DZ3007A1 - Analogs of (1 R, CIS) -4- (6-amino-9H-purin-9-YL) -2-cyclopentene-1-methanol as antiviral agents. - Google Patents

Analogs of (1 R, CIS) -4- (6-amino-9H-purin-9-YL) -2-cyclopentene-1-methanol as antiviral agents.

Info

Publication number: DZ3007A1
Authority: DZ; Algeria
Prior art keywords: purin; cyclopentene; analogs; cis; methanol
Prior art date: 1999-02-12

Application number

DZ000019A

Other languages

French (fr)

Inventor

Susan Mary Daluge

Christopher Mcguigan

Original Assignee

Glaxo Group Ltd

Gbuniversity College Cardiff C

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-12

Filing date

2000-03-09

Publication date

2003-03-27

1999-02-12 Priority claimed from GBGB9903090.0A external-priority patent/GB9903090D0/en

2000-03-09 Application filed by Glaxo Group Ltd, Gbuniversity College Cardiff C filed Critical Glaxo Group Ltd

2003-03-27 Application granted granted Critical

2003-03-27 Publication of DZ3007A1 publication Critical patent/DZ3007A1/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses

DZ000019A 1999-02-12 2000-03-09 Analogs of (1 R, CIS) -4- (6-amino-9H-purin-9-YL) -2-cyclopentene-1-methanol as antiviral agents. DZ3007A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9903090.0A GB9903090D0 (en)	1999-02-12	1999-02-12	Therapeutic compounds
US17020599P	1999-12-10	1999-12-10

Publications (1)

Publication Number	Publication Date
DZ3007A1 true DZ3007A1 (en)	2003-03-27

Family

ID=26315118

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ000019A DZ3007A1 (en)	1999-02-12	2000-03-09	Analogs of (1 R, CIS) -4- (6-amino-9H-purin-9-YL) -2-cyclopentene-1-methanol as antiviral agents.

Country Status (24)

Country	Link
US (1)	US7115590B1 (en)
EP (1)	EP1150988B1 (en)
JP (1)	JP2002536452A (en)
KR (1)	KR20010102082A (en)
CN (1)	CN1346360A (en)
AR (1)	AR031975A1 (en)
AT (1)	ATE241633T1 (en)
AU (1)	AU772478B2 (en)
BR (1)	BR0008135A (en)
CA (1)	CA2362662A1 (en)
CZ (1)	CZ20012908A3 (en)
DE (1)	DE60002986T2 (en)
DK (1)	DK1150988T3 (en)
DZ (1)	DZ3007A1 (en)
ES (1)	ES2200820T3 (en)
HK (1)	HK1039337B (en)
HU (1)	HUP0105476A3 (en)
IL (1)	IL144647A0 (en)
NO (1)	NO20013910L (en)
NZ (1)	NZ513450A (en)
PL (1)	PL204458B1 (en)
PT (1)	PT1150988E (en)
TR (1)	TR200102313T2 (en)
WO (1)	WO2000047591A1 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001042255A1 (en) *	1999-12-10	2001-06-14	Glaxo Group Limited	(1R,CIS)-4-(4-AMINO-7H-PYRROLO'2,3-I(D) &excl; PYRIMIDINE-7-YL)-2-CYCLOPENTENE-1-METHANOL DERIVATIVES AS ANTIVIRAL
PE20010915A1 (en) *	1999-12-10	2001-09-29	Glaxo Group Ltd	(1S, CIS) -4- (2-AMINO-9H-PURIN-9-IL) -2-CYCLOPENTEN-1-METHANOL ANALOGS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS
EA200601591A1 (en)	2000-05-26	2007-02-27	Айденикс (Кайман) Лимитед	APPLICATION OF RIBONOUSALIC COMPOUNDS FOR TREATING FLAVIVIRUS AND PESTIVIRUS INFECTIONS
