EA200801463A1 - HYPOALLERGENIC OPTIONS OF THE MAIN ALLERGEN FROM BETULA VERRUCOSA POLAND - Google Patents

HYPOALLERGENIC OPTIONS OF THE MAIN ALLERGEN FROM BETULA VERRUCOSA POLAND

Info

Publication number
EA200801463A1
EA200801463A1 EA200801463A EA200801463A EA200801463A1 EA 200801463 A1 EA200801463 A1 EA 200801463A1 EA 200801463 A EA200801463 A EA 200801463A EA 200801463 A EA200801463 A EA 200801463A EA 200801463 A1 EA200801463 A1 EA 200801463A1
Authority
EA
Eurasian Patent Office
Prior art keywords
poland
hypoallergenic
options
betula verrucosa
main allergen
Prior art date
Application number
EA200801463A
Other languages
Russian (ru)
Other versions
EA015446B1 (en
Inventor
Джованни Мистрелло
Стефания Дзанотта
Даниэла Ронкароло
Паоло Фаладжани
Original Assignee
Лофарма С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лофарма С.П.А. filed Critical Лофарма С.П.А.
Publication of EA200801463A1 publication Critical patent/EA200801463A1/en
Publication of EA015446B1 publication Critical patent/EA015446B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides hypoallergenic variants of Bet v 1 major allergen from Betula verrucosa plant pollen and the use thereof for the preventive or therapeutic treatment of allergic diseases.
EA200801463A 2005-12-29 2006-12-19 Hypoallergenic variants of the major allergen from betula verrucosa pollen EA015446B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT002517A ITMI20052517A1 (en) 2005-12-29 2005-12-29 VARIANBTIO HYPOALLERGENICS OF ALLERGENE GREATER BET V 1 BERRY OF BETULA VERRUCOSA
PCT/EP2006/012237 WO2007073907A1 (en) 2005-12-29 2006-12-19 Hypoallergenic variants of the major allergen from betula verrucosa pollen

Publications (2)

Publication Number Publication Date
EA200801463A1 true EA200801463A1 (en) 2008-12-30
EA015446B1 EA015446B1 (en) 2011-08-30

Family

ID=37891495

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200801463A EA015446B1 (en) 2005-12-29 2006-12-19 Hypoallergenic variants of the major allergen from betula verrucosa pollen

Country Status (18)

Country Link
US (1) US8945574B2 (en)
EP (2) EP1973567B1 (en)
JP (1) JP2009521910A (en)
CN (1) CN101351224B (en)
AT (1) ATE457738T1 (en)
AU (1) AU2006331005B2 (en)
BR (1) BRPI0620749A2 (en)
CA (1) CA2634955C (en)
DE (1) DE602006012376D1 (en)
DK (2) DK2172215T3 (en)
EA (1) EA015446B1 (en)
ES (2) ES2341367T3 (en)
IT (1) ITMI20052517A1 (en)
MX (1) MX2008008578A (en)
NO (1) NO20082881L (en)
PT (1) PT1973567E (en)
UA (1) UA93894C2 (en)
WO (1) WO2007073907A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2624030C2 (en) * 2011-08-03 2017-06-30 Лофарма С.П.А. Hypoallergenic variants of mal d 1, main malus domectica allergen

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2028188A1 (en) 2007-08-21 2009-02-25 Biomay AG Hypoallergenic molecules
ITMI20071819A1 (en) * 2007-09-19 2009-03-20 Lofarma Spa HYPOALLERGENIC VARIATIONS OF ALLERGENES GREATER BET V 2 BERRY OF BETULA VERRUCOSA
FI20115375A0 (en) 2011-04-18 2011-04-18 Teknologian Tutkimuskeskus Vtt Oy New hypoallergens
FI20115374A0 (en) 2011-04-18 2011-04-18 Teknologian Tutkimuskeskus Vtt Oy New hypoallergens
IL298034B2 (en) 2017-06-01 2024-05-01 Regeneron Pharma Human antibodies to bet v 1 and methods of use thereof
EP4175986A1 (en) 2020-07-01 2023-05-10 Regeneron Pharmaceuticals, Inc. Methods of treating allergy using anti-bet v 1 antibodies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5411594A (en) * 1992-10-27 1994-05-24 Biomay Produktions- Und Handelsgesellschaft M.B.H. Molecule fragments (peptides) of the main allergens contained in the pollen of trees of the (fagales) order
RU2193413C2 (en) * 1996-03-01 2002-11-27 Новартис Аг Peptide immunogens for vaccination and treatment of allergy
CA2323687C (en) * 1998-03-16 2008-11-25 Alk-Abello A/S Mutant recombinant allergens
AU2002223505B2 (en) * 2000-11-16 2006-12-07 Alk-Abello A/S Mutant allergens
US20040043438A1 (en) * 2002-05-16 2004-03-04 Alk-Abello A/S Allergen mutants
WO2003096869A2 (en) * 2002-05-16 2003-11-27 Alk Abelló A/S Recombinant bet. v. 1. allergen mutants, methods and process thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2624030C2 (en) * 2011-08-03 2017-06-30 Лофарма С.П.А. Hypoallergenic variants of mal d 1, main malus domectica allergen

Also Published As

Publication number Publication date
EA015446B1 (en) 2011-08-30
EP2172215A2 (en) 2010-04-07
DK2172215T3 (en) 2014-01-20
US20090304752A1 (en) 2009-12-10
NO20082881L (en) 2008-09-25
DE602006012376D1 (en) 2010-04-01
WO2007073907A1 (en) 2007-07-05
PT1973567E (en) 2010-05-12
EP2172215A3 (en) 2010-05-26
UA93894C2 (en) 2011-03-25
ES2441217T3 (en) 2014-02-03
BRPI0620749A2 (en) 2011-11-22
ITMI20052517A1 (en) 2007-06-30
US8945574B2 (en) 2015-02-03
ATE457738T1 (en) 2010-03-15
AU2006331005B2 (en) 2012-02-02
ES2341367T3 (en) 2010-06-18
EP1973567A1 (en) 2008-10-01
EP1973567B1 (en) 2010-02-17
CN101351224B (en) 2013-04-03
CN101351224A (en) 2009-01-21
AU2006331005A1 (en) 2007-07-05
MX2008008578A (en) 2008-09-26
CA2634955A1 (en) 2007-07-05
JP2009521910A (en) 2009-06-11
DK1973567T3 (en) 2010-05-31
EP2172215B1 (en) 2013-10-16
CA2634955C (en) 2017-02-28

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM