DZ2642A1 - Hydrohalogénures 1'-Ä4-Ä1-(fluorphényl)-1h-indole-3ylÜ-1-butylÜ-spiroÄisobenzufuran-1(3h),4'-pipéridineÜ. - Google Patents

Hydrohalogénures 1'-Ä4-Ä1-(fluorphényl)-1h-indole-3ylÜ-1-butylÜ-spiroÄisobenzufuran-1(3h),4'-pipéridineÜ.

Info

Publication number: DZ2642A1
Authority: DZ; Algeria
Prior art keywords: spiroäisobenzufuran; piperidineü; butylü; 3ylü; fluorphenyl
Prior art date: 1997-11-07

Application number

DZ980252A

Other languages

English (en)

Inventor

Niels Mark

Heidi Lopez De Diego

Ole Nielsen

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-07

Filing date

1998-11-04

Publication date

2004-12-28

1998-11-04 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2004-12-28 Application granted granted Critical

2004-12-28 Publication of DZ2642A1 publication Critical patent/DZ2642A1/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

DZ980252A 1997-11-07 1998-11-04 Hydrohalogénures 1'-Ä4-Ä1-(fluorphényl)-1h-indole-3ylÜ-1-butylÜ-spiroÄisobenzufuran-1(3h),4'-pipéridineÜ. DZ2642A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK126797		1997-11-07

Publications (1)

Publication Number	Publication Date
DZ2642A1 true DZ2642A1 (fr)	2004-12-28

Family

ID=8102935

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ980252A DZ2642A1 (fr)	1997-11-07	1998-11-04	Hydrohalogénures 1'-Ä4-Ä1-(fluorphényl)-1h-indole-3ylÜ-1-butylÜ-spiroÄisobenzufuran-1(3h),4'-pipéridineÜ.

Country Status (39)

Country	Link
US (2)	US6844352B2 (fr)
EP (1)	EP1044202B1 (fr)
JP (1)	JP3605358B2 (fr)
KR (1)	KR100399274B1 (fr)
CN (1)	CN1105115C (fr)
AR (1)	AR023010A1 (fr)
AT (1)	ATE288918T1 (fr)
AU (1)	AU749094B2 (fr)
BG (1)	BG64906B1 (fr)
BR (1)	BR9813949A (fr)
CA (1)	CA2308745C (fr)
CZ (1)	CZ288666B6 (fr)
DE (1)	DE69828999T2 (fr)
DZ (1)	DZ2642A1 (fr)
EA (1)	EA002092B1 (fr)
EG (1)	EG23791A (fr)
ES (1)	ES2234162T3 (fr)
HK (1)	HK1034075A1 (fr)
HR (1)	HRP20000261B1 (fr)
HU (1)	HUP0100991A3 (fr)
ID (1)	ID25776A (fr)
IL (1)	IL135723A (fr)
IS (1)	IS2342B (fr)
JO (1)	JO2052B1 (fr)
MA (1)	MA25585A1 (fr)
NO (1)	NO325920B1 (fr)
NZ (1)	NZ504065A (fr)
PE (1)	PE130299A1 (fr)
PL (1)	PL190538B1 (fr)
PT (1)	PT1044202E (fr)
RS (1)	RS49777B (fr)
SK (1)	SK285245B6 (fr)
TN (1)	TNSN98201A1 (fr)
TR (1)	TR200001267T2 (fr)
TW (1)	TW483894B (fr)
UA (1)	UA64769C2 (fr)
UY (1)	UY25236A1 (fr)
WO (1)	WO1999024436A1 (fr)
ZA (1)	ZA9810116B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2001279607A1 (en) *	2000-08-15	2002-02-25	H. Lundbeck, A/S	Pharmaceutical composition containing 1'-(4-(1-(4-fluorophenyl)-1h-indole-3-yl) -1-butyl)-spiro(isobenzofuran-1(3h),4'-piperidine)
AU2003263155A1 (en) *	2002-09-20	2004-04-08	H. Lundbeck A/S	Method for manufacture of dihydroisobenzofuran derivatives
US20050032827A1 (en) *	2003-06-12	2005-02-10	Donna Oksenberg	Sigma ligands for neuronal regeneration and functional recovery
US20090306341A1 (en) *	2005-07-29	2009-12-10	Joachim Emmert	LC/MS Blends Containing Ionizing Additives
AU2006304787A1 (en)	2005-10-21	2007-04-26	Braincells, Inc.	Modulation of neurogenesis by PDE inhibition
CA2625210A1 (fr)	2005-10-31	2007-05-10	Braincells, Inc.	Modulation de la neurogenese dont la mediation est assuree par recepteur gaba
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
AU2007223036A1 (en) *	2006-03-08	2007-09-13	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
EP2026813A2 (fr) *	2006-05-09	2009-02-25	Braincells, Inc.	Neurogenèse induite par le récepteur 5ht
US20100009983A1 (en) *	2006-05-09	2010-01-14	Braincells, Inc.	5 ht receptor mediated neurogenesis
EP2377531A2 (fr)	2006-05-09	2011-10-19	Braincells, Inc.	Neurogénèse par modulation de l'angiotensine
US7998971B2 (en) *	2006-09-08	2011-08-16	Braincells Inc.	Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
EP2066355A2 (fr) *	2006-09-19	2009-06-10	Braincells, Inc.	Combinaison comprenant un agent ppar et un deuxième agent neurogène pour le traitement d'une maladie du système nerveux central, pour augmenter la différentiation neuronale et pour augmenter la neurogenèse
US20100216805A1 (en)	2009-02-25	2010-08-26	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5109002A (en) *	1989-09-08	1992-04-28	Du Pont Merck Pharmaceutical Company	Antipsychotic 1-cycloalkylpiperidines
NZ243065A (en) *	1991-06-13	1995-07-26	Lundbeck & Co As H	Piperidine derivatives and pharmaceutical compositions

1998
- 1998-06-11 UA UA2000052828A patent/UA64769C2/uk unknown
- 1998-10-20 TW TW087117299A patent/TW483894B/zh not_active IP Right Cessation
- 1998-10-27 MA MA25316A patent/MA25585A1/fr unknown
- 1998-11-03 EG EG136298A patent/EG23791A/xx active
- 1998-11-04 DZ DZ980252A patent/DZ2642A1/fr active
- 1998-11-04 TN TNTNSN98201A patent/TNSN98201A1/fr unknown
- 1998-11-05 ZA ZA9810116A patent/ZA9810116B/xx unknown
- 1998-11-05 JO JO19982052A patent/JO2052B1/en active
- 1998-11-05 AR ARP980105596A patent/AR023010A1/es active IP Right Grant
- 1998-11-05 PE PE1998001067A patent/PE130299A1/es not_active Application Discontinuation
- 1998-11-06 ES ES98952580T patent/ES2234162T3/es not_active Expired - Lifetime
- 1998-11-06 BR BR9813949-5A patent/BR9813949A/pt not_active Application Discontinuation
- 1998-11-06 CZ CZ20001663A patent/CZ288666B6/cs not_active IP Right Cessation
- 1998-11-06 UY UY25236A patent/UY25236A1/es not_active IP Right Cessation
- 1998-11-06 AU AU10226/99A patent/AU749094B2/en not_active Ceased
- 1998-11-06 AT AT98952580T patent/ATE288918T1/de not_active IP Right Cessation
- 1998-11-06 IL IL13572398A patent/IL135723A/xx not_active IP Right Cessation
- 1998-11-06 TR TR2000/01267T patent/TR200001267T2/xx unknown
- 1998-11-06 NZ NZ504065A patent/NZ504065A/en unknown
- 1998-11-06 JP JP2000520446A patent/JP3605358B2/ja not_active Expired - Fee Related
- 1998-11-06 CA CA002308745A patent/CA2308745C/fr not_active Expired - Fee Related
- 1998-11-06 EP EP98952580A patent/EP1044202B1/fr not_active Expired - Lifetime
- 1998-11-06 PL PL98340220A patent/PL190538B1/pl not_active IP Right Cessation
- 1998-11-06 KR KR10-2000-7004858A patent/KR100399274B1/ko not_active IP Right Cessation
- 1998-11-06 CN CN98810910A patent/CN1105115C/zh not_active Expired - Fee Related
- 1998-11-06 ID IDW20000997D patent/ID25776A/id unknown
- 1998-11-06 SK SK646-2000A patent/SK285245B6/sk not_active IP Right Cessation
- 1998-11-06 EA EA200000502A patent/EA002092B1/ru not_active IP Right Cessation
- 1998-11-06 DE DE69828999T patent/DE69828999T2/de not_active Expired - Fee Related
- 1998-11-06 HU HU0100991A patent/HUP0100991A3/hu unknown
- 1998-11-06 RS YUP-235/00A patent/RS49777B/sr unknown
- 1998-11-06 PT PT98952580T patent/PT1044202E/pt unknown
- 1998-11-06 WO PCT/DK1998/000480 patent/WO1999024436A1/fr active IP Right Grant
2000
- 2000-04-18 IS IS5460A patent/IS2342B/is unknown
- 2000-04-27 NO NO20002188A patent/NO325920B1/no not_active IP Right Cessation
- 2000-05-04 HR HR20000261A patent/HRP20000261B1/xx not_active IP Right Cessation
- 2000-05-29 BG BG104485A patent/BG64906B1/bg unknown
2001
- 2001-06-28 HK HK01104490A patent/HK1034075A1/xx not_active IP Right Cessation
2002
- 2002-10-15 US US10/272,403 patent/US6844352B2/en not_active Expired - Fee Related
2004
- 2004-12-13 US US11/012,084 patent/US20050171135A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EA200000502A1 (ru)	2000-10-30
JO2052B1 (en)	1999-05-15
JP3605358B2 (ja)	2004-12-22
CN1278823A (zh)	2001-01-03
WO1999024436A1 (fr)	1999-05-20
HRP20000261A2 (en)	2001-04-30
CZ20001663A3 (cs)	2000-10-11
CZ288666B6 (cs)	2001-08-15
DE69828999T2 (de)	2005-07-21
CN1105115C (zh)	2003-04-09
DE69828999D1 (de)	2005-03-17
HUP0100991A3 (en)	2003-03-28
IL135723A0 (en)	2001-05-20
RS49777B (sr)	2008-06-05
TR200001267T2 (tr)	2000-09-21
US20030055074A1 (en)	2003-03-20
TNSN98201A1 (fr)	2005-03-15
NO20002188D0 (no)	2000-04-27
CA2308745C (fr)	2004-01-20
EA002092B1 (ru)	2001-12-24
NO325920B1 (no)	2008-08-18
ATE288918T1 (de)	2005-02-15
SK6462000A3 (en)	2000-10-09
ID25776A (id)	2000-11-02
US6844352B2 (en)	2005-01-18
YU23500A (sh)	2003-12-31
TW483894B (en)	2002-04-21
SK285245B6 (sk)	2006-09-07
US20050171135A1 (en)	2005-08-04
BG104485A (en)	2001-01-31
KR20010031791A (ko)	2001-04-16
BR9813949A (pt)	2000-09-26
NO20002188L (no)	2000-06-14
ZA9810116B (en)	1999-05-07
AR023010A1 (es)	2002-09-04
AU1022699A (en)	1999-05-31
HUP0100991A2 (hu)	2001-09-28
ES2234162T3 (es)	2005-06-16
KR100399274B1 (ko)	2003-09-26
CA2308745A1 (fr)	1999-05-20
IS5460A (is)	2000-04-18
PT1044202E (pt)	2005-04-29
HK1034075A1 (en)	2001-10-12
IS2342B (is)	2008-02-15
EP1044202A1 (fr)	2000-10-18
BG64906B1 (bg)	2006-08-31
PL340220A1 (en)	2001-01-15
NZ504065A (en)	2002-05-31
PE130299A1 (es)	1999-12-16
IL135723A (en)	2005-11-20
MA25585A1 (fr)	2002-12-31
AU749094B2 (en)	2002-06-20
UA64769C2 (uk)	2004-03-15
JP2001522852A (ja)	2001-11-20
UY25236A1 (es)	2000-12-29
HRP20000261B1 (en)	2009-04-30
EG23791A (en)	2007-08-13
EP1044202B1 (fr)	2005-02-09
PL190538B1 (pl)	2005-12-30

Publication	Publication Date	Title
SV1996000005A (es)	1997-03-11	Quinazolinonas bisustituidas en 2,8
IS4963A (is)	1999-01-29	Setnar 6,5-heteró-bísýklískar afleiður
TR199800444A3 (tr)	1998-10-21	Hipolipidemik 1,4-benzotiazepin-1,1-diyoksitler.
NO2006016I1 (no)	2006-11-27	7,8,9,10-tetrahydro-6H-6,10-metanoazepinoÄ4,5-gÜkinoksalintartrat
PT993456E (pt)	2005-01-31	4,5-diaril-imidazoles 2-substituidos
NL300150I1 (nl)	2004-08-02	4"-Gesubstitueerde 9-deoxo-9A-AZA-9A-homoërythromycine-A-derivaten.
PT901487E (pt)	2003-08-29	4(3h)-quinazolinonas 2,3,6-trissubstituidas
TR28098A (tr)	1996-01-08	1,2,4-okzadiazol türevleri.
TR27961A (tr)	1995-11-06	Sübstitüe edilmis 1,2,3,4 -tetrahidro-5-nitro-pirimidinler.
DK1015467T3 (da)	2004-05-03	6,9-brobundne erythromycinderivater
DZ2642A1 (fr)	2004-12-28	Hydrohalogénures 1'-Ä4-Ä1-(fluorphényl)-1h-indole-3ylÜ-1-butylÜ-spiroÄisobenzufuran-1(3h),4'-pipéridineÜ.
ID21413A (id)	1999-06-10	Turunan-turunan 1,3,8,-triaza-spiro (4,5) dekan-4-on
DE69814441D1 (de)	2003-06-12	6,11-verbrückte erythromycinderivate
TR199800988A3 (tr)	1998-12-21	5' Deoksi-Sitidin türevleri.
CY2425B1 (en)	2004-11-12	2,4-Diaminopyrimidine derivatives.
ZA982327B (en)	1999-09-20	Substituted 2-benz(O)ylpyridines.
ID26909A (id)	2001-02-15	Turunan-turunan 1,3,4-oksadiazolon
DE69906149T2 (de)	2003-12-18	4,5-azolo-oxindole
TR199501562A2 (tr)	1996-07-21	Tiyenopiridon'lar.
ZA986160B (en)	2000-01-10	2,4,4-trisubstituted-1,3-dioxolone antifungals.
ID24047A (id)	2000-07-06	Turunan 5-tersubstitusi-3-oksaziazolil 1,6-naftiridin-2 1h-on
ID26368A (id)	2000-12-14	Turunan-turunan 2 deoksi higromisin
TR199700219A3 (tr)	1997-10-21	1,25-Dihidroksi-16, 22, 23-Trisdihidro-kolkalsiferol türevleri.
ZA984592B (en)	1999-11-29	Herbicidal 3,5-difluoropyridines.
TR199600579A2 (tr)	1997-01-21	N-N-Dietil-8,8-Dipropil-2-Azaspiro (4.5) Dekan-2-propanamid dimaleat.