EA199800676A1 - Способы повышения компетенции сфинктера - Google Patents

Способы повышения компетенции сфинктера

Info

Publication number
EA199800676A1
EA199800676A1 EA199800676A EA199800676A EA199800676A1 EA 199800676 A1 EA199800676 A1 EA 199800676A1 EA 199800676 A EA199800676 A EA 199800676A EA 199800676 A EA199800676 A EA 199800676A EA 199800676 A1 EA199800676 A1 EA 199800676A1
Authority
EA
Eurasian Patent Office
Prior art keywords
competence
sphinkter
ways
improve
person
Prior art date
Application number
EA199800676A
Other languages
English (en)
Other versions
EA001103B1 (ru
Inventor
Джордж Дж. Каллинан
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603147.1A external-priority patent/GB9603147D0/en
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA199800676A1 publication Critical patent/EA199800676A1/ru
Publication of EA001103B1 publication Critical patent/EA001103B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Способ повышения компетенции сфинктера, включающий введение человеку, нуждающемуся в таком лечении, эффективного количества соединения формулы I, где Rи Rнезависимо являются водородом, -СН, (а) или (b), где Ar является необязательно замещенным фенилом; Rвыбирают из группы, состоящей из пирролидино, гексаметиленимино и пиперидино; или его фармацевтически приемлемой соли или сольвата. Изобретение также включает способ ингибирования недержания мочи или кала или гастроэзофагеального расстройства или его симптомов, который включает введение человеку, нуждающемуся в этом, эффективного количества соединения формулы (I).Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199800676A 1996-01-29 1997-01-27 Способы повышения компетенции сфинктера EA001103B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1077196P 1996-01-29 1996-01-29
GBGB9603147.1A GB9603147D0 (en) 1996-02-15 1996-02-15 Methods of increasing sphincter competence
PCT/US1997/001159 WO1997026876A1 (en) 1996-01-29 1997-01-27 Methods of increasing sphincter competence

Publications (2)

Publication Number Publication Date
EA199800676A1 true EA199800676A1 (ru) 1999-02-25
EA001103B1 EA001103B1 (ru) 2000-10-30

Family

ID=26308706

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199800676A EA001103B1 (ru) 1996-01-29 1997-01-27 Способы повышения компетенции сфинктера

Country Status (11)

Country Link
EP (1) EP0910378A4 (ru)
JP (1) JP2000503991A (ru)
CN (1) CN1213303A (ru)
AU (1) AU732473B2 (ru)
CZ (1) CZ235598A3 (ru)
EA (1) EA001103B1 (ru)
HU (1) HUP9903440A3 (ru)
IL (1) IL125522A0 (ru)
NO (1) NO983453L (ru)
NZ (1) NZ331085A (ru)
WO (1) WO1997026876A1 (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1113007A1 (en) 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
WO2002003989A2 (en) * 2000-07-06 2002-01-17 Wyeth Use of substituted indole compounds for treating sphincter incontinence
US6376486B1 (en) 2000-07-06 2002-04-23 American Home Products Corporation Methods of inhibiting sphincter incontinence
US6455568B2 (en) 2000-07-06 2002-09-24 Wyeth Combination therapy for inhibiting sphincter incontinence
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
KR101505884B1 (ko) 2006-05-22 2015-03-25 호르모스 메디칼 리미티드 만성 비세균성 전립선염 치료용 선택적 에스트로겐 수용체 조절제 또는 아로마타아제 저해제

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5391557A (en) * 1993-10-15 1995-02-21 Eli Lilly And Company Methods for the treatment of peri-menopausal syndrome
US5492927A (en) * 1993-12-21 1996-02-20 Eli Lilly And Company Non-peptide tachykinin receptor antagonists to treat allergy
US6562862B1 (en) * 1994-10-20 2003-05-13 Eli Lilly And Company Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y
AU3899595A (en) * 1994-12-02 1996-06-19 Mostyn Farmer Golf stance training aid
US5789442A (en) * 1996-01-18 1998-08-04 Schering Aktiengesellschaft Treatment of urinary incontinence with nitric oxide synthase substrates and/or nitric oxide donors alone or in combination with estrogen or progesterone and/or other agents

Also Published As

Publication number Publication date
HUP9903440A2 (hu) 2000-06-28
HUP9903440A3 (en) 2000-07-28
WO1997026876A1 (en) 1997-07-31
NO983453L (no) 1998-09-11
EP0910378A1 (en) 1999-04-28
EP0910378A4 (en) 1999-06-23
EA001103B1 (ru) 2000-10-30
IL125522A0 (en) 1999-03-12
NO983453D0 (no) 1998-07-27
AU1838697A (en) 1997-08-20
CZ235598A3 (cs) 1999-03-17
AU732473B2 (en) 2001-04-26
CN1213303A (zh) 1999-04-07
NZ331085A (en) 2000-06-23
JP2000503991A (ja) 2000-04-04

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU