EA200970239A1 - TITING REGIME OF BIFEPRUNOX FOR THE TREATMENT OF SCHIZOPHRENIA AND KITS FOR APPLICATION IN THIS AREA - Google Patents
TITING REGIME OF BIFEPRUNOX FOR THE TREATMENT OF SCHIZOPHRENIA AND KITS FOR APPLICATION IN THIS AREAInfo
- Publication number
- EA200970239A1 EA200970239A1 EA200970239A EA200970239A EA200970239A1 EA 200970239 A1 EA200970239 A1 EA 200970239A1 EA 200970239 A EA200970239 A EA 200970239A EA 200970239 A EA200970239 A EA 200970239A EA 200970239 A1 EA200970239 A1 EA 200970239A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- bifeprunox
- treatment
- titing
- schizophrenia
- regime
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Abstract
Настоящее изобретение направлено на применение соединения бифепрунокса для набора для титрования для режима титрования, чтобы облегчить начало лечения приблизительно одного из состояний или расстройств центральной нервной системы (ЦНС) при помощи введения множества дозировок состава, содержащего соединение 7-[4-([1,1'-бифенил]-3-ильметил)-1-пиперазинил]-2(3Н)-бензоксазолон (МНН бифепрунокс).The present invention is directed to the use of a bifeprunox compound for a titration kit for a titration regimen to facilitate the initiation of treatment of approximately one of a condition or disorder of the central nervous system (CNS) by administering multiple dosages of a composition containing compound 7- [4 - ([1,1 '-biphenyl] -3-ylmethyl) -1-piperazinyl] -2 (3H) benzoxazolone (INN bifeprunox).
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US84124406P | 2006-08-31 | 2006-08-31 | |
EP06119936 | 2006-08-31 | ||
US84149506P | 2006-09-01 | 2006-09-01 | |
EP06120016 | 2006-09-01 | ||
PCT/EP2007/058957 WO2008025780A1 (en) | 2006-08-31 | 2007-08-29 | Titration schedule for bifeprunox for treating schizophrenia and kits for use therein |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200970239A1 true EA200970239A1 (en) | 2009-08-28 |
Family
ID=38704953
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200970239A EA200970239A1 (en) | 2006-08-31 | 2007-08-29 | TITING REGIME OF BIFEPRUNOX FOR THE TREATMENT OF SCHIZOPHRENIA AND KITS FOR APPLICATION IN THIS AREA |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP2059245A1 (en) |
JP (2) | JP2010501626A (en) |
KR (1) | KR20090063228A (en) |
AU (2) | AU2007291234A1 (en) |
BR (1) | BRPI0715445A2 (en) |
CA (2) | CA2661120A1 (en) |
EA (1) | EA200970239A1 (en) |
IL (1) | IL196867A0 (en) |
NO (1) | NO20091243L (en) |
WO (2) | WO2008025780A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010060742A1 (en) * | 2008-11-03 | 2010-06-03 | Solvay Pharmaceuticals B.V. | Combination of bifeprunox and an antipsychotic drug with d2/5-ht2a receptor antagonistic activity for treating cns disorders |
WO2010070061A1 (en) * | 2008-12-19 | 2010-06-24 | Abbott Healthcare Products B.V. | Compositions, kits and methods of a titration schedule for bifeprunox compounds |
LT2445502T (en) | 2009-06-25 | 2017-09-25 | Alkermes Pharma Ireland Limited | Heterocyclic compounds for the treatment of neurological and psychological disorders |
WO2011023796A1 (en) | 2009-08-31 | 2011-03-03 | Abbott Healthcare Products B.V. | Bifeprunox for treating addiction |
EP3718536A1 (en) | 2012-09-19 | 2020-10-07 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions having improved storage stability |
MA39495A (en) | 2014-03-20 | 2015-09-24 | Alkermes Pharma Ireland Ltd | ARIIPIPRAZOLE FORMULATIONS WITH HIGHER INJECTION RATES |
EP3761983A1 (en) | 2018-03-05 | 2021-01-13 | Alkermes Pharma Ireland Limited | Aripiprazole dosing strategy |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT889889E (en) * | 1996-03-29 | 2007-01-31 | Duphar Int Res | Piperazine and piperidine compounds |
CA2310950C (en) * | 2000-04-03 | 2005-11-08 | Janssen Pharmaceutica N.V. | An efficacious dosage regiment of galantamine that reduces side effects |
AR034206A1 (en) | 2001-02-16 | 2004-02-04 | Solvay Pharm Bv | A PROCEDURE FOR THE PREPARATION OF MESILATES OF PIPERAZINE DERIVATIVES AND SUCH MESILATES |
AR045362A1 (en) * | 2003-08-18 | 2005-10-26 | Solvay Pharm Bv | STABLE CRYSTALLINE FORM OF BIFEPRUNOX MESILATE (MONOMETANSULFONATE 7- [4 - ([1,1- BIFENIL] -3- ILMETIL) -1- PIPERAZINIL] - 2- (3H) -BENZOXAZOLONA |
US7423040B2 (en) * | 2005-02-18 | 2008-09-09 | Irene Eijgendaal | Stable crystalline form of bifeprunox mesylate, dosage forms thereof and methods for using same |
PT1919883E (en) | 2005-08-22 | 2009-03-26 | Solvay Pharm Bv | N-oxides as prodrugs of piperazine&piperidine derivatives |
-
2007
- 2007-08-29 BR BRPI0715445-3A patent/BRPI0715445A2/en not_active IP Right Cessation
- 2007-08-29 KR KR1020097006567A patent/KR20090063228A/en not_active Application Discontinuation
- 2007-08-29 AU AU2007291234A patent/AU2007291234A1/en not_active Abandoned
- 2007-08-29 WO PCT/EP2007/058957 patent/WO2008025780A1/en active Application Filing
- 2007-08-29 CA CA002661120A patent/CA2661120A1/en not_active Abandoned
- 2007-08-29 WO PCT/EP2007/058958 patent/WO2008025781A1/en active Application Filing
- 2007-08-29 AU AU2007291235A patent/AU2007291235A1/en not_active Abandoned
- 2007-08-29 JP JP2009526089A patent/JP2010501626A/en not_active Withdrawn
- 2007-08-29 EP EP07802975A patent/EP2059245A1/en not_active Withdrawn
- 2007-08-29 CA CA002661800A patent/CA2661800A1/en not_active Abandoned
- 2007-08-29 EP EP07802974A patent/EP2059244A1/en not_active Withdrawn
- 2007-08-29 EA EA200970239A patent/EA200970239A1/en unknown
- 2007-08-29 JP JP2009526088A patent/JP2010501625A/en not_active Withdrawn
-
2009
- 2009-02-03 IL IL196867A patent/IL196867A0/en unknown
- 2009-03-25 NO NO20091243A patent/NO20091243L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2008025780A1 (en) | 2008-03-06 |
IL196867A0 (en) | 2009-11-18 |
CA2661120A1 (en) | 2008-03-06 |
JP2010501625A (en) | 2010-01-21 |
AU2007291235A1 (en) | 2008-03-06 |
EP2059245A1 (en) | 2009-05-20 |
AU2007291234A1 (en) | 2008-03-06 |
BRPI0715445A2 (en) | 2014-05-13 |
WO2008025781A1 (en) | 2008-03-06 |
JP2010501626A (en) | 2010-01-21 |
CA2661800A1 (en) | 2008-03-06 |
EP2059244A1 (en) | 2009-05-20 |
NO20091243L (en) | 2009-03-25 |
KR20090063228A (en) | 2009-06-17 |
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