EA199800288A1 - Производные 5-o-дезозаминил-6-o-метилэритронолида а, способ их получения и их применение для получения биологически активных продуктов - Google Patents

Производные 5-o-дезозаминил-6-o-метилэритронолида а, способ их получения и их применение для получения биологически активных продуктов

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Publication number
EA199800288A1
EA199800288A1 EA199800288A EA199800288A EA199800288A1 EA 199800288 A1 EA199800288 A1 EA 199800288A1 EA 199800288 A EA199800288 A EA 199800288A EA 199800288 A EA199800288 A EA 199800288A EA 199800288 A1 EA199800288 A1 EA 199800288A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methyleritronolid
deozominil
derivatives
application
production
Prior art date
Application number
EA199800288A
Other languages
English (en)
Other versions
EA000575B1 (ru
Inventor
Алан Бонне
Мишель Дельтиль
Алан Мазюри
Original Assignee
Хехст Марион Руссель
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9482423&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA199800288(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Хехст Марион Руссель filed Critical Хехст Марион Руссель
Publication of EA199800288A1 publication Critical patent/EA199800288A1/ru
Publication of EA000575B1 publication Critical patent/EA000575B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

Объектом настоящего изобретения являются соединения формулы (I), в которых OR, ORи ORпредставляют гидроксильные радикалы, блокированные в форме легко расщепляемых радикалов. Соединения формулы (I) могут быть использованы для получения антибиотических продуктов.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199800288A 1995-09-11 1996-09-10 Производные 5-0-дезозаминил-6-0-метилэритронолида а, способ их получения и их применение для получения биологически активных продуктов EA000575B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9510601A FR2738571B1 (fr) 1995-09-11 1995-09-11 Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
PCT/FR1996/001384 WO1997010251A1 (fr) 1995-09-11 1996-09-10 Nouveaux derives de la 5-0-desosaminyl 6-0-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs

Publications (2)

Publication Number Publication Date
EA199800288A1 true EA199800288A1 (ru) 1998-08-27
EA000575B1 EA000575B1 (ru) 1999-12-29

Family

ID=9482423

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199800288A EA000575B1 (ru) 1995-09-11 1996-09-10 Производные 5-0-дезозаминил-6-0-метилэритронолида а, способ их получения и их применение для получения биологически активных продуктов

Country Status (34)

Country Link
US (1) US5969161A (ru)
EP (1) EP0854880B1 (ru)
JP (1) JP4332218B2 (ru)
KR (1) KR100457755B1 (ru)
CN (2) CN1237069C (ru)
AP (1) AP887A (ru)
AR (1) AR004195A1 (ru)
AT (1) ATE266035T1 (ru)
AU (1) AU708811B2 (ru)
BG (1) BG63822B1 (ru)
BR (1) BR9610503A (ru)
CA (1) CA2228670C (ru)
CZ (3) CZ294865B6 (ru)
DE (1) DE69632405T2 (ru)
DK (1) DK0854880T3 (ru)
EA (1) EA000575B1 (ru)
EE (1) EE03774B1 (ru)
ES (1) ES2219698T3 (ru)
FR (1) FR2738571B1 (ru)
GE (1) GEP20022838B (ru)
HK (2) HK1016187A1 (ru)
HU (1) HU227565B1 (ru)
IL (1) IL123550A (ru)
MX (1) MX9801859A (ru)
NO (2) NO312678B1 (ru)
PL (1) PL183652B1 (ru)
PT (1) PT854880E (ru)
RO (1) RO120137B1 (ru)
SI (1) SI0854880T1 (ru)
SK (3) SK285853B6 (ru)
TR (1) TR199800438T1 (ru)
UA (1) UA53628C2 (ru)
WO (1) WO1997010251A1 (ru)
ZA (1) ZA966837B (ru)

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KR100523679B1 (ko) * 1996-09-04 2005-10-26 아보트 러보러터리즈 항균 활성을 지닌 6-ｏ-치환된 케톨라이드
UA51730C2 (ru) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-0-замещённые кетолиды с антибактериальной активностью
US6034069A (en) * 1997-09-30 2000-03-07 Abbott Laboratories 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
US6124269A (en) * 1997-10-29 2000-09-26 Abbott Laboratories 2-Halo-6-O-substituted ketolide derivatives
US6046171A (en) * 1997-10-29 2000-04-04 Abbott Laboratories 6,11-bridged erythromycin derivatives
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
US6420535B1 (en) 1999-06-07 2002-07-16 Abbott Laboratories 6-O-carbamate ketolide derivatives
US20050171342A1 (en) * 2002-02-15 2005-08-04 Michael Burnet Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
US7273853B2 (en) * 2002-05-13 2007-09-25 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US6753318B1 (en) 2002-07-25 2004-06-22 Enanta Pharmaceuticals, Inc. 6,11-4-carbon bridged erythromycin derivatives
US6841664B2 (en) * 2002-07-25 2005-01-11 Enanra Pharmaceuticals, Inc. 6,11-4-carbon bridged ketolides
WO2005070918A1 (en) * 2002-05-13 2005-08-04 Enanta Pharmaceuticals, Inc. Process for the preparation of t-11 bicyclic erythromycin derivatives
US7064110B2 (en) * 2002-05-13 2006-06-20 Enanta Pharmaceuticals, Inc. 6-11 bicycle ketolide derivatives
US7910558B2 (en) * 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US6878691B2 (en) * 2002-05-13 2005-04-12 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
CN1659178A (zh) * 2002-05-13 2005-08-24 英安塔制药有限公司 6、11二环红霉素衍生物
US7135573B2 (en) * 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
ITMI20021726A1 (it) * 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
US6645941B1 (en) 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
US7276487B2 (en) * 2003-09-23 2007-10-02 Enanta Pharmaceuticals, Inc. 9a, 11-3C-bicyclic 9a-azalide derivatives
US7414030B2 (en) 2004-01-07 2008-08-19 Enanta Pharmaceuticals, Inc. 6-11 Bicyclic erythromycin derivatives
WO2005070113A2 (en) * 2004-01-09 2005-08-04 Enanta Pharmaceuticals, Inc. 9n-substituted 6-11 bicyclic erythromycin derivatives
US7419962B2 (en) 2004-12-07 2008-09-02 Enanta Pharmaceuticals, Inc. 3,6-bicyclolides
US7229972B2 (en) 2004-12-07 2007-06-12 Enanta Pharmaceuticals, Inc. 3,6-Bicyclolides
TW200635600A (en) 2004-12-13 2006-10-16 Enanta Pharm Inc Tetracyclic bicyclolides
WO2006065721A2 (en) 2004-12-13 2006-06-22 Enanta Pharmaceuticals, Inc. 11, 12-lactone bicyclolides
US7384922B2 (en) * 2005-05-04 2008-06-10 Enanta Pharmaceuticals, Inc. 6-11 bridged oxime erythromycin derivatives
WO2007012464A1 (en) * 2005-07-26 2007-02-01 Merckle Gmbh Macrolide conjugates of pyrrolizine and indolizine compounds as inhibitors of 5-lipooxygenase and cyclooxygenase
CN101855219B (zh) * 2007-09-17 2014-06-25 英安塔制药有限公司 6，11-桥联的联芳大环内酯类
US8273720B2 (en) * 2007-09-17 2012-09-25 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl macrolide derivatives
US8354383B2 (en) * 2007-09-17 2013-01-15 Enanta Pharmaceuticals, Inc. 6,11-bridged biaryl macrolides
CN103232501A (zh) * 2013-04-11 2013-08-07 宜昌东阳光药业股份有限公司 阿奇霉素或阿奇霉素的中间体脱去克拉定糖化合物的制备工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
US5523399A (en) * 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives

Also Published As

Publication number Publication date
HK1041489A1 (en) 2002-07-12
DE69632405D1 (de) 2004-06-09
FR2738571B1 (fr) 1997-10-17
ES2219698T3 (es) 2004-12-01
EA000575B1 (ru) 1999-12-29
EE03774B1 (et) 2002-06-17
CN1237069C (zh) 2006-01-18
UA53628C2 (ru) 2003-02-17
SK285995B6 (sk) 2008-01-07
RO120137B1 (ro) 2005-09-30
NO20021111L (no) 1998-03-10
CN1070498C (zh) 2001-09-05
ZA966837B (en) 1997-08-13
PT854880E (pt) 2004-09-30
AU708811B2 (en) 1999-08-12
PL326274A1 (en) 1998-08-31
JPH11512416A (ja) 1999-10-26
KR19990044543A (ko) 1999-06-25
CZ71798A3 (cs) 1998-07-15
BG63822B1 (bg) 2003-02-28
NO981053L (no) 1998-03-10
HU227565B1 (en) 2011-08-29
SK283690B6 (sk) 2003-12-02
EP0854880A1 (fr) 1998-07-29
ATE266035T1 (de) 2004-05-15
US5969161A (en) 1999-10-19
KR100457755B1 (ko) 2005-02-28
EP0854880B1 (fr) 2004-05-06
CZ294866B6 (cs) 2005-04-13
CA2228670A1 (fr) 1997-03-20
CN1201462A (zh) 1998-12-09
PL183652B1 (pl) 2002-06-28
CZ294865B6 (cs) 2005-04-13
HK1041489B (zh) 2006-09-08
SK285853B6 (sk) 2007-09-06
DE69632405T2 (de) 2005-05-19
IL123550A0 (en) 1998-10-30
HUP9802930A3 (en) 1999-12-28
NO20021111D0 (no) 2002-03-06
TR199800438T1 (xx) 1998-05-21
CZ289945B6 (cs) 2002-04-17
WO1997010251A1 (fr) 1997-03-20
GEP20022838B (en) 2002-11-25
HUP9802930A1 (hu) 1999-04-28
AP887A (en) 2000-11-10
NO981053D0 (no) 1998-03-10
NO315048B1 (no) 2003-06-30
JP4332218B2 (ja) 2009-09-16
AP9801210A0 (en) 1998-03-31
FR2738571A1 (fr) 1997-03-14
HK1016187A1 (en) 1999-10-29
CA2228670C (fr) 2005-04-12
CN1319602A (zh) 2001-10-31
BR9610503A (pt) 1999-07-06
SK29498A3 (en) 1998-12-02
DK0854880T3 (da) 2004-08-16
AR004195A1 (es) 1998-11-04
NO312678B1 (no) 2002-06-17
BG102312A (en) 1998-09-30
AU6991096A (en) 1997-04-01
EE9800065A (et) 1998-08-17
MX9801859A (es) 1998-11-30
IL123550A (en) 2002-09-12
SI0854880T1 (en) 2004-12-31

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