EA200301079A1 - Терапевтическое средство по поводу повышенной чувствительности мочевого пузыря - Google Patents

Терапевтическое средство по поводу повышенной чувствительности мочевого пузыря

Info

Publication number
EA200301079A1
EA200301079A1 EA200301079A EA200301079A EA200301079A1 EA 200301079 A1 EA200301079 A1 EA 200301079A1 EA 200301079 A EA200301079 A EA 200301079A EA 200301079 A EA200301079 A EA 200301079A EA 200301079 A1 EA200301079 A1 EA 200301079A1
Authority
EA
Eurasian Patent Office
Prior art keywords
substituted
unsubstituted
unsubstituted lower
lower alkyl
amino
Prior art date
Application number
EA200301079A
Other languages
English (en)
Other versions
EA007069B1 (ru
Inventor
Цуйоси Ямагата
Каору Ацуки
Тецудзи Охно
Сиро Сиракура
Акира Карасава
Original Assignee
Киова Хакко Когио Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Киова Хакко Когио Ко., Лтд. filed Critical Киова Хакко Когио Ко., Лтд.
Publication of EA200301079A1 publication Critical patent/EA200301079A1/ru
Publication of EA007069B1 publication Critical patent/EA007069B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Abstract

Настоящее изобретение представляет терапевтическое средство по поводу повышенной чувствительности мочевого пузыря, включающее в качестве активного ингредиента трициклическое соединение, представленное формулой (I)[в которой Rпредставляет собой атом водорода, замещенный или незамещенный низший алкил, замещенный или незамещенный низший алкокси или галоген;X-X-Xпредставляет собой CR=CR-CR=CR, N(O)=CR-CR=CR, CR=CR-N(O)=CR, CR=CR-CR-N(O), CR=CR-O, CR=CR-S, O-CR=CR, S-CR=CRили O-CR=N;Y представляет собой -CHS-, -CHSO-, -CHSO-, -CHO-, -CH=CH-, -(CH)-, -SCH-, -SOCH-, -SOCH- или -OCH-; a Rпредставляет собой атом водорода, замещенный или незамещенный низший алкил, замещенный или незамещенный низший алкенил, замещенный или незамещенный низший алкокси, амино, моно(замещенный или незамещенный низший алкил)замещенный амино, ди(замещенный или незамещенный низший алкил)замещенный амино, замещенный или незамещенный арил, замещенный или незамещенный гетероарил, замещенный или незамещенный аралкиламино, замещенный или незамещенный ариламино или замещенную или незамещенную гетероалициклическую группу], или его фармацевтически приемлемую соль.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200301079A 2001-03-30 2002-03-29 Терапевтическое средство по поводу повышенной чувствительности мочевого пузыря EA007069B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001099800 2001-03-30
PCT/JP2002/003168 WO2002078711A1 (fr) 2001-03-30 2002-03-29 Medicaments contre l'hyperesthesie vesicale

Publications (2)

Publication Number Publication Date
EA200301079A1 true EA200301079A1 (ru) 2004-02-26
EA007069B1 EA007069B1 (ru) 2006-06-30

Family

ID=18953303

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200301079A EA007069B1 (ru) 2001-03-30 2002-03-29 Терапевтическое средство по поводу повышенной чувствительности мочевого пузыря

Country Status (12)

Country Link
US (1) US20040106671A1 (ru)
EP (1) EP1384481A1 (ru)
JP (1) JPWO2002078711A1 (ru)
KR (1) KR20040007482A (ru)
CN (1) CN1498109A (ru)
BR (1) BR0208412A (ru)
CA (1) CA2442468A1 (ru)
EA (1) EA007069B1 (ru)
HU (1) HUP0303609A3 (ru)
MX (1) MXPA03008814A (ru)
NO (1) NO20034358L (ru)
WO (1) WO2002078711A1 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2520680A1 (en) * 2003-03-31 2004-10-14 Kyowa Hakko Kogyo Co., Ltd. Antitussives
TW200501938A (en) * 2003-06-27 2005-01-16 Kyowa Hakko Kogyo Kk A medicament for therapeutic treating overactive urinary bladder accompany with cerebrovascular disorder
TW200522943A (en) * 2003-12-11 2005-07-16 Kyowa Hakko Kogyo Kk Fine crystallites and a pharmaceutical composition comprising them
TW200827367A (en) * 2006-10-26 2008-07-01 Kyowa Hakko Kogyo Kk A therapeutic agent for irritable bowel syndrome
KR100794564B1 (ko) * 2007-10-29 2008-01-17 주식회사한국사이버닉스 저온저장고용 음이온 발생장치

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ320580A (en) * 1995-10-16 1998-12-23 Kyowa Hakko Kogyo Kk Tricyclic compounds, preparation and pharmaceutical compositions thereof
KR100447674B1 (ko) * 1997-04-15 2004-09-08 교와 핫꼬 고교 가부시끼가이샤 삼환식 화합물

Also Published As

Publication number Publication date
CN1498109A (zh) 2004-05-19
EA007069B1 (ru) 2006-06-30
BR0208412A (pt) 2004-08-03
EP1384481A1 (en) 2004-01-28
MXPA03008814A (es) 2004-02-17
HUP0303609A3 (en) 2005-11-28
CA2442468A1 (en) 2002-10-10
US20040106671A1 (en) 2004-06-03
JPWO2002078711A1 (ja) 2004-07-22
NO20034358L (no) 2003-11-28
WO2002078711A1 (fr) 2002-10-10
KR20040007482A (ko) 2004-01-24
NO20034358D0 (no) 2003-09-29
HUP0303609A2 (hu) 2004-03-01

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU