
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US20100267643A1 (en) 2010-10-21
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SG184935A1 (en) 2012-11-29
US9901551B2 (en) 2018-02-27
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CN102946885A (zh) 2013-02-27
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CA2800470A1 (en) 2011-10-27
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