DK83886A - Pyrazolanaloge af mevalonolacton og derivater deraf, fremgangsmaader til fremstilling deraf og deres anvendelse - Google Patents
Pyrazolanaloge af mevalonolacton og derivater deraf, fremgangsmaader til fremstilling deraf og deres anvendelse Download PDFInfo
- Publication number
- DK83886A DK83886A DK83886A DK83886A DK83886A DK 83886 A DK83886 A DK 83886A DK 83886 A DK83886 A DK 83886A DK 83886 A DK83886 A DK 83886A DK 83886 A DK83886 A DK 83886A
- Authority
- DK
- Denmark
- Prior art keywords
- denotes
- alkyl
- symbols
- phenoxy
- trifluoromethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
- G06F13/38—Information transfer, e.g. on bus
- G06F13/382—Information transfer, e.g. on bus using universal interface adapter
- G06F13/387—Information transfer, e.g. on bus using universal interface adapter for adaptation of different data processing systems to different peripheral devices, e.g. protocol converters for incompatible systems, open system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
- G06F13/38—Information transfer, e.g. on bus
- G06F13/40—Bus structure
- G06F13/4004—Coupling between buses
- G06F13/4009—Coupling between buses with data restructuring
- G06F13/4018—Coupling between buses with data restructuring with data-width conversion
Landscapes
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Theoretical Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Computer Hardware Design (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62339384A | 1984-06-22 | 1984-06-22 | |
| US62339384 | 1984-06-22 | ||
| EP8500293 | 1985-06-18 | ||
| PCT/EP1985/000293 WO1986000307A2 (en) | 1984-06-22 | 1985-06-18 | Pyrazole analogs of mevalonolactone and derivatives thereof, processes for their production and their use |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK83886A true DK83886A (da) | 1986-02-21 |
| DK83886D0 DK83886D0 (da) | 1986-02-21 |
| DK157543B DK157543B (da) | 1990-01-22 |
| DK157543C DK157543C (da) | 1990-06-11 |
Family
ID=24497918
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK083886A DK157543C (da) | 1984-06-22 | 1986-02-21 | Pyrazolanaloge af mevalonolacton og derivater deraf samt deres anvendelse |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0200736B1 (da) |
| JP (1) | JPS61502467A (da) |
| KR (1) | KR890001651B1 (da) |
| AT (1) | ATE62906T1 (da) |
| AU (1) | AU573368B2 (da) |
| CA (1) | CA1249283A (da) |
| DE (1) | DE3582674D1 (da) |
| DK (1) | DK157543C (da) |
| ES (1) | ES8703842A1 (da) |
| FI (1) | FI860755A (da) |
| GR (1) | GR851510B (da) |
| HU (1) | HU198711B (da) |
| IL (1) | IL75583A (da) |
| MY (1) | MY101903A (da) |
| NZ (1) | NZ212501A (da) |
| PL (1) | PL151016B1 (da) |
| PT (1) | PT80674B (da) |
| WO (1) | WO1986000307A2 (da) |
| ZA (1) | ZA854719B (da) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4668794A (en) * | 1985-05-22 | 1987-05-26 | Sandoz Pharm. Corp. | Intermediate imidazole acrolein analogs |
| HUT48208A (en) * | 1985-10-25 | 1989-05-29 | Sandoz Ag | Process for producing heterocyclic analogues of mevalolactone derivatives and pharmaceutical compositions comprising such compounds |
| EP0244364A3 (en) * | 1986-04-30 | 1992-04-01 | Sandoz Ag | Preparation of olefinic compounds |