HRP20160074B1 (en) †	2000-07-21	2021-09-03	Gilead Sciences, Inc.	Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same
GB0129945D0 (en) *	2001-12-13	2002-02-06	Mrc Technology Ltd	Chemical compounds
GB0401088D0 (en)	2004-01-19	2004-02-18	Univ Cardiff	Phosphoramidate derivatives
EP2691409B1 (en)	2011-03-31	2018-02-21	Idenix Pharmaceuticals LLC.	Compounds and pharmaceutical compositions for the treatment of viral infections
EP2755983B1 (en)	2011-09-12	2017-03-15	Idenix Pharmaceuticals LLC.	Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
US8507460B2 (en)	2011-10-14	2013-08-13	Idenix Pharmaceuticals, Inc.	Substituted 3′,5′-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
US9296778B2 (en)	2012-05-22	2016-03-29	Idenix Pharmaceuticals, Inc.	3′,5′-cyclic phosphate prodrugs for HCV infection
AU2013266393B2 (en)	2012-05-22	2017-09-28	Idenix Pharmaceuticals Llc	D-amino acid compounds for liver disease
EP2852604B1 (en)	2012-05-22	2017-04-12	Idenix Pharmaceuticals LLC	3',5'-cyclic phosphoramidate prodrugs for hcv infection
EA027929B1 (en)	2012-05-25	2017-09-29	Янссен Сайенсиз Айрлэнд Юси	Uracyl spirooxetane nucleosides
WO2014052638A1 (en)	2012-09-27	2014-04-03	Idenix Pharmaceuticals, Inc.	Esters and malonates of sate prodrugs
ES2674980T3 (en)	2012-10-08	2018-07-05	Idenix Pharmaceuticals Llc	2'-chloro nucleoside analogs for HCV infection
US10723754B2 (en)	2012-10-22	2020-07-28	Idenix Pharmaceuticals Llc	2′,4′-bridged nucleosides for HCV infection
EP2935304A1 (en)	2012-12-19	2015-10-28	IDENIX Pharmaceuticals, Inc.	4'-fluoro nucleosides for the treatment of hcv
US9309275B2 (en)	2013-03-04	2016-04-12	Idenix Pharmaceuticals Llc	3′-deoxy nucleosides for the treatment of HCV
US9339541B2 (en)	2013-03-04	2016-05-17	Merck Sharp & Dohme Corp.	Thiophosphate nucleosides for the treatment of HCV
EP2970357A1 (en)	2013-03-13	2016-01-20	IDENIX Pharmaceuticals, Inc.	Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv
WO2014165542A1 (en)	2013-04-01	2014-10-09	Idenix Pharmaceuticals, Inc.	2',4'-fluoro nucleosides for the treatment of hcv
US10005779B2 (en)	2013-06-05	2018-06-26	Idenix Pharmaceuticals Llc	1′,4′-thio nucleosides for the treatment of HCV
EP3027636B1 (en)	2013-08-01	2022-01-05	Idenix Pharmaceuticals LLC	D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
WO2015161137A1 (en)	2014-04-16	2015-10-22	Idenix Pharmaceuticals, Inc.	3'-substituted methyl or alkynyl nucleosides for the treatment of hcv
LU100724B1 (en)	2016-07-14	2018-07-31	Atea Pharmaceuticals Inc	Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
EP3865136A1 (en)	2016-09-07	2021-08-18	ATEA Pharmaceuticals, Inc.	2'-substituted-n6-substituted purine nucleotides for corona virus treatment
WO2021173713A1 (en)	2020-02-27	2021-09-02	Atea Pharmaceuticals, Inc.	Highly active compounds against covid-19
US10874687B1 (en)	2020-02-27	2020-12-29	Atea Pharmaceuticals, Inc.	Highly active compounds against COVID-19

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5244896A (en) *	1990-09-14	1993-09-14	Marion Merrell Dow Inc.	Carbocyclic adenosine analogs useful as immunosuppressants
GB9505025D0 (en) *	1995-03-13	1995-05-03	Medical Res Council	Chemical compounds
US6887707B2 (en) *	1996-10-28	2005-05-03	University Of Washington	Induction of viral mutation by incorporation of miscoding ribonucleoside analogs into viral RNA
GB9821058D0 (en) *	1998-09-28	1998-11-18	Univ Cardiff	Chemical compound
WO2001042255A1 (en) *	1999-12-10	2001-06-14	Glaxo Group Limited	(1R,CIS)-4-(4-AMINO-7H-PYRROLO'2,3-I(D) &excl; PYRIMIDINE-7-YL)-2-CYCLOPENTENE-1-METHANOL DERIVATIVES AS ANTIVIRAL
US20030096833A1 (en) *	2001-08-31	2003-05-22	Jagtap Prakash G.	Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof

2000
- 2000-02-10 DK DK00905043T patent/DK1150988T3/en active
- 2000-02-10 CN CN00806002A patent/CN1346360A/en active Pending
- 2000-02-10 DE DE60002986T patent/DE60002986T2/en not_active Expired - Fee Related
- 2000-02-10 AT AT00905043T patent/ATE241633T1/en not_active IP Right Cessation
- 2000-02-10 AR ARP000100596A patent/AR031975A1/en not_active Application Discontinuation
- 2000-02-10 WO PCT/EP2000/001045 patent/WO2000047591A1/en not_active Application Discontinuation
- 2000-02-10 CA CA002362662A patent/CA2362662A1/en not_active Abandoned
- 2000-02-10 ES ES00905043T patent/ES2200820T3/en not_active Expired - Lifetime
- 2000-02-10 KR KR1020017010198A patent/KR20010102082A/en not_active Application Discontinuation
- 2000-02-10 BR BR0008135-3A patent/BR0008135A/en not_active IP Right Cessation
- 2000-02-10 IL IL14464700A patent/IL144647A0/en unknown
- 2000-02-10 JP JP2000598510A patent/JP2002536452A/en active Pending
- 2000-02-10 AU AU26713/00A patent/AU772478B2/en not_active Ceased
- 2000-02-10 PL PL350023A patent/PL204458B1/en not_active IP Right Cessation
- 2000-02-10 HU HU0105476A patent/HUP0105476A3/en unknown
- 2000-02-10 TR TR2001/02313T patent/TR200102313T2/en unknown
- 2000-02-10 PT PT00905043T patent/PT1150988E/en unknown
- 2000-02-10 CZ CZ20012908A patent/CZ20012908A3/en unknown
- 2000-02-10 EP EP00905043A patent/EP1150988B1/en not_active Expired - Lifetime
- 2000-02-10 US US09/913,226 patent/US7115590B1/en not_active Expired - Fee Related
- 2000-02-10 NZ NZ513450A patent/NZ513450A/en unknown
- 2000-03-09 DZ DZ000019A patent/DZ3007A1/en active
2001
- 2001-08-10 NO NO20013910A patent/NO20013910L/en not_active Application Discontinuation
2002
- 2002-02-05 HK HK02100897.2A patent/HK1039337B/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
US7115590B1 (en)	2006-10-03
AR031975A1 (en)	2003-10-22
ES2200820T3 (en)	2004-03-16
WO2000047591A1 (en)	2000-08-17
EP1150988B1 (en)	2003-05-28
NO20013910L (en)	2001-10-10
PL204458B1 (en)	2010-01-29
IL144647A0 (en)	2002-05-23
KR20010102082A (en)	2001-11-15
HK1039337A1 (en)	2002-04-19
HUP0105476A2 (en)	2002-06-29
NZ513450A (en)	2004-03-26
DK1150988T3 (en)	2003-09-29
ATE241633T1 (en)	2003-06-15
AU2671300A (en)	2000-08-29
PL350023A1 (en)	2002-10-21
NO20013910D0 (en)	2001-08-10
TR200102313T2 (en)	2002-03-21
CA2362662A1 (en)	2000-08-17
DE60002986D1 (en)	2003-07-03
CZ20012908A3 (en)	2002-10-16
BR0008135A (en)	2002-02-19
AU772478B2 (en)	2004-04-29
DE60002986T2 (en)	2004-05-19
CN1346360A (en)	2002-04-24
HUP0105476A3 (en)	2002-08-28
JP2002536452A (en)	2002-10-29
EP1150988A1 (en)	2001-11-07
PT1150988E (en)	2003-10-31
HK1039337B (en)	2003-11-21

Publication	Publication Date	Title
DZ3007A1 (en)	2003-03-27	Analogs of (1 R, CIS) -4- (6-amino-9H-purin-9-YL) -2-cyclopentene-1-methanol as antiviral agents.
PT1225874E (en)	2006-06-30	ANTIVIRAL COMPOSITIONS.
FR12C0041I2 (en)	2013-01-11	SOMATOSTATIN ANALOGS
WO1999064047A8 (en)	2001-03-08	Novel antiviral compounds
GC0000174A (en)	2006-03-29	Nucleoside analogues suitable for use as anti-viral agents
DE69920035D1 (en)	2004-10-14	HIGHLY CONCENTRATED AQUEOUS GLYPHOSATE COMPOSITIONS
AP2002002529A0 (en)	2002-06-30	2,4-Diaminopyrimidine compounds useful as immunosupressants
HK1041699A1 (en)	2002-07-19	Quinolinecarboxamides as antiviral agents
AP2003002932A0 (en)	2003-12-31	Thiophene derivatives as antiviral agents for flavviirus infection.
EE200200275A (en)	2003-10-15	2,4-Diaminopyrimidine compounds used as immunosuppressants
FR05C0032I2 (en)	2006-12-29	NUCLEOTIDE ANALOGS
MXPA03007595A (en)	2003-12-04	Ascorbic acid analogs for metalloradiopharmaceuticals.
GB0128526D0 (en)	2002-01-23	Nucleotide analogues
ZA976242B (en)	1998-03-18	Illudin analogs useful as antitumor agents.
MXPA03000107A (en)	2003-08-19	Pyrroloquinolones as antiviral agents.
EG23909A (en)	2007-12-30	Vatamin d, analogs
AU6807501A (en)	2002-01-02	1-aryl-4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents
AU7810098A (en)	1999-01-04	9-oxa prostaglandin analogs as ocular hypotensives
ATE377068T1 (en)	2007-11-15	SURFACTANT COMPOSITIONS CONTAINING IMPROVEMENT AGENTS
EP1568704A4 (en)	2009-12-02	Novel 2' ,5' -oligoadenylic acid analogues
HK1054037A1 (en)	2003-11-14	4-hydroxy-1,8-naphthyridine-3-carboxamides as antiviral agents
HK1051179A1 (en)	2003-07-25	Prostaglandin e analogues.
PL366978A1 (en)	2005-02-07	Hydroxyfattysulfonic acid analogs
GC0000195A (en)	2006-03-29	Benzoamido- and thiophenecarboxyamido-1,2,3,4-tetrahydroisoquinol-7-ine compunds as anticonvulsant agents
AU2068901A (en)	2001-06-18	Analogs of (1s, cis)-4-(2-amino-9h-purin-9-yl)-2-cyclopentene-1-methanol as antiviral