DOP2007000030A - NEW PHARMACEUTICAL PRODUCTS - Google Patents

NEW PHARMACEUTICAL PRODUCTS

Info

Publication number
DOP2007000030A
DOP2007000030A DO2007000030A DO2007000030A DOP2007000030A DO P2007000030 A DOP2007000030 A DO P2007000030A DO 2007000030 A DO2007000030 A DO 2007000030A DO 2007000030 A DO2007000030 A DO 2007000030A DO P2007000030 A DOP2007000030 A DO P2007000030A
Authority
DO
Dominican Republic
Prior art keywords
pharmaceutical products
inhibitors
new pharmaceutical
agonism
tlr
Prior art date
Application number
DO2007000030A
Other languages
Spanish (es)
Inventor
Peter Jones
David Cameron Pryde
Thien Duc Tran
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of DOP2007000030A publication Critical patent/DOP2007000030A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a modificadores de la respuesta inmune de fórmula (I), que actúan de forma selectiva por agonismo de receptores similares a Toll (TLR), a usos de los mismos, a procedimientos para la preparación de los mismos, a intermedios usados en la preparación de los mismos y a composiciones que contienen dichos inhibidores. Estos inhibidores tienen utilidad en una diversidad de áreas terapeúticas incluyendo el tratamiento de enfermedades infecciosas tales como Hepatitis (por ejemplo, HCV, HBV), infecciones víricas genéticamente relacionadas y cáncer.The present invention relates to immune response modifiers of formula (I), which act selectively by agonism of Toll-like receptors (TLR), to uses thereof, to methods for preparing them, to intermediates. used in the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including the treatment of infectious diseases such as hepatitis (eg, HCV, HBV), genetically related viral infections and cancer.

DO2007000030A 2006-02-17 2007-02-13 NEW PHARMACEUTICAL PRODUCTS DOP2007000030A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77458006P 2006-02-17 2006-02-17

Publications (1)

Publication Number Publication Date
DOP2007000030A true DOP2007000030A (en) 2007-09-15

Family

ID=40463757

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2007000030A DOP2007000030A (en) 2006-02-17 2007-02-13 NEW PHARMACEUTICAL PRODUCTS

Country Status (3)

Country Link
CN (1) CN101384593A (en)
DO (1) DOP2007000030A (en)
ZA (1) ZA200806811B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015004534A2 (en) 2013-06-21 2015-01-15 Zenith Epigenetics Corp. Novel substituted bicyclic compounds as bromodomain inhibitors
WO2015002754A2 (en) 2013-06-21 2015-01-08 Zenith Epigenetics Corp. Novel bicyclic bromodomain inhibitors
US9855271B2 (en) 2013-07-31 2018-01-02 Zenith Epigenetics Ltd. Quinazolinones as bromodomain inhibitors
EP3227281A4 (en) 2014-12-01 2018-05-30 Zenith Epigenetics Ltd. Substituted pyridinones as bromodomain inhibitors
CA2966303A1 (en) 2014-12-01 2016-06-09 Zenith Epigenetics Ltd. Substituted pyridines as bromodomain inhibitors
JP2017537946A (en) 2014-12-11 2017-12-21 ゼニス・エピジェネティクス・リミテッドＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｌｔｄ． Substituted heterocycles as bromodomain inhibitors
CA2966450A1 (en) 2014-12-17 2016-06-23 Olesya KHARENKO Inhibitors of bromodomains
EP3636646A4 (en) * 2017-05-18 2020-12-09 Jiangsu Hengrui Medicine Co., Ltd. Heteroaryl-pyrazole derivative, and preparation method therefor and medical application thereof
CN107188891A (en) * 2017-06-29 2017-09-22 天津药明康德新药开发有限公司 A kind of synthetic method of 5 (tert-butyl carbonyl) 1 methylimidazoles and the carboxylic acid of pyridine 7
CN112654622B (en) * 2018-11-07 2023-10-03 四川科伦博泰生物医药股份有限公司 Ring-fused compound, preparation method and application thereof
JP2023550793A (en) * 2020-11-26 2023-12-05 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 Fused tricyclic compounds, their preparation methods and their pharmaceutical applications
CN113750095B (en) * 2021-03-10 2023-07-04 中国医学科学院医药生物技术研究所 Application of compound containing cyclopropyl skeleton in preparation of medicines for treating and/or preventing coronavirus infection

Also Published As

Publication number Publication date
CN101384593A (en) 2009-03-11
ZA200806811B (en) 2010-01-27

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