EA200300880A1 - Способ детекции нуклеотидного полиморфизма - Google Patents

Способ детекции нуклеотидного полиморфизма

Info

Publication number
EA200300880A1
EA200300880A1 EA200300880A EA200300880A EA200300880A1 EA 200300880 A1 EA200300880 A1 EA 200300880A1 EA 200300880 A EA200300880 A EA 200300880A EA 200300880 A EA200300880 A EA 200300880A EA 200300880 A1 EA200300880 A1 EA 200300880A1
Authority
EA
Eurasian Patent Office
Prior art keywords
detection
nucleotide polymorphism
gene
detecting
nucleotide
Prior art date
Application number
EA200300880A
Other languages
English (en)
Other versions
EA005141B1 (ru
Inventor
Хироаки Сагава
Еидзи Кобаяси
Икуносин Като
Original Assignee
Такара Био Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Такара Био Инк. filed Critical Такара Био Инк.
Publication of EA200300880A1 publication Critical patent/EA200300880A1/ru
Publication of EA005141B1 publication Critical patent/EA005141B1/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Описывается нуклеотид, полезный для детекции замены основания в гене, способ детекции замены основания в гене с использованием указанного нуклеотида и набор для указанного способа.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200300880A 2001-02-15 2002-02-14 Способ детекции нуклеотидного полиморфизма EA005141B1 (ru)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP2001039268 2001-02-15
JP2001040721 2001-02-16
JP2001101055 2001-03-30
JP2001177381 2001-06-12
JP2001290384 2001-09-25
JP2001338440 2001-11-02
JP2001368929 2001-12-03
PCT/JP2002/001222 WO2002064833A1 (fr) 2001-02-15 2002-02-14 Procede de detection de polymorphisme de nucleotide

Publications (2)

Publication Number Publication Date
EA200300880A1 true EA200300880A1 (ru) 2004-02-26
EA005141B1 EA005141B1 (ru) 2004-12-30

Family

ID=27567022

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200300880A EA005141B1 (ru) 2001-02-15 2002-02-14 Способ детекции нуклеотидного полиморфизма

Country Status (9)

Country Link
US (1) US7135291B2 (ru)
EP (1) EP1367136A4 (ru)
JP (3) JP3681729B2 (ru)
KR (1) KR100809949B1 (ru)
CN (1) CN100351393C (ru)
AU (1) AU2002232177B2 (ru)
CA (1) CA2438574C (ru)
EA (1) EA005141B1 (ru)
WO (1) WO2002064833A1 (ru)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200404889A (en) * 2002-05-31 2004-04-01 Takara Bio Inc Method of typing gene polymorphisms
EP2292788B1 (en) * 2005-06-23 2012-05-09 Keygene N.V. Strategies for high throughput identification and detection of polymorphisms
US10227641B2 (en) 2008-04-30 2019-03-12 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
US8911948B2 (en) 2008-04-30 2014-12-16 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
US9434988B2 (en) 2008-04-30 2016-09-06 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
EP2644710B1 (en) 2008-04-30 2016-12-21 Integrated Dna Technologies, Inc. Rnase-h-based assays utilizing modified rna monomers
US10760074B2 (en) * 2008-09-03 2020-09-01 Takara Bio Inc. Composition for detection of RNA
EP2337865B1 (en) * 2008-10-20 2014-11-19 Roche Diagnostics GmbH Allele-specific amplification using a primer with a modified nucleotide
WO2011060014A1 (en) * 2009-11-13 2011-05-19 Integrated Dna Technologies, Inc. Small rna detection assays
US8614071B2 (en) 2009-12-11 2013-12-24 Roche Molecular Systems, Inc. Preferential amplification of mRNA over DNA using chemically modified primers
US9238832B2 (en) 2009-12-11 2016-01-19 Roche Molecular Systems, Inc. Allele-specific amplification of nucleic acids
JP6466173B2 (ja) 2012-02-14 2019-02-06 ヴェラ オペレーションズ ユーエスエー,インコーポレーテッド ブロック型プライマーを用いた等温増幅法
KR102126744B1 (ko) 2013-03-14 2020-06-26 다카라 바이오 가부시키가이샤 내열성 미스매치 엔도뉴클레아제의 이용방법
AU2013381709A1 (en) * 2013-03-15 2015-10-01 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
EP3068876B1 (en) 2013-11-14 2019-05-08 Integrated DNA Technologies Inc. Dna polymerase mutants having enhanced template discrimination activity
US11060149B2 (en) 2014-06-18 2021-07-13 Clear Gene, Inc. Methods, compositions, and devices for rapid analysis of biological markers
WO2016039377A1 (ja) 2014-09-11 2016-03-17 タカラバイオ株式会社 耐熱性のミスマッチエンドヌクレアーゼの利用方法
US9909169B2 (en) 2014-12-17 2018-03-06 Roche Molecular Systems, Inc. Allele-specific amplification of nucleic acids using blocking oligonucleotides for wild type suppression
US20180163263A1 (en) * 2015-03-20 2018-06-14 Takara Bio Inc. High-sensitivity method for detecting target nucleic acid
AU2016369603A1 (en) 2015-12-18 2018-07-05 Clear Gene, Inc. Methods, compositions, kits and devices for rapid analysis of biological markers
CN108148895A (zh) * 2017-12-29 2018-06-12 星阵(广州)基因科技有限公司 用于检测突变的人akt1基因的引物、试剂盒及方法
CN113215163B (zh) * 2021-05-12 2023-05-12 苏州海苗生物科技有限公司 一种特异性扩增目的基因的分子锁及应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4521509A (en) * 1982-11-24 1985-06-04 Research Corporation Method for degrading DNA
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5011769A (en) * 1985-12-05 1991-04-30 Meiogenics U.S. Limited Partnership Methods for detecting nucleic acid sequences
US4876187A (en) 1985-12-05 1989-10-24 Meiogenics, Inc. Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
CA1340807C (en) 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process
JP2650159B2 (ja) 1988-02-24 1997-09-03 アクゾ・ノベル・エヌ・ベー 核酸増幅方法
US5639611A (en) * 1988-12-12 1997-06-17 City Of Hope Allele specific polymerase chain reaction
US5137806A (en) 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US5455166A (en) 1991-01-31 1995-10-03 Becton, Dickinson And Company Strand displacement amplification
US5846717A (en) 1996-01-24 1998-12-08 Third Wave Technologies, Inc. Detection of nucleic acid sequences by invader-directed cleavage
WO1995014106A2 (en) 1993-11-17 1995-05-26 Id Biomedical Corporation Cycling probe cleavage detection of nucleic acid sequences
ES2165402T3 (es) 1994-07-16 2002-03-16 Roche Diagnostics Gmbh Procedimiento para la deteccion sensible de acidos nucleicos.
JP3665648B2 (ja) * 1996-01-24 2005-06-29 サード ウェーブ テクノロジーズ,インコーポレーテッド 核酸の侵入的開裂
NL1002427C2 (nl) * 1996-02-23 1997-08-26 Akzo Nobel Nv Bekledingssamenstelling omvattende een bicyclo- of spiroorthoester functionele verbinding.
US5808108A (en) * 1997-01-15 1998-09-15 Chappelow; Cecil C. Polymeric compositions and composites prepared from spiroorthocarbonates and epoxy monomers
DE19733619C1 (de) 1997-08-04 2000-02-24 Markus Schuermann CASE-PCR, ein hochselektives Verfahren zum Nachweis von Onkogenmutationen und Allelvarianten
EA005577B1 (ru) 1999-03-19 2005-04-28 Такара Био Инк. Продукт, содержащий иммобилизованную нуклеиновую кислоту, полученный способом с участием химерного олигонуклеотидного праймера, днк-полимеразы и эндонуклеазы
GB9915200D0 (en) * 1999-06-29 1999-09-01 Janssen Pharmaceutica Nv Neurotrophic factor receptor
NZ516894A (en) 1999-07-02 2004-06-25 Invitrogen Corp Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis
GB9918150D0 (en) 1999-08-03 1999-10-06 Univ Sheffield Nuclease variant
US6274353B1 (en) 1999-09-22 2001-08-14 Genecopoeia, Inc. Method and compositions for improved polynucleotide synthesis
JP2001136965A (ja) * 1999-11-12 2001-05-22 Takara Shuzo Co Ltd 核酸配列の増幅方法
WO2001042498A1 (fr) 1999-12-10 2001-06-14 Toyo Boseki Kabushiki Kaisha Procede de detection de polymorphisme nucleotidique
EP1356094B1 (en) 2000-06-26 2010-01-13 Nugen Technologies, Inc. Methods and compositions for transcription-based nucleic acid amplification
US6773885B1 (en) * 2000-09-29 2004-08-10 Integrated Dna Technologies, Inc. Compositions and methods for visual ribonuclease detection assays
WO2002063049A2 (en) * 2001-02-02 2002-08-15 Genome Therapeutics Corporation Methods for determining a nucleotide at a specific location within a nucleic acid molecule
US7163790B2 (en) * 2001-11-28 2007-01-16 Bio-Rad Laboratories, Inc. Parallel polymorphism scoring by amplification and error correction

