EA200200042A1 - Стабильный раствор ксилометазолина и оксиметазолина - Google Patents

Стабильный раствор ксилометазолина и оксиметазолина

Info

Publication number
EA200200042A1
EA200200042A1 EA200200042A EA200200042A EA200200042A1 EA 200200042 A1 EA200200042 A1 EA 200200042A1 EA 200200042 A EA200200042 A EA 200200042A EA 200200042 A EA200200042 A EA 200200042A EA 200200042 A1 EA200200042 A1 EA 200200042A1
Authority
EA
Eurasian Patent Office
Prior art keywords
stable solution
oximetasoline
xylomethazoline
xylometazoline
oxymetazoline
Prior art date
Application number
EA200200042A
Other languages
English (en)
Other versions
EA003329B1 (ru
Inventor
Фридер Ульрих Мэрц
Original Assignee
Бёрингер Ингельхайм Интернациональ Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23322017&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200200042(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Бёрингер Ингельхайм Интернациональ Гмбх filed Critical Бёрингер Ингельхайм Интернациональ Гмбх
Publication of EA200200042A1 publication Critical patent/EA200200042A1/ru
Publication of EA003329B1 publication Critical patent/EA003329B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/38—Silver; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

В заявке описан биологически и химически стабильный раствор ксилометазолина и/или оксиметазолина с глицерином и/или сорбитом в качестве адъюванта.Отчет о международном поиске был опубликован 2001.03.01.
EA200200042A 1999-06-22 2000-06-17 Стабильный раствор ксилометазолина и оксиметазолина EA003329B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33778999A 1999-06-22 1999-06-22
PCT/EP2000/005583 WO2000078297A2 (de) 1999-06-22 2000-06-17 Stabile xylometazolin- und oxymetazolinlösung

Publications (2)

Publication Number Publication Date
EA200200042A1 true EA200200042A1 (ru) 2002-06-27
EA003329B1 EA003329B1 (ru) 2003-04-24

Family

ID=23322017

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200042A EA003329B1 (ru) 1999-06-22 2000-06-17 Стабильный раствор ксилометазолина и оксиметазолина

Country Status (22)

Country Link
US (2) US20040191177A1 (ru)
EP (1) EP1194145B1 (ru)
JP (1) JP2003502361A (ru)
KR (1) KR20020012001A (ru)
CN (1) CN1164271C (ru)
AT (1) ATE232099T1 (ru)
AU (1) AU765736B2 (ru)
BR (1) BR0011950A (ru)
CA (1) CA2376121C (ru)
CZ (1) CZ295595B6 (ru)
DE (1) DE50001217D1 (ru)
EA (1) EA003329B1 (ru)
ES (1) ES2188563T3 (ru)
HK (1) HK1045945B (ru)
HU (1) HUP0201700A3 (ru)
IL (1) IL147023A0 (ru)
MX (1) MXPA01012912A (ru)
PL (1) PL197542B1 (ru)
PT (1) PT1194145E (ru)
TR (1) TR200103694T2 (ru)
WO (1) WO2000078297A2 (ru)
ZA (1) ZA200110386B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1446119T1 (sl) 2001-09-18 2006-08-31 Nycomed Danmark Aps Sestavki, ki obsegajo ipratorij in ksilometazolin, za zdravljenje obicajnega prehlada
CA2489528A1 (en) * 2002-06-20 2003-12-31 Novartis Consumer Health S.A. Nasal compositions comprising a mucopolysaccharide and propylene glycol
US7714011B2 (en) * 2002-09-13 2010-05-11 Zicam, Llc Compositions to reduce congestion and methods for application thereof to the nasal membrane
DE10337186A1 (de) * 2003-08-13 2005-03-17 Merck Patent Gmbh Wässrige Wirkstoff-Lösung
US20090136598A1 (en) * 2006-04-26 2009-05-28 Aciex, Inc. Compositions for the Treatment and Prevention of Eyelid Swelling
AU2007243334A1 (en) * 2006-04-26 2007-11-08 Aciex Therapeutics, Inc. Compositions for the treatment and prevention of eyelid swelling
CN101912363A (zh) * 2010-07-29 2010-12-15 蔡海德 溶解超滤-喷雾干燥-分子分散包衣-水化制粒-冷冻干燥生产脂质体组合药物
KR20170094791A (ko) 2014-12-24 2017-08-21 자드란 - 갈렌스키 라보라토리 디.디. 안정성-개선 부형제로서 해수를 함유하는 비강 조성물
WO2023046590A1 (en) 2021-09-22 2023-03-30 Jadran - Galenski Laboratorij D.D. An improved pharmaceutical composition for nasal use, preparation, and use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603131A (en) * 1982-04-26 1986-07-29 Bernstein Joel E Method and composition for treating and preventing irritation of the mucous membranes of the nose
US5114979A (en) * 1989-10-18 1992-05-19 Schering Corporation Fruity flavored nasal decongestant composition
US4970240A (en) * 1989-10-18 1990-11-13 Schering Corporation Fruity flavored nasal decongestant composition
US5540930A (en) * 1993-10-25 1996-07-30 Pharmos Corporation Suspension of loteprednol etabonate for ear, eye, or nose treatment
DE19549421C2 (de) * 1995-11-10 1999-11-18 Klosterfrau Mcm Vetrieb Gmbh Pharmazeutische Zubereitung zur Behandlung akuter Rhinitiden
DE19542959C1 (de) * 1995-11-17 1996-10-24 Ursatec Verpackung Gmbh Vor Kontamination schützende Abgabevorrichtung für Fluide
EP0861128B1 (de) * 1995-11-17 2003-02-19 Ursatec Verpackung Gmbh Vor kontamination schützende abgabevorrichtung für fluide
PT1051155E (pt) * 1998-01-30 2002-10-31 Novartis Consumer Health Sa Solucoes nasais

Also Published As

Publication number Publication date
WO2000078297A2 (de) 2000-12-28
HK1045945A1 (en) 2002-12-20
DE50001217D1 (de) 2003-03-13
CZ295595B6 (cs) 2005-08-17
JP2003502361A (ja) 2003-01-21
US20040191177A1 (en) 2004-09-30
EP1194145A2 (de) 2002-04-10
PL197542B1 (pl) 2008-04-30
HUP0201700A2 (hu) 2002-12-28
US20080011293A1 (en) 2008-01-17
HK1045945B (zh) 2005-01-28
AU765736B2 (en) 2003-09-25
AU6150600A (en) 2001-01-09
CA2376121C (en) 2008-06-10
PT1194145E (pt) 2003-06-30
CZ20014568A3 (cs) 2002-03-13
PL352354A1 (en) 2003-08-11
CN1361689A (zh) 2002-07-31
WO2000078297A3 (de) 2001-03-01
ZA200110386B (en) 2003-04-22
BR0011950A (pt) 2002-03-12
TR200103694T2 (tr) 2002-04-22
KR20020012001A (ko) 2002-02-09
HUP0201700A3 (en) 2003-02-28
ATE232099T1 (de) 2003-02-15
ES2188563T3 (es) 2003-07-01
EA003329B1 (ru) 2003-04-24
MXPA01012912A (es) 2002-09-18
IL147023A0 (en) 2002-08-14
EP1194145B1 (de) 2003-02-05
CN1164271C (zh) 2004-09-01
CA2376121A1 (en) 2000-12-28

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY KZ RU