DK639689D0 - Indfoering af dna i celler - Google Patents

Indfoering af dna i celler

Info

Publication number
DK639689D0
DK639689D0 DK639689A DK639689A DK639689D0 DK 639689 D0 DK639689 D0 DK 639689D0 DK 639689 A DK639689 A DK 639689A DK 639689 A DK639689 A DK 639689A DK 639689 D0 DK639689 D0 DK 639689D0
Authority
DK
Denmark
Prior art keywords
replication
cells
introducing dna
origin
dna sequence
Prior art date
Application number
DK639689A
Other languages
English (en)
Inventor
Steen Troels Joergensen
Per Linaa Joergensen
Boerge Krag Diderichsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8148687&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK639689(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to DK639689A priority Critical patent/DK639689D0/da
Publication of DK639689D0 publication Critical patent/DK639689D0/da
Priority to JP50181391A priority patent/JP3162707B2/ja
Priority to DE69013520T priority patent/DE69013520T3/de
Priority to EP91901587A priority patent/EP0506780B2/en
Priority to DK91901587T priority patent/DK0506780T4/da
Priority to AT91901587T priority patent/ATE113077T1/de
Priority to PCT/DK1990/000332 priority patent/WO1991009129A1/en
Priority to ES91901587T priority patent/ES2064077T5/es
Priority to AU70312/91A priority patent/AU643741B2/en
Priority to CA002070676A priority patent/CA2070676A1/en
Priority to FI922812A priority patent/FI112502B/fi
Priority to NO92922381A priority patent/NO922381L/no
Priority to US08/377,891 priority patent/US6280721B1/en
Priority to US08/441,714 priority patent/US5695976A/en
Priority to US08/872,571 priority patent/US6270760B1/en
Priority to US09/060,288 priority patent/US5955367A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • C12N15/902Stable introduction of foreign DNA into chromosome using homologous recombination

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK639689A 1989-12-18 1989-12-18 Indfoering af dna i celler DK639689D0 (da)

Priority Applications (16)

Application Number Priority Date Filing Date Title
DK639689A DK639689D0 (da) 1989-12-18 1989-12-18 Indfoering af dna i celler
CA002070676A CA2070676A1 (en) 1989-12-18 1990-12-18 Stable integration of dna in bacterial genomes
DE69013520T DE69013520T3 (de) 1989-12-18 1990-12-18 Stabile integration von dna in bakterielle genome.
AT91901587T ATE113077T1 (de) 1989-12-18 1990-12-18 Stabile integration von dna in bakterielle genome.
AU70312/91A AU643741B2 (en) 1989-12-18 1990-12-18 Stable integration of DNA in bacterial genomes
EP91901587A EP0506780B2 (en) 1989-12-18 1990-12-18 Stable integration of dna in bacterial genomes
DK91901587T DK0506780T4 (da) 1989-12-18 1990-12-18 Stabil integration af DNA i bakteriegenomer
JP50181391A JP3162707B2 (ja) 1989-12-18 1990-12-18 細菌ゲノムにおけるdnaの安定な組込み
PCT/DK1990/000332 WO1991009129A1 (en) 1989-12-18 1990-12-18 Stable integration of dna in bacterial genomes
ES91901587T ES2064077T5 (es) 1989-12-18 1990-12-18 Integracion estable de adn en genomas bacterianos.
FI922812A FI112502B (fi) 1989-12-18 1992-06-17 DNA:n siirtäminen stabiilisti bakteerien perimään
NO92922381A NO922381L (no) 1989-12-18 1992-06-17 Stabil integrering av dna i bakteriegenomer
US08/377,891 US6280721B1 (en) 1989-12-18 1995-01-25 Production of Bacillus thuringiensis integrants
US08/441,714 US5695976A (en) 1989-12-18 1995-05-15 Stable integration of DNA in bacterial genomes
US08/872,571 US6270760B1 (en) 1989-12-18 1997-06-10 Production of Bacillus thuringiensis integrants
US09/060,288 US5955367A (en) 1989-12-18 1998-04-14 Production of bacillus thuringiensis integrants

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK639689A DK639689D0 (da) 1989-12-18 1989-12-18 Indfoering af dna i celler

Publications (1)

