DK479688A - Substituerede 3-aminosydnoniminer og farmakologisk acceptable syreadditionssalte deraf, deres fremstilling og anvendelse - Google Patents

Substituerede 3-aminosydnoniminer og farmakologisk acceptable syreadditionssalte deraf, deres fremstilling og anvendelse

Info

Publication number
DK479688A
DK479688A DK479688A DK479688A DK479688A DK 479688 A DK479688 A DK 479688A DK 479688 A DK479688 A DK 479688A DK 479688 A DK479688 A DK 479688A DK 479688 A DK479688 A DK 479688A
Authority
DK
Denmark
Prior art keywords
substituted
acid addition
addition salts
acceptable acid
sydnonimines
Prior art date
Application number
DK479688A
Other languages
English (en)
Other versions
DK479688D0 (da
Inventor
Karl Schoenafinger
Rudi Beyerle
Helmut Bohn
Melitta Just
Original Assignee
Cassella Farbwerke Mainkur Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cassella Farbwerke Mainkur Ag filed Critical Cassella Farbwerke Mainkur Ag
Publication of DK479688D0 publication Critical patent/DK479688D0/da
Publication of DK479688A publication Critical patent/DK479688A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D271/00Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/041,2,3-Oxadiazoles; Hydrogenated 1,2,3-oxadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Detergent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK479688A 1987-09-24 1988-08-26 Substituerede 3-aminosydnoniminer og farmakologisk acceptable syreadditionssalte deraf, deres fremstilling og anvendelse DK479688A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873732174 DE3732174A1 (de) 1987-09-24 1987-09-24 Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
DK479688D0 DK479688D0 (da) 1988-08-26
DK479688A true DK479688A (da) 1989-03-25

Family

ID=6336771

Family Applications (1)

Application Number Title Priority Date Filing Date
DK479688A DK479688A (da) 1987-09-24 1988-08-26 Substituerede 3-aminosydnoniminer og farmakologisk acceptable syreadditionssalte deraf, deres fremstilling og anvendelse

Country Status (12)

Country Link
US (1) US4937244A (da)
EP (1) EP0312773B1 (da)
JP (1) JPH01106881A (da)
KR (1) KR890005094A (da)
AT (1) ATE70838T1 (da)
DE (2) DE3732174A1 (da)
DK (1) DK479688A (da)
ES (1) ES2037783T3 (da)
HU (1) HU203749B (da)
IL (1) IL87796A0 (da)
PT (1) PT88569B (da)
ZA (1) ZA887086B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221680A (en) * 1988-01-14 1993-06-22 Cassella Aktiengesellschaft Substituted 3-aminosydnonimines
DE4015236A1 (de) * 1990-05-13 1991-11-14 Cassella Ag Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE3921460A1 (de) * 1989-06-30 1991-01-03 Cassella Ag Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DE3921796A1 (de) * 1989-07-03 1991-01-17 Cassella Ag Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung
DK0429751T3 (da) * 1989-11-30 1993-12-13 Cassella Farbwerke Mainkur Ag Substituerede 3-aminosydnoniminer, fremgangsmåde til deres fremstilling og deres anvendelse
DE4031373A1 (de) * 1990-10-04 1992-04-09 Cassella Ag 3-piperazino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1695897C3 (de) * 1966-07-04 1979-02-15 Takeda Chemical Industries Ltd N-Acyl-sydnonimine, deren Salze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US3833580A (en) * 1966-08-09 1974-09-03 Boehringer Sohn Ingelheim 3-morpholino-n6-cyclohexylcarbonyl sydnonimine
CH507276A (de) * 1966-09-29 1971-05-15 Takeda Chemical Industries Ltd Verfahren zur Herstellung von Sydnoniminderivaten
US3833589A (en) * 1972-07-31 1974-09-03 Sandoz Ag Substituted sydnonimine nitrate esters
US4245100A (en) * 1977-11-28 1981-01-13 Vsesojuzny Nauchno-Issledovatelsky Khimikofarmatsevtichesky Institut Imeni S. Ordzhonikidze Sydnonimine N-acyl derivatives and method for preparing same
DE2930736A1 (de) * 1979-07-28 1981-02-12 Cassella Ag Pharmakologisch wirksame, substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
US4277609A (en) * 1979-08-31 1981-07-07 American Home Products Corporation Sydnone imines
US4446322A (en) * 1980-07-29 1984-05-01 American Home Products Corporation Hydroxyl protected 3-(2-hydroxy-2-phenylethyl)-N-[(phenylamino)carbonyl]sydnone imine intermediates
US4324897A (en) * 1980-10-02 1982-04-13 American Home Products Corporation 1,2,3 Oxadiazolium salts
US4289885A (en) * 1980-10-02 1981-09-15 American Home Products Corporation 3-[2-(Dimethylamino)-2-phenylethyl]N-[phenylamino)carbonyl]sydnone imine, a new central nervous system stimulant
US4301285A (en) * 1980-10-02 1981-11-17 American Home Products Corporation Sydnonimine CNS stimulants
US4371697A (en) * 1980-10-06 1983-02-01 American Home Products Corporation 3-[1-(Hydroxymethyl)-2-phenylethyl]-N-[(phenylamino)-carbonyl]sydnone imine
DE3107933A1 (de) * 1981-03-02 1982-09-16 Cassella Ag, 6000 Frankfurt Substituierte 3-amino-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung
US4371539A (en) * 1981-04-27 1983-02-01 American Home Products Corporation CNS Stimulants
JPS5832870A (ja) * 1981-08-24 1983-02-25 Hiroyoshi Hidaka 新規なシドノンイミン誘導体及びその製法
JPS5859977A (ja) * 1981-10-06 1983-04-09 Banyu Pharmaceut Co Ltd 新規なn−アシルシドノンイミン誘導体およびその製法

Also Published As

Publication number Publication date
DE3867205D1 (de) 1992-02-06
EP0312773B1 (de) 1991-12-27
ZA887086B (en) 1989-06-28
ATE70838T1 (de) 1992-01-15
JPH01106881A (ja) 1989-04-24
US4937244A (en) 1990-06-26
KR890005094A (ko) 1989-05-11
EP0312773A2 (de) 1989-04-26
DK479688D0 (da) 1988-08-26
PT88569B (pt) 1992-11-30
HUT51618A (en) 1990-05-28
HU203749B (en) 1991-09-30
ES2037783T3 (es) 1993-07-01
EP0312773A3 (en) 1990-05-09
DE3732174A1 (de) 1989-04-06
IL87796A0 (en) 1989-03-31
PT88569A (pt) 1988-10-01

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment