DK69281A - PROCEDURE FOR THE PREPARATION OF SALTS OF ALKANCARBOXYLIC ACIDS AND FOR THE PREPARATION OF TOPIC APPLICABLE PHARMACEUTICAL PREPARATIONS CONTAINING THESE SALTS - Google Patents
PROCEDURE FOR THE PREPARATION OF SALTS OF ALKANCARBOXYLIC ACIDS AND FOR THE PREPARATION OF TOPIC APPLICABLE PHARMACEUTICAL PREPARATIONS CONTAINING THESE SALTSInfo
- Publication number
- DK69281A DK69281A DK69281A DK69281A DK69281A DK 69281 A DK69281 A DK 69281A DK 69281 A DK69281 A DK 69281A DK 69281 A DK69281 A DK 69281A DK 69281 A DK69281 A DK 69281A
- Authority
- DK
- Denmark
- Prior art keywords
- ethyl
- groups
- salts
- preparation
- bond
- Prior art date
Links
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- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
Alkanecarboxylic acid salts of the formula <IMAGE> in which R1 is <IMAGE> in which X1 is H, X2 is -CH=CH-C(OCH3)=CH-X4, and X3, together with X4, is a bond, R2 is methyl, and R3, R4 and R5 are ethyl or 2-hydroxyethyl, or one of the groups R3, R4 and R5 is H and the others are ethyl, 2-hydroxyethyl or 3-oxa-1,5-pentylene, or in which R1 is IIa, in which X1 is 2,6-dichloroanilino, X2 and X3 are H, R2 is H, and one of the groups R3, R4 and R5 is H and the others are ethyl, or the groups R3, R4 and R5 are each 2- hydroxyethyl, or in which R1 is <IMAGE> in which X5 is methyl, X6 is a common bond with the methine group of the formula I, X7 is -CH=C(OCH3)-CH=CH- X10, X8, together with X10, is a bond, Y is N, and X9 is p-chlorobenzoyl, R2 is H, and R3, R4 and R5 are hydroxyalkyl or ethyl, or two of the groups R3, R4 and R5 are hydroxyalkyl or ethyl, and the other is H, or one of the groups R3, R4 and R5 is hydroxyalkyl or ethyl, and the third is H, or isomers thereof, are prepared in a known manner. Topically applicable preparations comprising the compound I or isomers thereof or compounds I, in which R1 is the group IIa, in which X1 and X2 are H, X3 is isobutylene, or X1 and X3 are H, and X2 is benzoyl, or X1 is H, X2 is chlorine, and X3 is 3-pyrrolin-1-yl, or in which R1 is the group IIb, in which X5 denotes the common bond with the methine group in the formula I, X6 and X7 are H, X8 is p-methylbenzoyl, Y is N, and X9 is methyl, or X5 is methyl, X6 a common bond with the methine group in the formula I, X7 is -CH=C(F)-CH=CH-X11, X8 is, together with X11, a bond, Y is a carbon atom, and X9 is (p- methanesulphinylphenyl)methylene, and R2 is H, and in which R3, R4 and R5 are each H, an aliphatic group, or two of R3, R4 and R5 are together a divalent optionally substituted, optionally aza-, oxa- or thia-aliphatic group, with at least one of the groups R3, R4 and R5 being different from H, have an excellent anti-inflammatory and/or analgesic effect.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK69281A DK161515C (en) | 1981-02-17 | 1981-02-17 | METHOD OF ANALOGY FOR THE PREPARATION OF DIETHYLAMMONIUM SALT OF O- (2,6-DICHLORANILINO) -PHENYLIC ACETIC ACID |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK69281A DK161515C (en) | 1981-02-17 | 1981-02-17 | METHOD OF ANALOGY FOR THE PREPARATION OF DIETHYLAMMONIUM SALT OF O- (2,6-DICHLORANILINO) -PHENYLIC ACETIC ACID |
DK69281 | 1981-02-17 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK69281A true DK69281A (en) | 1982-08-18 |
DK161515B DK161515B (en) | 1991-07-15 |
DK161515C DK161515C (en) | 1991-12-23 |
Family
ID=8096446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK69281A DK161515C (en) | 1981-02-17 | 1981-02-17 | METHOD OF ANALOGY FOR THE PREPARATION OF DIETHYLAMMONIUM SALT OF O- (2,6-DICHLORANILINO) -PHENYLIC ACETIC ACID |
Country Status (1)
Country | Link |
---|---|
DK (1) | DK161515C (en) |
-
1981
- 1981-02-17 DK DK69281A patent/DK161515C/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK161515C (en) | 1991-12-23 |
DK161515B (en) | 1991-07-15 |
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Legal Events
Date | Code | Title | Description |
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PUP | Patent expired |