EA201201675A1 - Производные 6,7-дигидро-5h-бензо[7]аннулена, способы их получения, фармацевтические препараты, содержащие их, и их применение для получения лекарственных средств - Google Patents

Производные 6,7-дигидро-5h-бензо[7]аннулена, способы их получения, фармацевтические препараты, содержащие их, и их применение для получения лекарственных средств

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EA201201675A1
EA201201675A1 EA201201675A EA201201675A EA201201675A1 EA 201201675 A1 EA201201675 A1 EA 201201675A1 EA 201201675 A EA201201675 A EA 201201675A EA 201201675 A EA201201675 A EA 201201675A EA 201201675 A1 EA201201675 A1 EA 201201675A1
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methods
unnuled
benzo
dihydro
tools
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EA201201675A
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EA022547B1 (ru
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Тим Винтермантель
Карстен Мёллер
Ульрих Боте
Райнхард Нуббемейер
Лудвиг Цорн
Дирк Коземунд
Антониус Тер Лак
Рольф Больманн
Ларс Вортманн
Доналд Бирер
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Байер Интеллектчуал Проперти Гмбх
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Application filed by Байер Интеллектчуал Проперти Гмбх filed Critical Байер Интеллектчуал Проперти Гмбх
Publication of EA201201675A1 publication Critical patent/EA201201675A1/ru
Publication of EA022547B1 publication Critical patent/EA022547B1/ru

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Abstract

Изобретение относится к селективным модуляторам эстрогеновых рецепторов (SERM) и способам их получения, их применению для лечения и/или профилактики заболеваний и их применению для получения лекарственных средств для лечения и/или профилактики заболеваний, в частности нарушений свертываемости, остеопороза, эндометриоза, миом, гормонозависимых опухолей, для гормонозаместительной терапии и для контрацепции.
EA201201675A 2010-06-25 2011-06-21 Производные 6,7-дигидро-5h-бензо[7]аннулена, способы их получения, фармацевтические препараты, содержащие их, и их применение для получения лекарственных средств EA022547B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102010030538A DE102010030538A1 (de) 2010-06-25 2010-06-25 6,7-Dihydro-5H-benzo[7]annulen-Derivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate die diese enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln
PCT/EP2011/060335 WO2011161101A1 (de) 2010-06-25 2011-06-21 6,7-dihydro-5h-benzo[7]annulen-derivate, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln

Publications (2)

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EA201201675A1 true EA201201675A1 (ru) 2013-06-28
EA022547B1 EA022547B1 (ru) 2016-01-29

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EA201201675A EA022547B1 (ru) 2010-06-25 2011-06-21 Производные 6,7-дигидро-5h-бензо[7]аннулена, способы их получения, фармацевтические препараты, содержащие их, и их применение для получения лекарственных средств

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US (1) US20130252890A1 (ru)
EP (1) EP2585435A1 (ru)
JP (1) JP5530031B2 (ru)
KR (1) KR20130089238A (ru)
CN (1) CN103080080B (ru)
AR (1) AR081671A1 (ru)
AU (1) AU2011269067B2 (ru)
BR (1) BR112012032758A2 (ru)
CA (1) CA2803690A1 (ru)
CL (1) CL2012003648A1 (ru)
CO (1) CO6660506A2 (ru)
CR (1) CR20120657A (ru)
CU (1) CU24106B1 (ru)
DE (1) DE102010030538A1 (ru)
DO (1) DOP2012000325A (ru)
EA (1) EA022547B1 (ru)
EC (1) ECSP12012355A (ru)
GT (1) GT201200347A (ru)
IL (1) IL223770A (ru)
MA (1) MA34333B1 (ru)
MX (1) MX2013000181A (ru)
NZ (1) NZ605061A (ru)
PE (1) PE20131196A1 (ru)
SG (1) SG186437A1 (ru)
TN (1) TN2012000618A1 (ru)
TW (1) TW201204347A (ru)
UA (1) UA108759C2 (ru)
UY (1) UY33470A (ru)
WO (1) WO2011161101A1 (ru)

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MX2012014431A (es) 2010-06-10 2013-02-26 Aragon Pharmaceuticals Inc Modulares del receptor de estrogenos y usos de los mismos.
DE102011087987A1 (de) * 2011-12-08 2013-06-13 Bayer Intellectual Property Gmbh 6,7-Dihydro-5H-benzo[7]annulen-Derivate, Verfahren zu ihrer Herstellung, pharmazeutische Präparate die diese enthalten, sowie deren Verwendung zur Herstellung von Arzneimitteln
WO2013090829A1 (en) 2011-12-14 2013-06-20 Aragon Pharmaceuticals, Inc. Estrogen receptor modulators and uses thereof
WO2015028409A1 (de) * 2013-08-27 2015-03-05 Bayer Pharma Aktiengesellschaft 6,7-dihydro-5h-benzo[7]annulen-derivate, verfahren zu ihrer herstellung, pharmazeutische präparate die diese enthalten, sowie deren verwendung zur herstellung von arzneimitteln
JP6425852B1 (ja) * 2016-02-15 2018-11-21 サノフイＳａｎｏｆｉ エストロゲン受容体調節剤としての６，７−ジヒドロ−５ｈ−ベンゾ［７］アヌレン誘導体
WO2018091153A1 (en) 2016-11-17 2018-05-24 Sanofi Novel substituted n-(3-fluoropropyl)-pyrrolidine compounds, processes for their preparation and therapeutic uses thereof
EP3434272A1 (en) 2017-07-25 2019-01-30 Sanofi Combination comprising palbociclib and 6-(2,4-dichlorophenyl)-5-[4-[(3s)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7h-benzo[7]annulene-2-carboxylic acid
CN107325028B (zh) * 2017-08-16 2019-01-18 连云港恒运药业有限公司 氟维司群侧链中间体合成方法
CN109020794A (zh) * 2018-08-27 2018-12-18 上海华堇生物技术有限责任公司 3-甲氧基肉桂醛的制备方法
CN109020795A (zh) * 2018-08-27 2018-12-18 上海华堇生物技术有限责任公司 4-甲氧基肉桂醛的制备方法
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CN111377996A (zh) * 2018-12-29 2020-07-07 江苏豪森药业集团有限公司 一种氟维司群有关物质的合成方法
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