DK531582A - PROCEDURE FOR PREPARING DERIVATIVES OF 2-PHENYL MORPHOLINE - Google Patents

PROCEDURE FOR PREPARING DERIVATIVES OF 2-PHENYL MORPHOLINE Download PDF

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Publication number
DK531582A
DK531582A DK531582A DK531582A DK531582A DK 531582 A DK531582 A DK 531582A DK 531582 A DK531582 A DK 531582A DK 531582 A DK531582 A DK 531582A DK 531582 A DK531582 A DK 531582A
Authority
DK
Denmark
Prior art keywords
morpholine
phenyl
procedure
acid addition
addition salts
Prior art date
Application number
DK531582A
Other languages
Danish (da)
Inventor
Louis Lafon
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of DK531582A publication Critical patent/DK531582A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Claims for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE 2-phenyl-morpholine derivative, useful in particular in therapeutics, characterized in that it is selected from the group constituted by : (i) the 2-phenyl-4-ethyl-morpholine and its acid addition salts, and (ii) the 2-o-tolyl-4-methyl-morpholine and its acid addition salts. 1. Claims for the Contracting State : AT Use of a 2-phenyl-morpholine derivative selected from the group constituted by : (i) 2-phenyl-4-ethyl-morpholine and its acid addition salts, and (ii) 2-o-tolyl-4-methyl-morpholine and its acid addition salts, for the preparation of a drug.
DK531582A 1981-12-01 1982-11-30 PROCEDURE FOR PREPARING DERIVATIVES OF 2-PHENYL MORPHOLINE DK531582A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8122507A FR2517305B1 (en) 1981-12-01 1981-12-01 NOVEL 2-PHENYL-MORPHOLINE DERIVATIVES AND THEIR USE IN THERAPEUTICS

Publications (1)

Publication Number Publication Date
DK531582A true DK531582A (en) 1983-06-02

Family

ID=9264557

Family Applications (1)

Application Number Title Priority Date Filing Date
DK531582A DK531582A (en) 1981-12-01 1982-11-30 PROCEDURE FOR PREPARING DERIVATIVES OF 2-PHENYL MORPHOLINE

Country Status (12)

Country Link
EP (1) EP0080940B1 (en)
JP (1) JPS58103377A (en)
AT (1) ATE18043T1 (en)
AU (1) AU9100482A (en)
CA (1) CA1189861A (en)
DE (1) DE3269247D1 (en)
DK (1) DK531582A (en)
ES (1) ES8308317A1 (en)
FR (1) FR2517305B1 (en)
GR (1) GR77037B (en)
IE (1) IE54330B1 (en)
ZA (1) ZA828758B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2553410B1 (en) * 1983-10-14 1986-05-16 Lafon Labor NOVEL 2-TOLYL-MORPHOLINE DERIVATIVES USEFUL IN THERAPEUTICS
FR2564462B1 (en) * 1984-05-16 1986-11-21 Lafon Labor 2-PHENYL-MORPHOLINE DERIVATIVES USEFUL IN THERAPEUTICS
GB9108629D0 (en) * 1991-04-23 1991-06-12 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use
AU3364493A (en) * 1992-01-28 1993-09-01 Smithkline Beecham Plc Compounds as calcium channel antagonists
US7294637B2 (en) 2000-09-11 2007-11-13 Sepracor, Inc. Method of treating addiction or dependence using a ligand for a monamine receptor or transporter
AU2001290873B2 (en) 2000-09-11 2006-07-27 Sepracor Inc. Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2835669A (en) * 1958-05-20 Process for the production of substi-
GB851311A (en) * 1958-04-02 1960-10-12 Geigy Ag J R Morpholine compounds and their production
FR1535615A (en) * 1967-06-26 1968-08-09 Ct Europ De Rech S Mauvernay Process for obtaining tetrahydro-1, 4-oxazines substituted in 2, 4 and in 2, 2, 4
FR2471378A1 (en) * 1979-12-14 1981-06-19 Lafon Labor Alkylated 2:phenyl morpholine derivs. - having antidepressant and cardiovascular activity, prepd. by cyclising hydroxyalkyl phenyl ethanol(s)

Also Published As

Publication number Publication date
IE822840L (en) 1983-06-01
JPS58103377A (en) 1983-06-20
EP0080940A3 (en) 1983-07-06
CA1189861A (en) 1985-07-02
FR2517305B1 (en) 1985-10-25
IE54330B1 (en) 1989-08-30
FR2517305A1 (en) 1983-06-03
ES517779A0 (en) 1983-08-16
JPH0254831B2 (en) 1990-11-22
AU9100482A (en) 1983-06-09
EP0080940A2 (en) 1983-06-08
ATE18043T1 (en) 1986-03-15
ZA828758B (en) 1983-09-28
EP0080940B1 (en) 1986-02-19
GR77037B (en) 1984-09-04
ES8308317A1 (en) 1983-08-16
DE3269247D1 (en) 1986-03-27

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Legal Events

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AHS Application shelved for other reasons than non-payment