DK640388D0 - Pyrimidinderivater - Google Patents

Pyrimidinderivater

Info

Publication number
DK640388D0
DK640388D0 DK640388A DK640388A DK640388D0 DK 640388 D0 DK640388 D0 DK 640388D0 DK 640388 A DK640388 A DK 640388A DK 640388 A DK640388 A DK 640388A DK 640388 D0 DK640388 D0 DK 640388D0
Authority
DK
Denmark
Prior art keywords
pyrimidine
Prior art date
Application number
DK640388A
Other languages
English (en)
Other versions
DK170893B1 (da
DK640388A (da
Inventor
Morio Fujiu
Hideo Ishitsuka
Masanori Miwa
Isao Umeda
Kazuteru Yokose
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK640388D0 publication Critical patent/DK640388D0/da
Publication of DK640388A publication Critical patent/DK640388A/da
Application granted granted Critical
Publication of DK170893B1 publication Critical patent/DK170893B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/067—Pyrimidine radicals with ribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK640388A 1987-11-17 1988-11-16 Nye 5'-deoxy-5-fluorcytidinderivater, en fremgangsmåde til fremstilling deraf, farmaceutiske midler indeholdende sådanne derivater og anvendelse af derivaterne til fremstilling af et antitumormiddel DK170893B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP87116926 1987-11-17
EP87116926 1987-11-17

Publications (3)

Publication Number Publication Date
DK640388D0 true DK640388D0 (da) 1988-11-16
DK640388A DK640388A (da) 1989-05-18
DK170893B1 DK170893B1 (da) 1996-03-04

Family

ID=8197450

Family Applications (1)

Application Number Title Priority Date Filing Date
DK640388A DK170893B1 (da) 1987-11-17 1988-11-16 Nye 5'-deoxy-5-fluorcytidinderivater, en fremgangsmåde til fremstilling deraf, farmaceutiske midler indeholdende sådanne derivater og anvendelse af derivaterne til fremstilling af et antitumormiddel

Country Status (35)

Country Link
US (1) US4966891A (da)
EP (1) EP0316704B1 (da)
JP (1) JPH0678350B2 (da)
KR (1) KR970000241B1 (da)
CN (1) CN1022688C (da)
AR (1) AR247217A1 (da)
AT (1) ATE124951T1 (da)
AU (1) AU619220B2 (da)
CA (1) CA1327358C (da)
CS (1) CS274486B2 (da)
DE (2) DE3854148D1 (da)
DK (1) DK170893B1 (da)
DZ (1) DZ1270A1 (da)
ES (1) ES2074429T3 (da)
FI (1) FI89804C (da)
GR (1) GR3017686T3 (da)
HK (1) HK1003114A1 (da)
HU (1) HU199866B (da)
IE (1) IE883430L (da)
IL (1) IL88363A0 (da)
IS (1) IS1895B (da)
LT (1) LT2185B (da)
LU (1) LU90769I2 (da)
LV (1) LV5624A3 (da)
MC (1) MC1992A1 (da)
MX (1) MX173347B (da)
NL (1) NL300045I2 (da)
NO (2) NO171167C (da)
NZ (1) NZ226923A (da)
PH (1) PH25641A (da)
PT (1) PT89009B (da)
SU (1) SU1736342A3 (da)
UA (1) UA19333A (da)
YU (1) YU47122B (da)
ZA (1) ZA888428B (da)

