EA029305B1 - Составы дезоксихолевой кислоты и ее солей - Google Patents

Составы дезоксихолевой кислоты и ее солей Download PDF

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Publication number
EA029305B1
EA029305B1 EA201490175A EA201490175A EA029305B1 EA 029305 B1 EA029305 B1 EA 029305B1 EA 201490175 A EA201490175 A EA 201490175A EA 201490175 A EA201490175 A EA 201490175A EA 029305 B1 EA029305 B1 EA 029305B1
Authority
EA
Eurasian Patent Office
Prior art keywords
composition
sodium
approximately
sodium deoxycholate
salt
Prior art date
Application number
EA201490175A
Other languages
English (en)
Russian (ru)
Other versions
EA201490175A1 (ru
Inventor
Роберт Эмил Ходж
Джеффри Дуглас Вебстер
Роберт М. Мориарти
Original Assignee
Китера Биофармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45569726&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA029305(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Китера Биофармасьютикалз, Инк. filed Critical Китера Биофармасьютикалз, Инк.
Publication of EA201490175A1 publication Critical patent/EA201490175A1/ru
Publication of EA029305B1 publication Critical patent/EA029305B1/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
EA201490175A 2011-08-23 2011-08-23 Составы дезоксихолевой кислоты и ее солей EA029305B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/048806 WO2013028177A1 (fr) 2011-08-23 2011-08-23 Préparations d'acide désoxycholique et sels associés

Publications (2)

Publication Number Publication Date
EA201490175A1 EA201490175A1 (ru) 2014-06-30
EA029305B1 true EA029305B1 (ru) 2018-03-30

Family

ID=45569726

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201490175A EA029305B1 (ru) 2011-08-23 2011-08-23 Составы дезоксихолевой кислоты и ее солей

Country Status (18)

Country Link
JP (1) JP5919597B2 (fr)
KR (5) KR101919269B1 (fr)
CN (3) CN108619089A (fr)
AU (3) AU2011375432B2 (fr)
BR (1) BR112014000547B1 (fr)
CA (1) CA2842177C (fr)
CR (1) CR20140053A (fr)
EA (1) EA029305B1 (fr)
IL (1) IL230547A (fr)
IN (1) IN2014CN02188A (fr)
MX (1) MX350390B (fr)
MY (1) MY184277A (fr)
NZ (1) NZ620040A (fr)
PH (1) PH12016501175A1 (fr)
SG (1) SG2014013205A (fr)
UA (1) UA113522C2 (fr)
WO (1) WO2013028177A1 (fr)
ZA (1) ZA201401027B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
JP2018532806A (ja) * 2015-11-04 2018-11-08 キセラ バイオファーマシューティカルズ インコーポレイテッド デオキシコール酸およびその塩による蓄積脂肪の処置方法
KR101841193B1 (ko) * 2016-09-22 2018-03-22 이경락 저장성 지방 분해 조성물 및 그의 제조 방법
US20180078621A1 (en) * 2016-09-22 2018-03-22 Kyoung Lack Lee Composition for hypotonic lipolysis and manufacturing method thereof
WO2019203511A1 (fr) * 2018-04-16 2019-10-24 주식회사 펜믹스 Composition pharmaceutique d'acide désoxycholique
KR102172439B1 (ko) * 2018-12-05 2020-10-30 송미희 지방 분해용 조성물 및 이를 포함하는 주사제 조성물
KR102064864B1 (ko) 2019-02-08 2020-01-10 (주)제테마 국소 주사용 조성물
KR102111346B1 (ko) * 2019-08-20 2020-05-22 아영창 침전으로부터 안정한 소듐디옥시콜레이트를 포함하는 수용액상 조성물
KR20220026068A (ko) 2020-08-25 2022-03-04 강명범 지방 분해용 주사제 조성물
CN116617160A (zh) * 2023-07-25 2023-08-22 山东则正医药技术有限公司 水性混悬液及制备方法、冻干粉及应用、脂肪消减注射剂