Publication Number Publication Date
DK639689D0 true DK639689D0 (da) 1989-12-18

Family

ID=8148687

Family Applications (2)

Application Number Title Priority Date Filing Date
DK639689A DK639689D0 (da) 1989-12-18 1989-12-18 Indfoering af dna i celler
DK91901587T DK0506780T4 (da) 1989-12-18 1990-12-18 Stabil integration af DNA i bakteriegenomer

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK91901587T DK0506780T4 (da) 1989-12-18 1990-12-18 Stabil integration af DNA i bakteriegenomer

Country Status (11)

Country Link
EP (1) EP0506780B2 (da)
JP (1) JP3162707B2 (da)
AT (1) ATE113077T1 (da)
AU (1) AU643741B2 (da)
CA (1) CA2070676A1 (da)
DE (1) DE69013520T3 (da)
DK (2) DK639689D0 (da)
ES (1) ES2064077T5 (da)
FI (1) FI112502B (da)
NO (1) NO922381L (da)
WO (1) WO1991009129A1 (da)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665711B1 (fr) * 1990-08-08 1993-08-13 Centre Nat Rech Scient Integron de corynebacterie, procede de transformation d'une corynebacterie par ledit integron et corynebacterie obtenue.
IL110299A0 (en) * 1993-07-15 1994-10-21 Novo Nordisk Entotech Inc Formation of and methods for the production of large bacillus thuringiensis crystals with increased pesticidal activity
AU5001496A (en) * 1995-03-22 1996-10-08 Novo Nordisk A/S Introduction of dna into bacillus strains by conjugation
FR2736066B1 (fr) * 1995-06-30 1998-11-20 Ajinomoto Kk Procede d'amplification d'un gene par transposon artificiel, bacterie coryneforme obtenue par ce procede et procede de production d'un acide amine a l'aide de cette bacterie
ATE293359T1 (de) 1997-12-22 2005-05-15 Novozymes As Kohlenhydratoxidase sowie verwendung derselben beim backen
BRPI9911086B1 (pt) 1998-06-10 2016-08-02 Novozymes As composição de limpeza, processo para tratar tecidos a máquina, e uso de uma mananase
JP3958884B2 (ja) 1998-09-11 2007-08-15 株式会社林原生物化学研究所 非還元性糖質生成酵素及びトレハロース遊離酵素ならびに該酵素を用いる糖質の製造方法
DE69932345T2 (de) 1998-10-26 2007-07-19 Novozymes A/S Erstellung und durchmusterung von interessierenden dna-banken in zellen von filamentösen pilzen
EP1297170B1 (en) 2000-06-23 2016-03-02 Novozymes A/S Method for stable chromosomal multi-copy integration of genes
ES2521615T3 (es) 2001-06-06 2014-11-13 Novozymes A/S Endo-beta-1,4-glucanasa
AU2003214034A1 (en) 2002-04-10 2003-11-17 Novozymes A/S Bacillus licheniformis mutant host cell
EP1696035A3 (en) 2002-04-10 2008-04-02 Novozymes A/S Improved bacillus host cell
AU2003223928A1 (en) * 2002-05-07 2003-11-11 Novozymes A/S Homologous recombination into bacterium for the generation of polynucleotide libraries
MXPA05006071A (es) 2002-12-11 2005-09-30 Novozymes As Composicion detergente.
EP1694846B1 (en) 2003-12-10 2014-10-01 Novozymes A/S A cell with improved secretion mediated by mrga protein or homologue
CN101006174B (zh) 2004-06-21 2010-05-26 诺维信公司 以相同取向稳定保持的至少两个orf的多拷贝
CN101595214B (zh) 2006-11-29 2013-06-12 诺维信股份有限公司 改进向细菌细胞中导入dna的方法
DK2104739T3 (da) 2006-12-21 2013-10-07 Novozymes Inc Modificerede messenger-RNA-stabiliseringssekvenser til ekspression af gener i bakterieceller
US20120329090A1 (en) 2009-12-21 2012-12-27 Novozymes A/S Methods for Producing Heterologous Polypeptides in Thiol-Disulfide Oxidoreductase-Deficient Bacterial Mutant Cells
CN109804072A (zh) 2016-10-25 2019-05-24 诺维信公司 地衣芽孢杆菌中flp介导的基因组整合
CN110945013A (zh) 2017-07-21 2020-03-31 巴斯夫欧洲公司 异源表达的启动子
WO2019016051A1 (en) 2017-07-21 2019-01-24 Basf Se PROCESS FOR TRANSFORMING BACTERIAL CELLS
CN111511908A (zh) 2017-11-10 2020-08-07 诺维信公司 温度敏感性cas9蛋白
US20210017544A1 (en) 2017-12-22 2021-01-21 Novozymes A/S Counter-Selection by Inhibition of Conditionally Essential Genes
WO2020156903A1 (en) 2019-01-30 2020-08-06 Novozymes A/S Cognate foldase co-expression
WO2020169563A1 (en) 2019-02-20 2020-08-27 Basf Se Industrial fermentation process for bacillus using defined medium and magnesium feed
EP3927809A1 (en) 2019-02-20 2021-12-29 Basf Se Industrial fermentation process for bacillus using defined medium and trace element feed
CN113785056A (zh) 2019-03-08 2021-12-10 诺维信公司 改善蛋白酶表达的手段和方法
CN113939588A (zh) 2019-05-15 2022-01-14 诺维信公司 温度敏感性的rna指导的内切核酸酶
WO2020260061A1 (en) 2019-06-25 2020-12-30 Novozymes A/S Counter-selection by inhibition of conditionally essential genes
EP3994273A1 (en) 2019-07-02 2022-05-11 Basf Se Method for preparing a fermentation medium
EP4189103A1 (en) 2020-07-28 2023-06-07 Basf Se Industrial fermentation process for bacillus using temperature shift
US20230272333A1 (en) 2020-07-28 2023-08-31 Basf Se Industrial fermentation process for bacillus using partial harvest
CN116234922A (zh) 2020-07-28 2023-06-06 巴斯夫欧洲公司 使用进料速率变化的芽孢杆菌工业发酵工艺
US20240060110A1 (en) 2020-10-07 2024-02-22 Basf Se Bacillus cell with reduced lipase and/or esterase side activities
CN117693587A (zh) 2021-06-24 2024-03-12 巴斯夫欧洲公司 具有改变的RemA/RemB蛋白的改良芽孢杆菌宿主细胞
BR112023027009A2 (pt) 2021-06-24 2024-03-12 Basf Se Célula hospedeira modificada de bacillus licheniformis, e, métodos para produzir um composto de interesse e para aumentar a pureza de um composto de interesse
CN117730090A (zh) 2021-07-13 2024-03-19 诺维信公司 重组角质酶表达
WO2023247514A1 (en) 2022-06-22 2023-12-28 Novozymes A/S Recombinant mannanase expression
WO2024028340A1 (en) 2022-08-02 2024-02-08 Basf Se Stabilized protein production process using bacillus host cells with salt feed

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631257A (en) * 1978-12-26 1986-12-23 Cetus Corporation Stable high copy number plasmids
US4401761A (en) * 1981-01-26 1983-08-30 The Upjohn Company Process for stabilizing plasmids by deletion of DNA

Also Published As

Publication number Publication date
JP3162707B2 (ja) 2001-05-08
DE69013520D1 (de) 1994-11-24
AU643741B2 (en) 1993-11-25
FI922812A (fi) 1992-06-17
EP0506780B2 (en) 2004-01-02
AU7031291A (en) 1991-07-18
FI922812A0 (fi) 1992-06-17
JPH05502162A (ja) 1993-04-22
WO1991009129A1 (en) 1991-06-27
FI112502B (fi) 2003-12-15
DE69013520T2 (de) 1995-05-04
DK0506780T3 (da) 1995-04-18
EP0506780A1 (en) 1992-10-07
DE69013520T3 (de) 2004-09-23
NO922381L (no) 1992-08-17
NO922381D0 (no) 1992-06-17
ES2064077T3 (es) 1995-01-16
ATE113077T1 (de) 1994-11-15
ES2064077T5 (es) 2004-09-01
DK0506780T4 (da) 2004-04-26
CA2070676A1 (en) 1991-06-19
EP0506780B1 (en) 1994-10-19

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