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WO2009042064A2 (en) 2007-09-21 2009-04-02 Nektar Therapeutics Al, Corporation Oligomer-nucleoside phosphate conjugates
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KR20090122955A (ko) * 2008-01-03 2009-12-01 플러스 케미칼스, 에스.에이. 카페시타빈의 제조 방법
CN102641270A (zh) 2008-06-17 2012-08-22 惠氏有限责任公司 含有hki-272和长春瑞滨的抗肿瘤组合
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US3404144A (en) * 1965-12-23 1968-10-01 Research Corp 1-beta-d-arabinofuranosyl-5-fluorocytosine compounds
GB1379410A (en) * 1971-06-08 1975-01-02 Upjohn Co 1-beta-d-arabino-furanosyl-n4-alpha-aminoacylcytosines
JPS52153977A (en) * 1976-06-11 1977-12-21 Daikin Ind Ltd Synthesis of 5-fluorouracil and its derivatives
US4071680A (en) * 1976-12-20 1978-01-31 Hoffmann-La Roche Inc. 5'-Deoxy-5-fluoropyrimidine nucleosides
CH633810A5 (en) * 1978-01-01 1982-12-31 Hoffmann La Roche Novel nucleosides and process for their preparation
FR2528311B1 (fr) * 1982-06-14 1985-06-14 Synthelabo Compositions pharmaceutiques a base de xylosides et lyxosides de bases puriques et pyrimidiques
JPS61112093A (ja) * 1984-11-05 1986-05-30 Wakunaga Seiyaku Kk ヌクレオチド誘導体

Also Published As

Publication number Publication date
NO2001013I2 (no) 2006-05-01
EP0316704B1 (de) 1995-07-12
KR970000241B1 (ko) 1997-01-08
NZ226923A (en) 1990-10-26
NL300045I1 (nl) 2001-08-01
NO885106L (no) 1989-05-18
CN1033183A (zh) 1989-05-31
CS274486B2 (en) 1991-04-11
LU90769I2 (fr) 2001-07-02
YU209188A (en) 1990-08-31
DE10199027I1 (de) 2001-08-02
JPH0678350B2 (ja) 1994-10-05
YU47122B (sh) 1994-12-28
EP0316704A2 (de) 1989-05-24
LT2185B (lt) 1993-10-15
IE883430L (en) 1989-05-17
EP0316704A3 (en) 1990-11-22
CS747588A2 (en) 1990-09-12
MX173347B (es) 1994-01-03
DZ1270A1 (fr) 2004-09-13
SU1736342A3 (ru) 1992-05-23
ZA888428B (en) 1989-06-28
JPH01153696A (ja) 1989-06-15
HUT48267A (en) 1989-05-29
CN1022688C (zh) 1993-11-10
FI89804C (fi) 1993-11-25
IL88363A0 (en) 1989-06-30
AR247217A1 (es) 1994-11-30
NO171167C (no) 1993-02-03
MX13836A (es) 1993-10-01
IS1895B (is) 2003-10-20
NO885106D0 (no) 1988-11-16
AU2516888A (en) 1989-05-25
DK170893B1 (da) 1996-03-04
CA1327358C (en) 1994-03-01
PT89009B (pt) 1993-02-26
PT89009A (pt) 1988-12-01
NO171167B (no) 1992-10-26
LV5624A3 (lv) 1994-05-10
MC1992A1 (fr) 1989-11-30
ES2074429T3 (es) 1995-09-16
FI885329A (fi) 1989-05-18
GR3017686T3 (en) 1996-01-31
KR890008162A (ko) 1989-07-10
FI885329A0 (fi) 1988-11-17
DE10199027I2 (de) 2002-01-31
NL300045I2 (nl) 2002-01-02
FI89804B (fi) 1993-08-13
US4966891A (en) 1990-10-30
AU619220B2 (en) 1992-01-23
UA19333A (uk) 1997-12-25
ATE124951T1 (de) 1995-07-15
HK1003114A1 (en) 1998-10-09
IS3412A7 (is) 1989-05-18
DE3854148D1 (de) 1995-08-17
DK640388A (da) 1989-05-18
PH25641A (en) 1991-08-21
HU199866B (en) 1990-03-28

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
CTFF Application for supplementary protection certificate (spc) filed

Spc suppl protection certif: CA 2001 00016

Filing date: 20010507

Extension date: 20131116

CTFG Supplementary protection certificate (spc) issued

Free format text: PRODUCT NAME: CAPECITABIN

Spc suppl protection certif: CA 2001 00016

Filing date: 20010507

PUP Patent expired
CUG Supplementary protection certificate (spc) revoked

Spc suppl protection certif: CA 2001 00016