EA199800274A1 - Способ получения бензилзамещенных производных роданина - Google Patents

Способ получения бензилзамещенных производных роданина

Info

Publication number
EA199800274A1
EA199800274A1 EA199800274A EA199800274A EA199800274A1 EA 199800274 A1 EA199800274 A1 EA 199800274A1 EA 199800274 A EA199800274 A EA 199800274A EA 199800274 A EA199800274 A EA 199800274A EA 199800274 A1 EA199800274 A1 EA 199800274A1
Authority
EA
Eurasian Patent Office
Prior art keywords
rodanin
substituted
substituted derivatives
benzyl
producing benzene
Prior art date
Application number
EA199800274A
Other languages
English (en)
Other versions
EA000663B1 (ru
Inventor
Джеймс Д. Копп
Фрэнсис О. Гинах
Марвин М. Хансен
Дуглас П. Кжелл
Брайан Дж. Слэттери
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of EA199800274A1 publication Critical patent/EA199800274A1/ru
Publication of EA000663B1 publication Critical patent/EA000663B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40—Y being a hydrogen or a carbon atom
    • C07C323/41—Y being a hydrogen or an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Данное изобретение касается нового способа получения бензилзамещенных производных роданина. Кроме того, оно касается новых бензилзамещенных тиоламидов и бензилзамещенных гемитиоацеталей (полутиоацеталей). Такие соединения используются в качестве промежуточных при получении соединений по способу данного изобретения.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199800274A 1995-09-07 1996-09-03 Способ получения бензил-замещенных производных роданина EA000663B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US334395P 1995-09-07 1995-09-07
PCT/US1996/014101 WO1997009305A1 (en) 1995-09-07 1996-09-03 Process for preparing benzyl-substituted rhodanine derivatives

Publications (2)

Publication Number Publication Date
EA199800274A1 true EA199800274A1 (ru) 1998-08-27
EA000663B1 EA000663B1 (ru) 1999-12-29

Family

ID=21705388

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199800274A EA000663B1 (ru) 1995-09-07 1996-09-03 Способ получения бензил-замещенных производных роданина

Country Status (25)

Country Link
EP (1) EP0761657B1 (ru)
JP (1) JPH11514977A (ru)
KR (1) KR19990044421A (ru)
CN (1) CN1073094C (ru)
AT (1) ATE193284T1 (ru)
AU (1) AU704720B2 (ru)
BR (1) BR9610392A (ru)
CA (1) CA2230993A1 (ru)
CZ (1) CZ67998A3 (ru)
DE (1) DE69608512T2 (ru)
DK (1) DK0761657T3 (ru)
EA (1) EA000663B1 (ru)
ES (1) ES2146837T3 (ru)
GR (1) GR3034157T3 (ru)
HK (1) HK1013821A1 (ru)
HU (1) HUP9901670A3 (ru)
IL (1) IL123559A0 (ru)
NO (1) NO309604B1 (ru)
NZ (1) NZ316799A (ru)
PL (1) PL325473A1 (ru)
PT (1) PT761657E (ru)
SG (1) SG84520A1 (ru)
SI (1) SI0761657T1 (ru)
TR (2) TR199800381T1 (ru)
WO (1) WO1997009305A1 (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1210933A4 (en) * 1999-09-07 2003-01-22 Soken Kk SKIN CARE AGENTS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL79648A (en) * 1985-08-09 1991-12-12 Lilly Co Eli Pharmaceutical anti-inflammatory and ischemia preventing compositions containing di-t-butylphenol derivatives,some such novel compounds and process for their preparation
US5216002A (en) * 1989-12-21 1993-06-01 Eli Lilly And Company Method of treating inflammatory bowel disease
ZA9010041B (en) * 1989-12-21 1992-08-26 Lilly Co Eli Compounds for treating inflammatory bowel disease
US5563277A (en) * 1994-12-21 1996-10-08 Eli Lilly And Company Process for preparing benzyl-substituted rhodanine derivatives

Also Published As

Publication number Publication date
SG84520A1 (en) 2001-11-20
DK0761657T3 (da) 2000-08-14
GR3034157T3 (en) 2000-11-30
NO980937L (no) 1998-03-04
TR199800381T1 (xx) 1998-05-21
PL325473A1 (en) 1998-07-20
TR199903176T2 (xx) 2000-03-21
EP0761657B1 (en) 2000-05-24
CN1073094C (zh) 2001-10-17
HUP9901670A2 (hu) 1999-09-28
DE69608512T2 (de) 2001-01-25
AU704720B2 (en) 1999-04-29
KR19990044421A (ko) 1999-06-25
DE69608512D1 (de) 2000-06-29
HK1013821A1 (en) 1999-09-10
EA000663B1 (ru) 1999-12-29
NZ316799A (en) 1999-11-29
EP0761657A1 (en) 1997-03-12
CN1201451A (zh) 1998-12-09
CZ67998A3 (cs) 1998-08-12
ATE193284T1 (de) 2000-06-15
PT761657E (pt) 2000-11-30
ES2146837T3 (es) 2000-08-16
WO1997009305A1 (en) 1997-03-13
JPH11514977A (ja) 1999-12-21
HUP9901670A3 (en) 2001-02-28
IL123559A0 (en) 1998-10-30
NO309604B1 (no) 2001-02-26
SI0761657T1 (en) 2000-10-31
BR9610392A (pt) 1999-07-06
MX9801756A (es) 1998-08-30
CA2230993A1 (en) 1997-03-13
AU6911396A (en) 1997-03-27
NO980937D0 (no) 1998-03-04

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU