DK586685A - Antitumor-aktivt stof, fremgangsmaade til dets fremstilling, laegemiddel indeholdende stoffet, gen kodende for stoffet, vektor indeholdende genet samt rekombinant mikroorganisme - Google Patents
Antitumor-aktivt stof, fremgangsmaade til dets fremstilling, laegemiddel indeholdende stoffet, gen kodende for stoffet, vektor indeholdende genet samt rekombinant mikroorganismeInfo
- Publication number
- DK586685A DK586685A DK586685A DK586685A DK586685A DK 586685 A DK586685 A DK 586685A DK 586685 A DK586685 A DK 586685A DK 586685 A DK586685 A DK 586685A DK 586685 A DK586685 A DK 586685A
- Authority
- DK
- Denmark
- Prior art keywords
- substance
- genet
- antitumor
- procedure
- manufacturing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/545—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP27120784 | 1984-12-21 | ||
JP27120784 | 1984-12-21 | ||
JP13828085 | 1985-06-24 | ||
JP13828085 | 1985-06-24 | ||
JP13828185 | 1985-06-24 | ||
JP13828185 | 1985-06-24 | ||
JP22088285 | 1985-10-03 | ||
JP22088285 | 1985-10-03 | ||
JP28323885 | 1985-12-16 | ||
JP60283238A JPS62142121A (ja) | 1985-12-16 | 1985-12-16 | 抗腫瘍活性物質 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK586685D0 DK586685D0 (da) | 1985-12-17 |
DK586685A true DK586685A (da) | 1986-06-22 |
DK172052B1 DK172052B1 (da) | 1997-09-29 |
Family
ID=27527509
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK586685A DK172052B1 (da) | 1984-12-21 | 1985-12-17 | Antitumor-aktivt stof, fremgangsmåde til dets fremstilling, lægemiddel indeholdende stoffet, gen kodende for stoffet, vektor indeholdende genet samt rekombinant mikroorganisme transformet med en sådan vektor |
Country Status (5)
Country | Link |
---|---|
US (1) | US4898818A (da) |
EP (1) | EP0187991B1 (da) |
KR (1) | KR930012106B1 (da) |
DE (2) | DE187991T1 (da) |
DK (1) | DK172052B1 (da) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0569687B1 (en) * | 1984-05-18 | 2002-08-21 | New England Medical Center Hospitals, Inc. | Human IL-1 cDNA sequences encoding biologically-active human IL-1 proteins |
US5998578A (en) * | 1984-05-18 | 1999-12-07 | New England Medical Center Hospitals, Inc. | Biologically active fragments of IL-1β |
CA1341433C (en) * | 1984-06-19 | 2003-06-24 | Douglas P. Cerretti | Purification of interleukin 1 |
JP2583770B2 (ja) | 1986-09-17 | 1997-02-19 | 大塚製薬株式会社 | 遺伝子 |
DK590387A (da) * | 1986-11-13 | 1988-05-14 | Otsuka Pharma Co Ltd | Antistoffer mod interleukin-1 |
US5047505A (en) * | 1987-01-27 | 1991-09-10 | Du Pont Merck Pharmaceutical Company | High level expression in E. coli of soluble mature HIL-1beta and derivatives with altered biological activity |
EP0644203A1 (en) * | 1988-07-29 | 1995-03-22 | Otsuka Pharmaceutical Co., Ltd. | IL-1alpha derivatives and medicament for treating thrombocytopenia |
FR2636231A1 (fr) * | 1988-09-09 | 1990-03-16 | Sanofi Sa | Cellules eucaryotes recombinees productrices d'interleukine-1 (beta) mature n-glycosylee, procede et vecteurs necessaires pour leur obtention et procede d'obtention d'interleukine-1 (beta) mature n-glycosylee |
EP0364778B1 (en) * | 1988-10-01 | 1996-03-13 | Otsuka Pharmaceutical Co., Ltd. | Antibody against interleukin-1beta |
US5649904A (en) * | 1988-10-07 | 1997-07-22 | Sandoz Ltd. | Method of treating cancer with a fully myeloablative regimen of chemotherapy, radiation or both |
DE3907244A1 (de) * | 1989-03-07 | 1990-09-13 | Knoll Ag | Erzeugnisse, enthaltend ein lithiumsalz und einen tumor-nekrose-faktor |
DE3922089A1 (de) * | 1989-05-09 | 1990-12-13 | Basf Ag | Neue proteine und ihre herstellung |
US6262239B1 (en) | 1989-05-18 | 2001-07-17 | Yeda Research And Development Co., Ltd. | TNF receptor-specific antibodies |
US6232446B1 (en) | 1989-05-18 | 2001-05-15 | Yeda Research And Development Co. Ltd. | TNF ligands |
US5849282A (en) * | 1990-05-09 | 1998-12-15 | Otsuka Pharmaceutical Co., Ltd. | Method of treating colon, renal, and lung carcinomas with γ-interferon and Ser71 !-interleukin-1β |
US5723117A (en) * | 1990-08-10 | 1998-03-03 | Otsuka Pharmaceutical Co., Ltd. | Use of interleukin-1 (IL-1) to inhibit development of hepatitis |
US6446032B1 (en) * | 1990-09-21 | 2002-09-03 | Massachusetts Institute Of Technology | Designing compounds specifically inhibiting ribonucleic acid by binding to the minor groove |
GB9112553D0 (en) * | 1991-06-11 | 1991-07-31 | Wellcome Found | Fusion proteins |
US7276335B1 (en) * | 1993-09-29 | 2007-10-02 | Massachusetts Institute Of Technology | Designing compounds specifically inhibiting ribonucleic acid function |
US6120770A (en) * | 1997-09-12 | 2000-09-19 | University Of Notre Dame Du Lac | Plasmodium proteins useful for preparing vaccine compositions |
GB9916630D0 (en) * | 1999-07-16 | 1999-09-15 | Univ Manchester | Molecules derived from interleukins |
GB0525866D0 (en) * | 2005-12-20 | 2006-02-01 | Cambridge Microbial Technologi | Chemical induction of quiescence in cells |
EP2598526B1 (en) | 2010-07-29 | 2018-09-05 | Eleven Biotherapeutics, Inc. | Chimeric il-1 receptor type i agonists and antagonists |
SG10201707477SA (en) | 2013-03-13 | 2017-10-30 | Eleven Biotherapeutics Inc | Chimeric cytokine formulations for ocular delivery |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE56026B1 (en) * | 1982-10-19 | 1991-03-27 | Cetus Corp | Cysteine-depleted muteins of biologically active proteins |
FR2550802B1 (fr) * | 1983-08-17 | 1986-04-11 | Inst Nat Sante Rech Med | Procede de production d'interleukine 1 humaine et medicaments correspondants |
JPS60149386A (ja) * | 1984-01-17 | 1985-08-06 | Dainippon Pharmaceut Co Ltd | インタ−ロイキン1をコ−ドする伝令リボ核酸及びその調製法 |
CA1341401C (en) * | 1984-03-23 | 2002-11-26 | Adriano Fontana | Immunosuppressant factor derived from human glioblastoma cells |
EP0155433A1 (en) * | 1984-03-23 | 1985-09-25 | Adriano Fontana | Immunosuppressant factor |
EP0569687B1 (en) * | 1984-05-18 | 2002-08-21 | New England Medical Center Hospitals, Inc. | Human IL-1 cDNA sequences encoding biologically-active human IL-1 proteins |
US4762914A (en) * | 1984-05-18 | 1988-08-09 | Auron Philip E | Truncated protein of interleukin-1 |
DE3587669T2 (de) * | 1984-05-18 | 1994-03-31 | Massachusetts Inst Technology | Menschliche IL-1-cDNS-Sequenzen die für biologisch aktive menschliche IL-1-Proteine kodieren. |
CA1341433C (en) * | 1984-06-19 | 2003-06-24 | Douglas P. Cerretti | Purification of interleukin 1 |
EP0188920B1 (en) * | 1984-12-25 | 1993-09-29 | Dainippon Pharmaceutical Co., Ltd. | Interleukin 1 and its derivative |
AU577856B2 (en) * | 1985-01-17 | 1988-10-06 | Immunex Corporation | Cloning and characterization of the human interleukin 1 gene |
DE3683186D1 (de) * | 1985-04-25 | 1992-02-13 | Hoffmann La Roche | Rekombinantes humaninterleukin-1. |
-
1985
- 1985-12-17 DK DK586685A patent/DK172052B1/da not_active IP Right Cessation
- 1985-12-19 US US06/810,776 patent/US4898818A/en not_active Expired - Lifetime
- 1985-12-20 DE DE198585116344T patent/DE187991T1/de active Pending
- 1985-12-20 DE DE85116344T patent/DE3586050D1/de not_active Expired - Fee Related
- 1985-12-20 EP EP85116344A patent/EP0187991B1/en not_active Expired - Lifetime
- 1985-12-21 KR KR1019850009675A patent/KR930012106B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0187991A2 (en) | 1986-07-23 |
KR930012106B1 (ko) | 1993-12-24 |
EP0187991A3 (en) | 1988-03-16 |
DK172052B1 (da) | 1997-09-29 |
DK586685D0 (da) | 1985-12-17 |
KR860005022A (ko) | 1986-07-16 |
DE187991T1 (de) | 1987-04-30 |
US4898818A (en) | 1990-02-06 |
EP0187991B1 (en) | 1992-05-13 |
DE3586050D1 (da) | 1992-06-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |