EA200501865A1 - Аналоги тиовольфраматов и их применение - Google Patents

Аналоги тиовольфраматов и их применение

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Publication number
EA200501865A1
EA200501865A1 EA200501865A EA200501865A EA200501865A1 EA 200501865 A1 EA200501865 A1 EA 200501865A1 EA 200501865 A EA200501865 A EA 200501865A EA 200501865 A EA200501865 A EA 200501865A EA 200501865 A1 EA200501865 A1 EA 200501865A1
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EA
Eurasian Patent Office
Prior art keywords
derivatives
phramate
methods
new
thiol
Prior art date
Application number
EA200501865A
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English (en)
Inventor
Роберт Дж. Тернански
Патриция Л. Глэдстоун
Эйми Л. Аллан
Мелисса Л. П. Прайс
Эндрю П. Мазар
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Атеньюон, Ллк
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Application filed by Атеньюон, Ллк filed Critical Атеньюон, Ллк
Publication of EA200501865A1 publication Critical patent/EA200501865A1/ru

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    • C01G41/006—Compounds containing, besides tungsten, two or more other elements, with the exception of oxygen or hydrogen
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    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
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    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/323—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atoms
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
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    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
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Abstract

Настоящее изобретение относится к новым тиовольфраматным производным, способам получения новых тиовольфраматных производных, фармацевтическим композициям, содержащим новые тиовольфраматные производные, способам применения новых тиовольфраматных производных для лечения заболеваний, связанных с аберрантной васкуляризацией, нарушениями обмена меди и ожирением, и способам применения фармацевтических композиций, содержащих новые тиовольфраматные производные, для лечения заболеваний, связанных с аберрантной васкуляризацией, нарушениями обмена меди, нейродегенеративньми расстройствами, ожирением и нарушением регуляции NF-κВ.
EA200501865A 2003-05-27 2004-05-27 Аналоги тиовольфраматов и их применение EA200501865A1 (ru)

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US47393703P 2003-05-27 2003-05-27
PCT/US2004/016948 WO2004110364A2 (en) 2003-05-27 2004-05-27 Thiotungstate analogues and uses thereof

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EA200501865A1 true EA200501865A1 (ru) 2006-08-25

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US (2) US7851505B2 (ru)
EP (1) EP1633310A4 (ru)
JP (1) JP2007516234A (ru)
KR (1) KR20060013561A (ru)
CN (1) CN100558409C (ru)
AU (1) AU2004247059A1 (ru)
BR (1) BRPI0410651A (ru)
CA (1) CA2527236A1 (ru)
EA (1) EA200501865A1 (ru)
IL (1) IL172195A0 (ru)
MX (1) MXPA05012722A (ru)
NO (1) NO20056116L (ru)
PL (1) PL218366B1 (ru)
WO (1) WO2004110364A2 (ru)
ZA (1) ZA200509719B (ru)

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CA2874083C (en) 2014-12-05 2024-01-02 Universite Laval Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases
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CN1832761A (zh) 2006-09-13
AU2004247059A1 (en) 2004-12-23
EP1633310A4 (en) 2006-10-18
KR20060013561A (ko) 2006-02-10
CA2527236A1 (en) 2004-12-23
MXPA05012722A (es) 2006-05-25
WO2004110364A3 (en) 2006-03-02
BRPI0410651A (pt) 2006-07-04
PL379262A1 (pl) 2006-08-07
WO2004110364A9 (en) 2005-04-07
EP1633310A2 (en) 2006-03-15
PL218366B1 (pl) 2014-11-28
ZA200509719B (en) 2007-03-28
US20110151022A1 (en) 2011-06-23
WO2004110364A2 (en) 2004-12-23
IL172195A0 (en) 2009-02-11
CN100558409C (zh) 2009-11-11
US20060160805A1 (en) 2006-07-20
US7851505B2 (en) 2010-12-14
JP2007516234A (ja) 2007-06-21
NO20056116L (no) 2006-02-24

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