Also Published As

Publication number Publication date
US20040137451A1 (en) 2004-07-15
CN1524127A (zh) 2004-08-25
EA005141B1 (ru) 2004-12-30
EP1367136A4 (en) 2005-01-12
CA2438574A1 (en) 2002-08-22
JP2005245465A (ja) 2005-09-15
KR20030074797A (ko) 2003-09-19
KR100809949B1 (ko) 2008-03-06
EP1367136A1 (en) 2003-12-03
WO2002064833A1 (fr) 2002-08-22
CN100351393C (zh) 2007-11-28
CA2438574C (en) 2009-08-11
JPWO2002064833A1 (ja) 2004-06-17
US7135291B2 (en) 2006-11-14
AU2002232177B2 (en) 2006-11-09
JP2004298200A (ja) 2004-10-28
JP3681729B2 (ja) 2005-08-10

Similar Documents

Publication Publication Date Title
EA200300880A1 (ru) Способ детекции нуклеотидного полиморфизма
DE602004001227D1 (de) Nukleinsäure-biosensor
DE60300734D1 (de) Anordnungen zur Vorbehandlung von Proben
UA84284C2 (ru) Способы лечения, профилактики и диагностики инфекции helicobacter cerdo
ATE490466T1 (de) Als interne funktionskontrolle in tests zum nachweis von seltenen zellen verwendete markierte zellen
HK1120568A1 (en) Biosensors for detecting macromolecules and other analytes
DK1409984T4 (da) Fremgangsmåder og reagenser til detektering af endotoxin
HK1054980A1 (zh) 利用肝臟干細胞進行毒性分型
ATE480642T1 (de) Verfahren zur bestimmung von genotoxizität
DE60330842D1 (de) Für den nachweis von nukleinsäuren kompetente biologische rohderivate
ATE456666T1 (de) Verfahren zur auswertung von ribonukleotidsequenzen
ATE336591T1 (de) Nachweisverfahren für kurze sequenzvarianten
EA200500355A1 (ru) Способ обнаружения, характеристики и мониторинга углеводородных месторождений
NO20052553L (no) Cobalaminanalyse.
ITTO20020117A0 (it) Apparecchiatura per prove tribologiche.
DE60309785D1 (de) Reagenzien-Kit zum Nachweis von Lupus-Antikoagulant
EA200200435A1 (ru) Анализ лептина
DK1689886T3 (da) Molekylær markör associeret med CMV-resistens og anvendelse deraf
ITMI20031619A1 (it) Amplificatore di rilevamento perfezionato.
WO2004000995A3 (en) Methods, probes, and accessory molecules for detecting single nucleotide polymorphisms
EA200200798A1 (ru) Кальцилитические соединения
WO2005001129A3 (en) Mobility cassettes
WO2005014847A3 (en) Reagents, methods and kits for detecting feed enzymes
DE10256898A8 (de) Elektrochemischer Nachweis von Nukleinsäuren
DE60327776D1 (de) Sonden zum nachweis von tumorzellen

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM