EA200800766A1 - Ингибиторы pi3k для лечения эндометриоза - Google Patents
Ингибиторы pi3k для лечения эндометриозаInfo
- Publication number
- EA200800766A1 EA200800766A1 EA200800766A EA200800766A EA200800766A1 EA 200800766 A1 EA200800766 A1 EA 200800766A1 EA 200800766 A EA200800766 A EA 200800766A EA 200800766 A EA200800766 A EA 200800766A EA 200800766 A1 EA200800766 A1 EA 200800766A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- endometriosis
- treatment
- pi3k inhibitors
- present
- pi3k inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Настоящее изобретение относится к способу лечения и/или профилактики эндометриоза, включающему введение ингибитора PI3K. Ингибитор PI3K может также вводиться в сочетании с супрессором гормонов. Настоящее изобретение дополнительно относится к лечению связанного с эндометриозом бесплодия.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71464405P | 2005-09-07 | 2005-09-07 | |
EP05109448 | 2005-10-11 | ||
PCT/US2006/033679 WO2007030360A2 (en) | 2005-09-07 | 2006-08-28 | P13k inhibitors for the treatment of endometriosis |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200800766A1 true EA200800766A1 (ru) | 2008-06-30 |
Family
ID=35713975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200800766A EA200800766A1 (ru) | 2005-09-07 | 2006-08-28 | Ингибиторы pi3k для лечения эндометриоза |
Country Status (9)
Country | Link |
---|---|
US (1) | US20080306057A1 (ru) |
EP (1) | EP1931424A2 (ru) |
AU (1) | AU2006287765B2 (ru) |
BR (1) | BRPI0615654A2 (ru) |
CA (1) | CA2618489A1 (ru) |
EA (1) | EA200800766A1 (ru) |
MX (1) | MX2008003189A (ru) |
NZ (1) | NZ565748A (ru) |
WO (1) | WO2007030360A2 (ru) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101052640B (zh) * | 2004-09-03 | 2011-05-11 | 默克雪兰诺有限公司 | 吡啶亚甲基唑烷酮类及其作为磷酸肌醇抑制剂的用途 |
WO2009026346A1 (en) * | 2007-08-20 | 2009-02-26 | Targegen Inc. | Thiazolidine compounds, and methods of making and using same |
ES2587738T3 (es) | 2007-12-21 | 2016-10-26 | Ucb Biopharma Sprl | Derivados de quinoxalina y quinolina como inhibidores de quinasa |
CN102348798A (zh) | 2009-01-16 | 2012-02-08 | 麻省理工学院 | 孤独症谱系障碍的诊断和治疗 |
US20100316639A1 (en) | 2009-06-16 | 2010-12-16 | Genentech, Inc. | Biomarkers for igf-1r inhibitor therapy |
JP6057896B2 (ja) | 2010-08-20 | 2017-01-11 | ノバルティス アーゲー | 上皮細胞増殖因子受容体3(her3)に対する抗体 |
CN108341873B (zh) | 2011-12-05 | 2022-03-25 | 诺华股份有限公司 | 表皮生长因子受体3(her3)的抗体 |
JP2018512403A (ja) * | 2015-03-09 | 2018-05-17 | バイエル ファーマ アクチエンゲゼルシャフト | 置換2,3−ジヒドロイミダゾ[1,2−c]キナゾリン類の使用 |
CN111315378A (zh) | 2017-11-16 | 2020-06-19 | 诺华股份有限公司 | 包含lsz102和瑞博西尼的药物组合 |
US10695333B2 (en) | 2017-12-01 | 2020-06-30 | Novartis Ag | Pharmaceutical combination comprising LSZ102 and alpelisib |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7799766B2 (en) * | 1998-04-08 | 2010-09-21 | Theta Biomedical Consulting & Development Co., Inc. | Composition for treating hormonally-dependent cancers |
US20040087613A1 (en) * | 2002-01-29 | 2004-05-06 | Molmenti Ernesto P. | Prevention of adhesions with rapamycin |
AU2003255529B2 (en) * | 2002-07-10 | 2008-11-20 | Laboratoires Serono Sa | Use of compounds for increasing spermatozoa motility |
EA011807B1 (ru) * | 2002-07-10 | 2009-06-30 | Лаборатуар Сероно Са | Азолидинонвинильные производные конденсированного бензола |
AU2003295798B2 (en) * | 2002-11-21 | 2009-09-10 | Genentech, Inc. | Therapy of non-malignant diseases or disorders with anti-ErbB2 antibodies |
WO2004056820A1 (en) * | 2002-12-20 | 2004-07-08 | Warner-Lambert Company Llc | Benzoxazines and derivatives thereof as inhibitors of pi3ks |
WO2005011686A1 (en) * | 2003-07-28 | 2005-02-10 | Applied Research Systems Ars Holding N.V. | 2-imino-4-(thio) oxo-5-poly cyclovinylazolines for use as p13 kinase ihibitors |
CA2730540A1 (en) * | 2004-05-13 | 2005-12-01 | Vanderbilt University | Phosphoinositide 3-kinase delta selective inhibitors for inhibiting angiogenesis |
MX2007001155A (es) * | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
-
2006
- 2006-08-28 US US12/066,043 patent/US20080306057A1/en not_active Abandoned
- 2006-08-28 BR BRPI0615654-1A patent/BRPI0615654A2/pt not_active IP Right Cessation
- 2006-08-28 NZ NZ565748A patent/NZ565748A/en not_active IP Right Cessation
- 2006-08-28 EP EP06813892A patent/EP1931424A2/en not_active Withdrawn
- 2006-08-28 CA CA002618489A patent/CA2618489A1/en not_active Abandoned
- 2006-08-28 WO PCT/US2006/033679 patent/WO2007030360A2/en active Application Filing
- 2006-08-28 MX MX2008003189A patent/MX2008003189A/es not_active Application Discontinuation
- 2006-08-28 EA EA200800766A patent/EA200800766A1/ru unknown
- 2006-08-28 AU AU2006287765A patent/AU2006287765B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
WO2007030360A2 (en) | 2007-03-15 |
AU2006287765B2 (en) | 2011-12-08 |
CA2618489A1 (en) | 2007-03-15 |
NZ565748A (en) | 2011-04-29 |
WO2007030360A3 (en) | 2007-05-31 |
BRPI0615654A2 (pt) | 2011-05-24 |
AU2006287765A1 (en) | 2007-03-15 |
US20080306057A1 (en) | 2008-12-11 |
EP1931424A2 (en) | 2008-06-18 |
MX2008003189A (es) | 2008-03-18 |
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