| US4808621A (en) * | 1986-07-07 | 1989-02-28 | Warner-Lambert Company | Trans-6-[2-(N-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl]- or ethenyl]tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
| PT85662B (pt) * | 1986-09-10 | 1990-06-29 | Sandoz Sa | Processo para a preparacao de derivados de aza-indol e de indolizina e de composicoes farmaceuticas que os contem |
| US4751235A (en) * | 1986-12-23 | 1988-06-14 | Sandoz Pharm. Corp. | Anti-atherosclerotic indolizine derivatives |
| US4735958A (en) * | 1986-12-22 | 1988-04-05 | Warner-Lambert Company | Trans-6-[2-[2-(substituted-phenyl)-3- (or 4-) heteroaryl-5-substituted-1H-pyrrol-1-yl]-ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one inhibitors of cholesterol biosynthesis |
| US4898949A (en) * | 1987-02-25 | 1990-02-06 | Bristol-Myers Company | Intermediates for the preparation of antihypercholesterolemic tetrazole compounds |
| US4897490A (en) * | 1987-02-25 | 1990-01-30 | Bristol-Meyers Company | Antihypercholesterolemic tetrazole compounds |
| AT401518B (de) * | 1987-02-25 | 1996-09-25 | Bristol Myers Squibb Co | Neue tetrazol-verbindungen und verfahren zu ihrer herstellung |
| JP2569746B2 (ja) * | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
| CA1336714C (en) * | 1987-08-20 | 1995-08-15 | Yoshihiro Fujikawa | Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis |
| US4906624A (en) * | 1987-09-08 | 1990-03-06 | Warner-Lambert Company | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
| US4997837A (en) * | 1987-09-08 | 1991-03-05 | Warner-Lambert Company | 6-(((substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
| DE3800785A1 (de) * | 1988-01-09 | 1989-07-20 | Hoechst Ag | Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte |
| US4822799A (en) * | 1988-01-27 | 1989-04-18 | Sandoz Pharm. Corp. | Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals |
| NO890522L (no) * | 1988-02-25 | 1989-08-28 | Bayer Ag | Substituerte imidazolinoner og imidazolinthioner. |
| US5024999A (en) * | 1988-04-26 | 1991-06-18 | Nissan Chemical Industries Ltd. | Pyrazolopyridine type mevalonolactones useful as pharmaeuticals |
| JP2890448B2 (ja) * | 1988-04-26 | 1999-05-17 | 日産化学工業株式会社 | ピラゾロピリジン系メバロノラクトン類 |
| JP2853227B2 (ja) * | 1988-10-13 | 1999-02-03 | ノバルテイス・アクチエンゲゼルシヤフト | ７置換‐ヘプト‐６‐エン酸、ヘプタン酸及び誘導体並びにそれらの中間体の製法 |
| JPH04270285A (ja) * | 1988-11-14 | 1992-09-25 | Nissan Chem Ind Ltd | ピラゾロピリミジン系メバロノラクトン類 |
| IT1237793B (it) * | 1989-12-21 | 1993-06-17 | Zambon Spa | Composti attivi come inibitori dell'enzima hmg-coa reduttasi |
| US5134155A (en) * | 1991-08-08 | 1992-07-28 | Ortho Pharmaceutical Corporation | Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as HMG-coA reductase inhibitors |
| CA2118795A1 (en) * | 1991-09-20 | 1993-04-01 | John Crosby | Pyranones |
| US5335293A (en) * | 1992-06-16 | 1994-08-02 | Key Technology, Inc. | Product inspection method and apparatus |
| RU2337682C2 (ru) | 2002-11-01 | 2008-11-10 | Такеда Фармасьютикал Компани Лимитед | Средство для профилактики или лечения невропатии |
| KR20070084455A (ko) | 2004-11-23 | 2007-08-24 | 워너-램버트 캄파니 엘엘씨 | 지질혈증 치료용 ｈｍｇ ｃｏ-ａ 환원효소 억제제로서의7-(2ｈ-피라졸-3-일)-3,5-디히드록시-헵탄산 유도체 |
| WO2006087630A2 (en) * | 2005-02-16 | 2006-08-24 | Warner-Lambert Company Llc | OXYPYRAZOLE HMG Co-A REDUCTASE INHIBITORS |
| EP1775299A1 (en) * | 2005-10-05 | 2007-04-18 | LEK Pharmaceuticals D.D. | Process for the synthesis of HMG-CoA reductase inhibitors |
| TW200736225A (en) * | 2006-01-16 | 2007-10-01 | Sankyo Agro Co Ltd | A (3-sulfur substituted phenyl) pyrazole derivative |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1261124B (de) * | 1961-09-22 | 1968-02-15 | Hoechst Ag | Verfahren zur Herstellung von Pyrazolen |
| DE2920933A1 (de) * | 1979-05-23 | 1980-12-04 | Basf Ag | 3-aryl-5-methyl-pyrazol-4-carbonsaeureester enthaltende herbizide |
| US4245106A (en) * | 1979-07-05 | 1981-01-13 | Monsanto Company | Process for the preparation of 1-alkyl-3-aryl-4-pyrazolecarboxylates |
-
1985
- 1985-06-18 WO PCT/EP1985/000293 patent/WO1986000307A2/en active IP Right Grant
- 1985-06-18 AT AT85903248T patent/ATE62906T1/de not_active IP Right Cessation
- 1985-06-18 KR KR1019860700100A patent/KR890001651B1/ko not_active IP Right Cessation
- 1985-06-18 EP EP85903248A patent/EP0200736B1/en not_active Expired - Lifetime
- 1985-06-18 JP JP60502997A patent/JPS61502467A/ja active Pending
- 1985-06-18 DE DE8585903248T patent/DE3582674D1/de not_active Expired - Lifetime
- 1985-06-18 AU AU45466/85A patent/AU573368B2/en not_active Ceased
- 1985-06-18 HU HU853053A patent/HU198711B/hu not_active IP Right Cessation
- 1985-06-20 IL IL75583A patent/IL75583A/xx unknown
- 1985-06-20 PT PT80674A patent/PT80674B/pt not_active IP Right Cessation
- 1985-06-20 NZ NZ212501A patent/NZ212501A/xx unknown
- 1985-06-20 GR GR851510A patent/GR851510B/el unknown
- 1985-06-21 ZA ZA854719A patent/ZA854719B/xx unknown
- 1985-06-21 PL PL1985254121A patent/PL151016B1/pl unknown
- 1985-06-21 ES ES544407A patent/ES8703842A1/es not_active Expired
- 1985-06-21 CA CA000484847A patent/CA1249283A/en not_active Expired
-
1986
- 1986-02-20 FI FI860755A patent/FI860755A/fi not_active Application Discontinuation
- 1986-02-21 DK DK083886A patent/DK157543C/da not_active IP Right Cessation
-
1987
- 1987-09-26 MY MYPI87001978A patent/MY101903A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ212501A (en) | 1988-06-30 |
| AU4546685A (en) | 1986-01-24 |
| ES544407A0 (es) | 1987-03-01 |
| CA1249283A (en) | 1989-01-24 |
| EP0200736A1 (en) | 1986-11-12 |
| MY101903A (en) | 1992-02-15 |
| KR860700253A (ko) | 1986-08-01 |
| PT80674B (en) | 1987-03-17 |
| IL75583A0 (en) | 1985-10-31 |
| PL254121A1 (en) | 1988-07-21 |
| DK83886D0 (da) | 1986-02-21 |
| FI860755A0 (fi) | 1986-02-20 |
| DK157543B (da) | 1990-01-22 |
| FI860755A (fi) | 1986-02-20 |
| KR890001651B1 (ko) | 1989-05-12 |
| AU573368B2 (en) | 1988-06-02 |
| JPS61502467A (ja) | 1986-10-30 |
| WO1986000307A3 (en) | 1986-04-10 |
| EP0200736B1 (en) | 1991-04-24 |
| DK157543C (da) | 1990-06-11 |
| HUT39178A (en) | 1986-08-28 |
| PL151016B1 (en) | 1990-07-31 |
| HU198711B (en) | 1989-11-28 |
| GR851510B (da) | 1985-11-25 |
| WO1986000307A2 (en) | 1986-01-16 |
| PT80674A (en) | 1985-07-01 |
| ZA854719B (en) | 1987-02-25 |
| ES8703842A1 (es) | 1987-03-01 |
| IL75583A (en) | 1989-09-10 |
| DE3582674D1 (de) | 1991-05-29 |
| ATE62906T1 (de) | 1991-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |