DK89091A - Fremgangsmaade til fremstilling af vitamin-d-forbindelser - Google Patents

Fremgangsmaade til fremstilling af vitamin-d-forbindelser Download PDF

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Publication number
DK89091A
DK89091A DK089091A DK89091A DK89091A DK 89091 A DK89091 A DK 89091A DK 089091 A DK089091 A DK 089091A DK 89091 A DK89091 A DK 89091A DK 89091 A DK89091 A DK 89091A
Authority
DK
Denmark
Prior art keywords
vitamin
compounds
procedure
preparation
Prior art date
Application number
DK089091A
Other languages
English (en)
Other versions
DK89091D0 (da
Inventor
Hector F Deluca
Heinrich K Schnoes
Kato L Perlman
Andrzej Kutner
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK89091D0 publication Critical patent/DK89091D0/da
Publication of DK89091A publication Critical patent/DK89091A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK089091A 1988-04-29 1991-05-13 Fremgangsmaade til fremstilling af vitamin-d-forbindelser DK89091A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/187,680 US4927815A (en) 1988-04-29 1988-04-29 Compounds effective in inducing cell differentiation and process for preparing same

Publications (2)

Publication Number Publication Date
DK89091D0 DK89091D0 (da) 1991-05-13
DK89091A true DK89091A (da) 1991-05-13

Family

ID=22690003

Family Applications (2)

Application Number Title Priority Date Filing Date
DK666589A DK666589A (da) 1988-04-29 1989-12-22 D-vitamin homologer
DK089091A DK89091A (da) 1988-04-29 1991-05-13 Fremgangsmaade til fremstilling af vitamin-d-forbindelser

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK666589A DK666589A (da) 1988-04-29 1989-12-22 D-vitamin homologer

Country Status (15)

Country Link
US (2) US4927815A (da)
EP (1) EP0375757A1 (da)
JP (2) JPH0725730B2 (da)
KR (1) KR930011151B1 (da)
AU (1) AU630096B2 (da)
CA (1) CA1340615C (da)
DK (2) DK666589A (da)
FR (1) FR2630740A1 (da)
GB (1) GB2217715A (da)
HU (1) HU206083B (da)
IE (1) IE67868B1 (da)
IL (1) IL90066A (da)
IN (1) IN170659B (da)
NL (1) NL8920414A (da)
WO (1) WO1989010353A1 (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250523A (en) * 1988-04-29 1993-10-05 Wisconsin Alumni Research Foundation Side chain unsaturated 1α-hydroxyvitanim D homologs
CA1339383C (en) * 1989-03-09 1997-08-26 Hector Floyd Deluca Method for preparing intermediates for the synthesis of steroid side chains in optically active form
DE3933034A1 (de) * 1989-10-02 1991-04-11 Schering Ag 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
US5276061A (en) * 1990-08-24 1994-01-04 Wisconsin Alumni Research Foundation Cosmetic compositions containing 1α-hydroxyvitamin D homologs
US5459136A (en) * 1990-08-24 1995-10-17 Wisconsin Alumni Research Foundation Methods using vitamin D compounds for improvement of skin conditions
US5756783A (en) * 1990-09-21 1998-05-26 Bone Care International, Inc. 1α-Hydroxy-24-EPI-vitamin D4
DE4221961A1 (de) * 1992-06-30 1994-01-05 Schering Ag 22-En-25-oxa-Derivate in der Vitamin D-Reihe, Verfahren zu ihrer Herstellung, diese Derivate enthaltenen pharmazeutische Präparate sowie deren Verwendung als Arzneimittel
US5380720A (en) * 1993-05-11 1995-01-10 Wisconsin Alumni Research Foundation Iodo vitamin D3 compounds and method for preparing same
PE28297A1 (es) * 1995-01-26 1997-08-20 Hoffmann La Roche Empleo dermatologico de derivados de vitamina d
US5744128A (en) * 1995-05-03 1998-04-28 Holick; Michael F. Use of emu oil for stimulating skin and hair growth
CA2175881A1 (en) * 1995-05-09 1996-11-10 Andrzej Kutner Vitamin d compounds and methods of preparing these compounds
AUPO727097A0 (en) * 1997-06-10 1997-07-03 Unisearch Limited Method of treatment of hepatoma and pharmaceutical compositions for use therein
ES2368824T3 (es) 1998-03-27 2011-11-22 Oregon Health & Science University Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos.
DK1180035T3 (da) * 1999-04-01 2007-03-05 Univ Johns Hopkins Ikke kalcemiske, antiproliferative, transkriptionsmæssigt aktive svovlholdige analoger af 1-alpha, 25-dihydroxy-vitamin D3
AU2058701A (en) 1999-12-02 2001-06-12 F. Hoffmann-La Roche Ag Esters of vitamin D3 and uses thereof
US7166585B2 (en) * 2001-08-22 2007-01-23 Cytochroma Inc. 24-Sulfur-substituted analogs of 1α,25-dihydroxy vitamin D3
CA2481909C (en) * 2002-04-11 2013-07-02 Instytut Farmaceutyczny Preparation of 24-alkyl analogs of cholecalciferol
AU2005216651A1 (en) * 2004-03-01 2005-09-09 Bioxell Spa Treatment of interstitial cystitis with vitamin D compounds
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
AU2008242711A1 (en) * 2007-04-18 2008-10-30 Johns Hopkins University Low calcemic, highly antiproliferative, analogs of calcitriol
AU2010208323B2 (en) * 2009-01-27 2016-03-10 Berg Llc Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy
EP2464357B1 (en) 2009-08-14 2019-05-22 Berg LLC Vitamin d3 and analogs thereof for treating alopecia
US8754067B2 (en) 2010-11-12 2014-06-17 Wisconsin Alumni Research Foundation 22-haloacetoxy-homopregnacalciferol analogs and their uses
KR20160013201A (ko) 2013-05-29 2016-02-03 버그 엘엘씨 비타민 d를 이용한 화학요법 유발 탈모증의 예방 또는 완화
CN110981765A (zh) * 2019-11-07 2020-04-10 肇庆巨元生化有限公司 一种25-羟基维生素d3中间体的制备方法
CN112920096A (zh) * 2019-12-05 2021-06-08 四川大学 一种制备2-甲基-4-(苯磺酰基)-2-丁醇的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986002078A1 (en) * 1984-10-04 1986-04-10 Wisconsin Alumni Research Foundation Vitamin d derivatives and methods for preparing same
US4717721A (en) * 1985-05-30 1988-01-05 Howard W. Bremer Sidechain homo-vitamin D compounds with preferential anti-cancer activity
DE3687377T2 (de) * 1985-01-17 1993-04-29 Wisconsin Alumni Res Found Vitamin-d-abkoemmlinge und deren herstellungsverfahren.
IL77668A (en) * 1986-01-21 1989-03-31 Teva Pharma Production of cholecalciferol derivatives and novel intermediates used therefor
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
KR0144358B1 (ko) * 1988-04-21 1998-07-15 피. 라이달 크리스텐슨 비타민 d 동족체
EP0374219A1 (en) * 1988-04-29 1990-06-27 Wisconsin Alumni Research Foundation SIDE CHAIN UNSATURATED 1$g(a)-HYDROXYVITAMIN D HOMOLOGS

Also Published As

Publication number Publication date
WO1989010353A1 (en) 1989-11-02
EP0375757A1 (en) 1990-07-04
JPH02504154A (ja) 1990-11-29
IL90066A0 (en) 1989-12-15
DK666589A (da) 1990-02-28
US4927815A (en) 1990-05-22
NL8920414A (nl) 1990-04-02
GB2217715A (en) 1989-11-01
HU206083B (en) 1992-08-28
IN170659B (da) 1992-05-02
CA1340615C (en) 1999-06-29
KR930011151B1 (ko) 1993-11-24
IE891406L (en) 1989-10-29
DK89091D0 (da) 1991-05-13
HU892989D0 (en) 1990-06-28
JPH0725730B2 (ja) 1995-03-22
JP2505713B2 (ja) 1996-06-12
JPH0748343A (ja) 1995-02-21
US5061699A (en) 1991-10-29
KR900700449A (ko) 1990-08-13
FR2630740A1 (fr) 1989-11-03
AU630096B2 (en) 1992-10-22
IL90066A (en) 1995-12-08
IE67868B1 (en) 1996-05-01
GB8909570D0 (en) 1989-06-14
HUT52475A (en) 1990-07-28
DK666589D0 (da) 1989-12-22
AU3573089A (en) 1989-11-24

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