DK499385D0 - Piperazinforbindelser - Google Patents
PiperazinforbindelserInfo
- Publication number
- DK499385D0 DK499385D0 DK499385A DK499385A DK499385D0 DK 499385 D0 DK499385 D0 DK 499385D0 DK 499385 A DK499385 A DK 499385A DK 499385 A DK499385 A DK 499385A DK 499385 D0 DK499385 D0 DK 499385D0
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- heterocyclic
- protected
- paf
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848427735A GB8427735D0 (en) | 1984-11-02 | 1984-11-02 | Piperazine compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK499385D0 true DK499385D0 (da) | 1985-10-30 |
| DK499385A DK499385A (da) | 1986-05-03 |
Family
ID=10569141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK499385A DK499385A (da) | 1984-11-02 | 1985-10-30 | Piperazinforbindelser |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0181152B1 (da) |
| KR (1) | KR860004032A (da) |
| AT (1) | ATE46335T1 (da) |
| CA (1) | CA1257265A (da) |
| DE (1) | DE3572978D1 (da) |
| DK (1) | DK499385A (da) |
| ES (1) | ES8702903A1 (da) |
| GB (1) | GB8427735D0 (da) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4806538A (en) * | 1984-11-02 | 1989-02-21 | Fujisawa Pharmaceutical Co., Ltd. | Piperazine compound as PAF-antagonist |
| US4694081A (en) * | 1985-09-23 | 1987-09-15 | Monsanto Company | Process to prepare 2,5-diketopiperazines |
| DK181687A (da) * | 1986-04-23 | 1987-10-24 | Fujisawa Pharmaceutical Co | Piperazinderivater og fremgangsmaade til fremstiling deraf |
| DE3880231T2 (de) * | 1987-08-11 | 1993-10-07 | Otsuka Pharma Co Ltd | Pyrazinoxid-Verbindung aus NF-1616-904, diese enthaltende Arzneimittelzubereitung und Verfahren zu ihrer Herstellung. |
| DE3830096A1 (de) * | 1988-09-03 | 1990-03-15 | Hoechst Ag | Piperazindione mit psychotroper wirkung |
| GB8823776D0 (en) * | 1988-10-11 | 1988-11-16 | Scras | New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines |
| GB8823775D0 (en) * | 1988-10-11 | 1988-11-16 | Scras | New 2-carbonyl substituted n n'-di-(trimethoxybenzoyl)piperazines |
| US5238938A (en) * | 1989-02-10 | 1993-08-24 | Otsuka Pharmaceutical Co., Ltd. | Indole derivatives |
| DE69029231T2 (de) * | 1989-02-10 | 1997-03-20 | Otsuka Pharma Co Ltd | Indolderivate, ihre herstellung und diese enthaltendes arzneimittel zum verhindern und behandeln von nephritis |
| DE3909379A1 (de) * | 1989-03-22 | 1990-09-27 | Cassella Ag | Thienylpiperazine, verfahren zu ihrer herstellung, ihre verwendung sowie diese enthaltende arzneimittel und deren herstellung |
| JP2599665B2 (ja) * | 1991-05-01 | 1997-04-09 | 大塚製薬株式会社 | ピラジン誘導体 |
| US5990112A (en) * | 1996-06-18 | 1999-11-23 | Affymax Technologies N.V. | Inhibitors of metalloproteases pharmaceutical compositions comprising same and methods of their use |
| FR2722787B1 (fr) * | 1994-07-21 | 1996-10-11 | Univ Claude Bernard Lyon | Composes a activite anthelminthique: dicetopiperazines, precurseurs et analogues |
| US5932579A (en) | 1996-06-18 | 1999-08-03 | Affymax Technologies N.V. | Collagenase-1 and stromelysin-1 inhibitors, pharmaceutical compositions comprising same and methods of their use |
| JP5048201B2 (ja) | 2000-08-04 | 2012-10-17 | ディーエムアイ バイオサイエンシズ インコーポレイテッド | ジケトピペラジン類の使用方法とジケトピペラジン類を含む組成物 |
| AR058408A1 (es) | 2006-01-02 | 2008-01-30 | Basf Ag | Compuestos de piperazina con accion herbicida |
| AU2007280995C1 (en) * | 2006-08-04 | 2013-05-23 | Manus Pharmaceuticals (Canada) Ltd. | Multifunctional bioactive compounds |
| CN108947978B (zh) * | 2017-05-22 | 2020-12-01 | 首都医科大学 | 3R-吲哚甲基-6R-Tyr修饰的哌嗪-2,5-二酮，其合成，活性和应用 |
| CN108947979B (zh) * | 2017-05-22 | 2020-10-16 | 首都医科大学 | 3r-吲哚甲基-6r-极性氨基酸修饰的哌嗪-2,5-二酮，其合成，活性和应用 |
| CN108976203B (zh) * | 2017-05-31 | 2020-10-16 | 首都医科大学 | 3S-吲哚甲基-6R-Lys修饰的哌嗪-2,5-二酮，其合成，活性和应用 |
| CN108976206B (zh) * | 2017-06-01 | 2020-07-28 | 首都医科大学 | 3S-吲哚甲基-6R-Glu修饰的哌嗪-2,5-二酮，其合成，活性和应用 |
| CN108976205B (zh) * | 2017-06-01 | 2020-07-28 | 首都医科大学 | 3s-吲哚甲基-6r-极性氨基酸修饰的哌嗪-2,5-二酮，其合成，活性和应用 |
| CN108976209B (zh) * | 2017-06-01 | 2020-07-28 | 首都医科大学 | 3s-吲哚甲基-6r-含n杂环氨基酸修饰的哌嗪-2,5-二酮，其合成，活性和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1600127A (en) * | 1977-03-23 | 1981-10-14 | Wellcome Found | Piperazine-dione derivatives |
| EP0008186A1 (en) * | 1978-08-08 | 1980-02-20 | Beecham Group Plc | Cyclic diamides, a process for their preparation and their pharmaceutical compositions |
-
1984
- 1984-11-02 GB GB848427735A patent/GB8427735D0/en active Pending
-
1985
- 1985-10-29 CA CA000494059A patent/CA1257265A/en not_active Expired
- 1985-10-30 DK DK499385A patent/DK499385A/da not_active Application Discontinuation
- 1985-10-30 EP EP85307869A patent/EP0181152B1/en not_active Expired
- 1985-10-30 DE DE8585307869T patent/DE3572978D1/de not_active Expired
- 1985-10-30 AT AT85307869T patent/ATE46335T1/de not_active IP Right Cessation
- 1985-10-31 ES ES548418A patent/ES8702903A1/es not_active Expired
- 1985-11-02 KR KR1019850008160A patent/KR860004032A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE46335T1 (de) | 1989-09-15 |
| GB8427735D0 (en) | 1984-12-12 |
| EP0181152B1 (en) | 1989-09-13 |
| ES8702903A1 (es) | 1987-01-16 |
| ES548418A0 (es) | 1987-01-16 |
| CA1257265A (en) | 1989-07-11 |
| EP0181152A1 (en) | 1986-05-14 |
| DK499385A (da) | 1986-05-03 |
| KR860004032A (ko) | 1986-06-16 |
| DE3572978D1 (en) | 1989-10-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |