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Application filed by Pfizer Prod IncfiledCriticalPfizer Prod Inc
Priority to DO2002000419ApriorityCriticalpatent/DOP2002000419A/en
Publication of DOP2002000419ApublicationCriticalpatent/DOP2002000419A/en
Inhibidores de CETP que tienen mejor solubilidad y biodisponibilidad en un vehículo lipófilo que comprende un aceite digerible, un disolvente lipófilo o un tensioactivo. Tales composiciones preferidas son autoemulsionantes o automicroemulsionantes y comprenden 1. un inhibidor de CETP; 2. un codisolvente; 3. un tensioactivo que tiene un HLB de 1 a 8; 4. un tensioactivo que tiene un HLB de 8 a 20; y 5. opcionalmente, un aceite digerible.CETP inhibitors that have better solubility and bioavailability in a lipophilic vehicle comprising a digestible oil, a lipophilic solvent or a surfactant. Such preferred compositions are self-emulsifying or self-emulsifying and comprise 1. a CETP inhibitor; 2. a co-solvent; 3. a surfactant having an HLB of 1 to 8; 4. a surfactant having an HLB of 8 to 20; and 5. optionally, a digestible oil.
DO2002000419A2002-06-182002-06-18
SELF-EMULSIONING FORMULATIONS OF INHIBITORS OF THE ESTER CHOLESTERILE TRANSFER PROTECTION.
DOP2002000419A
(en)
PIRAZOL-CARBOXANILIDS, PROCEDURE FOR OBTAINING, COMPOSITIONS, USE OF SUCH COMPOUNDS AND PROCEDURE FOR THE FIGHT AGAINST INDESEABLE MICROORGANISMS, AND PROCEDURE FOR OBTAINING SUCH COMPOSITIONS.