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417179B1 (en) * 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution
US20050261258A1 (en) * 2004-05-19 2005-11-24 Kolodney Michael S Methods and compositions for the non-surgical removal of fat
US20060127468A1 (en) * 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2754709B1 (fr) 1996-10-23 1999-03-05 Sanofi Sa Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition
AU758679B2 (en) * 1998-07-24 2003-03-27 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
DE10361067A1 (de) * 2003-12-22 2005-07-14 Aventis Pharma Deutschland Gmbh Medikamentöse Lipolyse von Fettansammlungen
US7754230B2 (en) 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
AU2006255097B2 (en) 2005-06-06 2012-02-09 Georgetown University Compositions and methods for lipo modeling
TW201011755A (en) 2008-09-10 2010-03-16 Skymedi Corp Flash memory system and its data recovery method
JP5420946B2 (ja) * 2009-03-23 2014-02-19 富士フイルム株式会社 胆汁酸を含むミノキシジル水性組成物
EP2645099A1 (fr) 2012-03-30 2013-10-02 Phares Pharmaceutical Research N.V. Compositions biopertinentes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417179B1 (en) * 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution
US20050261258A1 (en) * 2004-05-19 2005-11-24 Kolodney Michael S Methods and compositions for the non-surgical removal of fat
US20060127468A1 (en) * 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
"Kythera Biopharmaceuticals: Evaluation of safety and efficacy of ATX-101 in the reduction of submental fat", INTERNET CITATION, 21 March 2011 (2011-03-21), pages 1-6, XP002661530, Retrieved from the Internet:URL:http://clinicaltrials.gov/ct2/show/NCT01305577, [retrieved on 2011-10-18], the whole document *
ADAM M. ROTUNDA, STEVEN R. WEISS, LARRY S. RIVKIN: "Randomized double-blind clinical trial of subcutaneously injected deoxycholate versus a phosphatidylcholine-deoxycholate combination for the reduction of submental fat", DERMATOLOGIC SURGERY., WILEY-BLACKWELL PUBLISHING, INC., NEW YORK, US, vol. 35, no. 5, 1 May 2009 (2009-05-01), NEW YORK, US, pages 792 - 803, XP002661529, ISSN: 1076-0512, DOI: 10.1111/J.1524-4725.2009.01130.X *
FDA NEWS RELEASE: "FDA news release: FDA issues warning letters fro drugs promoted in fat elimination procedure", INTERNET CITATION, 7 April 2010 (2010-04-07), pages 1-2, XP002661531, Retrieved from the Internet: URL:http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm207453.htm, [retrieved on 2011-10-18], the whole document *

Also Published As

Publication number Publication date
EA201490175A1 (ru) 2014-06-30
KR101919269B1 (ko) 2018-11-15
AU2016202661B2 (en) 2018-02-22
PH12016501175B1 (en) 2017-12-11
CN103826608A (zh) 2014-05-28
JP2014524467A (ja) 2014-09-22
CN108619089A (zh) 2018-10-09
KR20170075016A (ko) 2017-06-30
JP5919597B2 (ja) 2016-05-18
AU2011375432A1 (en) 2014-02-06
UA113522C2 (xx) 2017-02-10
IN2014CN02188A (fr) 2015-05-29
CN108743522A (zh) 2018-11-06
BR112014000547A2 (pt) 2017-02-14
CA2842177C (fr) 2016-07-19
KR102034606B1 (ko) 2019-10-22
KR102073536B1 (ko) 2020-02-04
NZ620040A (en) 2016-06-24
KR20150000448A (ko) 2015-01-02
MY184277A (en) 2021-03-30
BR112014000547B1 (pt) 2021-11-09
AU2016202661A1 (en) 2016-05-19
KR20200013103A (ko) 2020-02-05
CA2842177A1 (fr) 2013-02-28
CR20140053A (es) 2014-06-12
MX2014001495A (es) 2014-04-25
MX350390B (es) 2017-09-06
IL230547A (en) 2017-02-28
KR20190119677A (ko) 2019-10-22
KR101751585B1 (ko) 2017-06-27
IL230547A0 (en) 2014-03-31
WO2013028177A1 (fr) 2013-02-28
AU2011375432B2 (en) 2016-02-04
AU2018202807B2 (en) 2020-01-16
PH12016501175A1 (en) 2017-12-11
SG2014013205A (en) 2014-05-29
AU2018202807A1 (en) 2018-05-10
KR20180123734A (ko) 2018-11-19
ZA201401027B (en) 2017-09-27

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