DK628087D0 - Diazepinderivater - Google Patents

Diazepinderivater

Info

Publication number: DK628087D0
Authority: DK; Denmark
Prior art keywords: diazepine
Prior art date: 1986-12-15

Application number

DK628087A

Other languages

English (en)

Other versions

DK628087A (da

Inventor

Geoffrey Lawton

Sally Redshaw

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-12-15

Filing date

1987-11-30

Publication date

1987-11-30

1987-11-30 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1987-11-30 Publication of DK628087D0 publication Critical patent/DK628087D0/da

1988-06-16 Publication of DK628087A publication Critical patent/DK628087A/da

Links

LRANPJDWHYRCER-UHFFFAOYSA-N 1,2-diazepine Chemical compound N1C=CC=CC=N1 LRANPJDWHYRCER-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK628087A 1986-12-15 1987-11-30 Diazepinderivater DK628087A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB868629875A GB8629875D0 (en)	1986-12-15	1986-12-15	Pyridazodiazepine derivatives

Publications (2)

Publication Number	Publication Date
DK628087D0 true DK628087D0 (da)	1987-11-30
DK628087A DK628087A (da)	1988-06-16

Family

ID=10609005

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK628087A DK628087A (da)	1986-12-15	1987-11-30	Diazepinderivater

Country Status (17)

Country	Link
US (2)	US4757069A (da)
EP (1)	EP0271795A3 (da)
JP (1)	JPS63162693A (da)
KR (1)	KR880007538A (da)
AU (1)	AU602546B2 (da)
CA (1)	CA1291478C (da)
DK (1)	DK628087A (da)
FI (1)	FI85482C (da)
GB (1)	GB8629875D0 (da)
HU (1)	HU198492B (da)
IL (1)	IL84765A (da)
MC (1)	MC1879A1 (da)
NO (1)	NO166083C (da)
NZ (1)	NZ222825A (da)
PH (1)	PH23813A (da)
PT (1)	PT86365B (da)
ZA (1)	ZA879229B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5430145A (en) *	1990-10-18	1995-07-04	Merrell Dow Pharmaceuticals Inc.	Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
US5308841A (en) *	1990-12-21	1994-05-03	Merrell Dow Pharmaceuticals Inc.	Amino and nitro containing tricyclic compounds useful as inhibitors of ACE
EP0534363B1 (en) *	1991-09-27	1997-07-09	Merrell Pharmaceuticals Inc.	Novel 2-substituted indane-2-mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
US5457196A (en) *	1991-09-27	1995-10-10	Merrell Dow Pharmaceuticals Inc.	2-substituted indane-2-carboxyalkyl derivatives useful as inhibitors of enkephalinase and ACE
US5455242A (en) *	1991-09-27	1995-10-03	Merrell Dow Pharmaceuticals Inc.	Carboxyalkyl tricyclic derivatives useful as inhibitors of enkephalinase and ace
DE69317764T2 (de) *	1992-02-14	1998-07-30	Merrell Pharmaceuticals Inc., Cincinnati, Ohio	Aminoacetylmercaptoacetylamid derivate mit enkephalinase- und ace-hemmwirkung
EP0640086B1 (en) *	1992-05-15	1999-08-04	Merrell Pharmaceuticals Inc.	MERCAPTOACETYLAMIDO PYRIDAZO[ 1,2-a][1,2]DIAZEPINE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE
US5420271A (en) *	1992-08-24	1995-05-30	Merrell Dow Pharmaceuticals, Inc.	2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
JP3420766B2 (ja) *	1992-10-30	2003-06-30	メレルダウファーマス−ティカルズインコーポレイテッド	エンケファリナーゼ及びａｃｅの阻害剤として有用な新規なメルカプトアセチルアミド二環式ラクタム誘導体類
US5530013A (en) *	1994-02-14	1996-06-25	American Home Products Corporation	Venlafaxine in the inducement of cognition enhancement
ATE177098T1 (de) *	1994-02-14	1999-03-15	Merrell Pharma Inc	Mercaptoacetylamid disulfidderivate als enkephalinase und ace inhibitoren
WO1995021854A1 (en) *	1994-02-14	1995-08-17	Merrell Pharmaceuticals Inc.	Novel mercaptoacetylamido 1,3,4,5-tetrahydro-benzo[c]azepin-3-one disulfide derivatives useful as inhibitors of enkephalinase and ace
DK0745081T3 (da) *	1994-02-14	2002-05-21	Merrell Pharma Inc	Indan-2-mercaptoacetylamiddisulfidderivater, der er anvendelige som enkephalinase-inhibitorer
CA2183314C (en) *	1994-02-14	1999-08-31	Gary A. Flynn	Novel 2-substituted indane-2-mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace
US5484783A (en) *	1994-03-24	1996-01-16	Merrell Dow Pharmaceuticals Inc.	Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives
EP0751783B1 (en) *	1994-03-24	2000-02-02	Merrell Pharmaceuticals Inc.	Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic use of aminoacetylmercapto derivatives
DE69531489T2 (de) *	1994-03-24	2004-04-08	Merrell Pharmaceuticals Inc., Cincinnati	Cholesterin senkende mercaptoacetylamiddisulfidderivate
AU2000265534A1 (en) *	2000-02-17	2001-08-27	China Petroleum And Chemical Corporation	Multiblock copolymer the preparing method thereof
GB0119305D0 (en)	2001-04-12	2001-10-03	Aventis Pharma Gmbh	Mercaptoacetylamide derivatives,a process for their preparation and their use
IE20070935A1 (en) *	2007-12-21	2009-06-24	Trinity College Dublin	Guanidine based compounds and their use in the treatment of mental and neurological disorders.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4092438A (en) *	1977-04-29	1978-05-30	Carnation Company	Non-dairy coffee whitener containing acetate salt
GB2128984B (en) *	1982-05-12	1985-05-22	Hoffmann La Roche	Diaza-bicyclic compounds
GB8320764D0 (en) *	1983-08-02	1983-09-01	Rhodes Joseph Ltd	Bending machines
US4692438A (en) *	1984-08-24	1987-09-08	Hoffmann-La Roche Inc.	Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity
EP0187037A3 (en) *	1984-12-21	1988-03-23	Takeda Chemical Industries, Ltd.	Piperidine derivatives, their production and use

1986
- 1986-12-15 GB GB868629875A patent/GB8629875D0/en active Pending
1987
- 1987-11-24 US US07/124,749 patent/US4757069A/en not_active Expired - Fee Related
- 1987-11-30 DK DK628087A patent/DK628087A/da not_active Application Discontinuation
- 1987-12-07 EP EP87118047A patent/EP0271795A3/de not_active Ceased
- 1987-12-07 NZ NZ222825A patent/NZ222825A/en unknown
- 1987-12-08 CA CA000553720A patent/CA1291478C/en not_active Expired - Fee Related
- 1987-12-08 ZA ZA879229A patent/ZA879229B/xx unknown
- 1987-12-09 AU AU82254/87A patent/AU602546B2/en not_active Ceased
- 1987-12-09 IL IL84765A patent/IL84765A/xx unknown
- 1987-12-10 MC MC871934A patent/MC1879A1/xx unknown
- 1987-12-11 HU HU875592A patent/HU198492B/hu unknown
- 1987-12-14 JP JP62314308A patent/JPS63162693A/ja active Pending
- 1987-12-14 NO NO875200A patent/NO166083C/no unknown
- 1987-12-14 FI FI875483A patent/FI85482C/fi not_active IP Right Cessation
- 1987-12-14 KR KR870014258A patent/KR880007538A/ko not_active Application Discontinuation
- 1987-12-14 PH PH36217A patent/PH23813A/en unknown
- 1987-12-15 PT PT86365A patent/PT86365B/pt not_active IP Right Cessation
1988
- 1988-03-17 US US07/169,266 patent/US4782149A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0271795A2 (de)	1988-06-22
IL84765A (en)	1991-06-30
FI875483A (fi)	1988-06-16
KR880007538A (ko)	1988-08-27
CA1291478C (en)	1991-10-29
HU198492B (en)	1989-10-30
JPS63162693A (ja)	1988-07-06
PH23813A (en)	1989-11-23
GB8629875D0 (en)	1987-01-28
AU8225487A (en)	1988-06-16
PT86365B (pt)	1990-11-20
US4757069A (en)	1988-07-12
NO875200L (no)	1988-06-16
NZ222825A (en)	1990-11-27
FI85482B (fi)	1992-01-15
IL84765A0 (en)	1988-05-31
EP0271795A3 (de)	1989-08-09
DK628087A (da)	1988-06-16
FI875483A0 (fi)	1987-12-14
ZA879229B (en)	1988-06-15
NO166083C (no)	1991-05-29
PT86365A (en)	1988-01-01
NO875200D0 (no)	1987-12-14
MC1879A1 (fr)	1989-01-24
AU602546B2 (en)	1990-10-18
US4782149A (en)	1988-11-01
HUT47279A (en)	1989-02-28
NO166083B (no)	1991-02-18
FI85482C (fi)	1992-04-27

Legal Events

Date	Code	Title	Description
1994-07-25	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
AT399804B (de)	1995-07-25	Sportschuh
DK126388D0 (da)	1988-03-09	Referenceelektrode
DK628087A (da)	1988-06-16	Diazepinderivater
DK190789D0 (da)	1989-04-19	Diazepinderivater
ATA246886A (de)	1988-01-15	Schachtsystem
ATA48386A (de)	1988-08-15	Kranbahn
DK153317C (da)	1988-11-14	Vaeskecontainer
BR8603768A (pt)	1988-05-17	Perspectivografo
BR8603659A (pt)	1988-02-09	Mini-infiltrometro
ATA179487A (de)	1990-12-15	Maishaecksler
BR6602300U (pt)	1987-08-04	Sofa-cama-armario
BR8604019A (pt)	1988-04-19	Doc-junior dossie infanto-juvenil
BR8601218A (pt)	1987-10-27	Lencol casulo
BR8601107A (pt)	1987-10-27	Eliteste
BR8600774A (pt)	1987-09-08	Popette
BR8600545A (pt)	1987-09-01	Varal retractil
BR8600456A (pt)	1987-09-01	Mini-pasteurizador
BR8600446A (pt)	1987-09-01	Distorcedor
BR8600416A (pt)	1987-09-01	Umidificador-ii
BR8600285A (pt)	1987-09-01	Hidrovalvula
BR6602608U (pt)	1988-07-19	Oculos-tiara
BR6601110U (pt)	1988-03-29	Regua-multi-uso
BR6601490U (pt)	1988-05-03	Aiveca
BR6601361U (pt)	1988-04-12	Marmiteira
BR6601345U (pt)	1988-04-12	Lousa magica