DK4074367T3 - Arrays til levering af tumorbehandlingsfelter (tt-felter) med individuelt tilgængelige elektrodeelementer og temperatursensorer - Google Patents
Arrays til levering af tumorbehandlingsfelter (tt-felter) med individuelt tilgængelige elektrodeelementer og temperatursensorer Download PDFInfo
- Publication number
- DK4074367T3 DK4074367T3 DK22177344.3T DK22177344T DK4074367T3 DK 4074367 T3 DK4074367 T3 DK 4074367T3 DK 22177344 T DK22177344 T DK 22177344T DK 4074367 T3 DK4074367 T3 DK 4074367T3
- Authority
- DK
- Denmark
- Prior art keywords
- fields
- arrays
- delivery
- temperature sensors
- electrode elements
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/3603—Control systems
- A61N1/36031—Control systems using physiological parameters for adjustment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
- A61N1/403—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00059—Material properties
- A61B2018/00071—Electrical conductivity
- A61B2018/00077—Electrical conductivity high, i.e. electrically conducting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/0016—Energy applicators arranged in a two- or three dimensional array
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00172—Connectors and adapters therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00666—Sensing and controlling the application of energy using a threshold value
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
- A61B2018/00815—Temperature measured by a thermistor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/0091—Handpieces of the surgical instrument or device
- A61B2018/00916—Handpieces of the surgical instrument or device with means for switching or controlling the main function of the instrument or device
- A61B2018/00922—Handpieces of the surgical instrument or device with means for switching or controlling the main function of the instrument or device by switching or controlling the treatment energy directly within the hand-piece
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0492—Patch electrodes
- A61N1/0496—Patch electrodes characterised by using specific chemical compositions, e.g. hydrogel compositions, adhesives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Physiology (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Plasma & Fusion (AREA)
- Otolaryngology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962955664P | 2019-12-31 | 2019-12-31 | |
EP20829225.0A EP4054701A1 (en) | 2019-12-31 | 2020-12-21 | Arrays for delivering tumor treating fields (ttfields) with individually accessible electrode elements and temperature sensors |
Publications (1)
Publication Number | Publication Date |
---|---|
DK4074367T3 true DK4074367T3 (da) | 2023-05-22 |
Family
ID=74004134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK22177344.3T DK4074367T3 (da) | 2019-12-31 | 2020-12-21 | Arrays til levering af tumorbehandlingsfelter (tt-felter) med individuelt tilgængelige elektrodeelementer og temperatursensorer |
Country Status (17)
Country | Link |
---|---|
US (2) | US11878163B2 (da) |
EP (3) | EP4054701A1 (da) |
JP (1) | JP2023508585A (da) |
KR (1) | KR20220123079A (da) |
CN (1) | CN114901344A (da) |
AU (1) | AU2020416669A1 (da) |
BR (1) | BR112022012409A2 (da) |
CA (1) | CA3163316A1 (da) |
DK (1) | DK4074367T3 (da) |
ES (1) | ES2950234T3 (da) |
FI (1) | FI4074367T3 (da) |
HU (1) | HUE061733T2 (da) |
IL (1) | IL294386A (da) |
MX (1) | MX2022006136A (da) |
PL (1) | PL4074367T3 (da) |
TW (1) | TW202138023A (da) |
WO (1) | WO2021137094A1 (da) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4147747A1 (en) | 2016-06-30 | 2023-03-15 | Novocure GmbH | Arrays for longitudinal delivery of ttfields to a body |
US11986647B2 (en) | 2018-09-07 | 2024-05-21 | Novocure Gmbh | Treating autoinflammatory and mitochondrial diseases using an alternating electric field |
EP3878505B1 (en) | 2018-10-15 | 2023-05-24 | Novocure GmbH | Generating tumor treating fields (ttfields) with high uniformity throughout the brain |
EP4019081B1 (en) | 2018-11-29 | 2024-04-03 | Novocure GmbH | Enhanced-flexibility transducer arrays for delivering ttfields (tumor treating fields) |
JP7246486B2 (ja) | 2019-01-08 | 2023-03-27 | ノボキュア ゲーエムベーハー | 腫瘍治療電場(ttfields)を使用した治療を計画するための異なるタイプの組織への画像のセグメンテーションの品質評価 |
PL3960232T3 (pl) | 2019-04-17 | 2023-05-15 | Novocure Gmbh | Załadowanie danych z układu izolowanego bez naruszania izolacji |
US11759628B2 (en) * | 2020-12-09 | 2023-09-19 | Lifebridge Innovations, Pbc | Insulated electrode for delivering tumor treating electromagnetic fields |
JP2024506311A (ja) * | 2021-02-17 | 2024-02-13 | ノボキュア ゲーエムベーハー | 個別に調節可能な活性領域を有する電極素子のセットで腫瘍治療電場(TTFields)を送達するためのアレイ |
WO2023042080A1 (en) * | 2021-09-14 | 2023-03-23 | Novocure Gmbh | Temperature independent method and system for applying ttfields |
WO2023116670A1 (zh) * | 2021-12-22 | 2023-06-29 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗***及其交流电信号施加方法 |
CN114534091B (zh) * | 2022-02-17 | 2022-09-09 | 湖南安泰康成生物科技有限公司 | 利用电场抑制肿瘤增殖的设备及其控制装置 |
US20240123228A1 (en) * | 2022-09-30 | 2024-04-18 | Novocure Gmbh | Single wire temperature measurement solution for a ttfield application system and methods of production and use thereof |
WO2024090939A1 (ko) * | 2022-10-25 | 2024-05-02 | 주식회사 필드큐어 | 전기장 전달 시스템 및 방법 |
CN115845260B (zh) * | 2022-12-30 | 2024-07-05 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗***及其电极片、温度检测方法 |
CN115980490B (zh) * | 2022-12-30 | 2024-04-19 | 江苏海莱新创医疗科技有限公司 | 电极片的质量检测***及方法、转接器、电场发生器 |
CN117839069A (zh) * | 2022-12-30 | 2024-04-09 | 江苏海莱新创医疗科技有限公司 | 肿瘤电场治疗***、肿瘤治疗设备及电极片温度检测方法 |
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US7805201B2 (en) | 2000-02-17 | 2010-09-28 | Standen Ltd. | Treating a tumor or the like with an electric field |
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US8447395B2 (en) | 2000-02-17 | 2013-05-21 | Novocure Ltd | Treating bacteria with electric fields |
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US8175698B2 (en) | 2000-02-17 | 2012-05-08 | Novocure Ltd. | Treating bacteria with electric fields |
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US9655669B2 (en) | 2013-05-06 | 2017-05-23 | Novocure Limited | Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment |
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US10945786B2 (en) * | 2013-10-18 | 2021-03-16 | Boston Scientific Scimed, Inc. | Balloon catheters with flexible conducting wires and related methods of use and manufacture |
US20190117963A1 (en) | 2014-07-25 | 2019-04-25 | Loyalty Based Innovations, LLC | Apparatus and method for treating multiple tumors in patients with metastatic disease by electric fields |
US9910453B2 (en) | 2015-09-25 | 2018-03-06 | Novocure Limited | High voltage, high efficiency sine wave generator with pre-set frequency and adjustable amplitude |
US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
US10821283B2 (en) | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
EP4147747A1 (en) | 2016-06-30 | 2023-03-15 | Novocure GmbH | Arrays for longitudinal delivery of ttfields to a body |
US20180008708A1 (en) | 2016-07-10 | 2018-01-11 | Novocure Limited | Synchronizing Tumor Cells to the G2/M Phase Using TTFields Combined with Taxane or Other Anti-Microtubule Agents |
WO2018033842A1 (en) * | 2016-08-18 | 2018-02-22 | Yoram Wasserman | Temperature measurement in arrays for delivering ttfields |
EP3974024A1 (en) | 2016-12-13 | 2022-03-30 | Novocure GmbH | Treating patients with ttfields with the electrode positions optimized using deformable templates |
CN110178029B (zh) | 2017-01-19 | 2021-11-16 | 诺沃库勒有限责任公司 | 用于在施加TTFields的同时在显微镜下观察细胞培养物的*** |
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US10953209B2 (en) | 2018-03-28 | 2021-03-23 | Board Of Regents Of The University Of Texas System | Treating tumors using TTFields combined with a PARP inhibitor |
JP7139448B2 (ja) | 2018-04-09 | 2022-09-20 | ノボキュア ゲーエムベーハー | TTFields及びオーロラキナーゼ阻害剤による腫瘍の治療 |
EP3832335A1 (en) | 2018-04-10 | 2021-06-09 | Zeev Bomzon | Low frequency (< 1 mhz) ac conductivity estimates derived from two mri images having different repetition times |
DK3838333T3 (da) | 2018-07-03 | 2023-03-27 | Univ Leland Stanford Junior | Anvendelse af elektriske vekselfelter til forøgelse af cellmembranpermeabilitet |
US11179322B2 (en) | 2018-07-10 | 2021-11-23 | Novocure Gmbh | Methods and compositions for treating tumors with TTFields and sorafenib |
AU2019301956B2 (en) | 2018-07-10 | 2023-04-13 | Novocure Gmbh | Inhibiting viral infection using alternating electric fields |
KR102607603B1 (ko) | 2018-07-18 | 2023-11-29 | 노보큐어 게엠베하 | 종양 치료장의 용량을 정량화하기 위한 전력 손실 밀도 및 관련 측정값의 사용 |
KR20240042240A (ko) | 2018-08-23 | 2024-04-01 | 카스텐 하게만 | 뇌-혈액 장벽 투과성을 향상시키기 위한 교번 전기장의 이용 |
US11160977B2 (en) | 2018-09-04 | 2021-11-02 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the infratentorial brain |
EP3846894A1 (en) | 2018-09-07 | 2021-07-14 | Novocure GmbH | Treating autoimmune diseases using an alternating electric field to reduce the proliferation of t-cells |
US20200108031A1 (en) | 2018-10-05 | 2020-04-09 | Novocure Gmbh | Treating Tumors Using TTFields Combined with ABT-751 |
EP3878505B1 (en) | 2018-10-15 | 2023-05-24 | Novocure GmbH | Generating tumor treating fields (ttfields) with high uniformity throughout the brain |
JP7282411B2 (ja) | 2018-10-23 | 2023-05-29 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 交流電場を使用する、幹細胞に基づく療法におけるテラトーマ形成の予防及び処置 |
CN112955208A (zh) | 2018-10-25 | 2021-06-11 | 吉夫·波姆桑 | 向受试者的脊柱解剖结构递送交变电场(例如,ttfields) |
US20200146586A1 (en) | 2018-11-14 | 2020-05-14 | Novocure Gmbh | Creating Accurate Computational Head Models of Patients Using Datasets Combining MRI and CT Images |
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JP7451511B2 (ja) | 2018-11-19 | 2024-03-18 | ノボキュア ゲーエムベーハー | 選択的にアドレス指定可能なサブ要素を有する腫瘍治療電場(ttfields)を提供するためのアレイ |
EP4019081B1 (en) | 2018-11-29 | 2024-04-03 | Novocure GmbH | Enhanced-flexibility transducer arrays for delivering ttfields (tumor treating fields) |
JP7246486B2 (ja) | 2019-01-08 | 2023-03-27 | ノボキュア ゲーエムベーハー | 腫瘍治療電場(ttfields)を使用した治療を計画するための異なるタイプの組織への画像のセグメンテーションの品質評価 |
KR20210130765A (ko) | 2019-02-22 | 2021-11-01 | 노보큐어 게엠베하 | Xelox, folfox 또는 이들의 각 구성 요소와 ttfield를 조합한 위암 치료 |
KR20240013279A (ko) | 2019-02-26 | 2024-01-30 | 노보큐어 게엠베하 | 표적 암세포들의 전기적 특징에 기초한 종양처리장 요법의 주파수 결정 |
EP3954314A1 (en) | 2019-02-27 | 2022-02-16 | Novocure GmbH | Delivering tumor treating fields (ttfields) using implantable transducer arrays |
EP3988099B1 (en) | 2019-03-29 | 2023-06-07 | Novocure GmbH | Methods for restoring sensitivity to ttfields in ttfields-resistant cancer cells with ptger3 inhibitors |
PL3960232T3 (pl) | 2019-04-17 | 2023-05-15 | Novocure Gmbh | Załadowanie danych z układu izolowanego bez naruszania izolacji |
EP4003492A1 (en) | 2019-07-31 | 2022-06-01 | Novocure GmbH | Applying tumor treating fields (ttfields) via electrodes embedded into skull implants |
JP2022545344A (ja) | 2019-08-05 | 2022-10-27 | ノボキュア ゲーエムベーハー | Il11活性を阻害することによって、腫瘍治療電場(ttフィールド)に対するがん細胞の感受性を高める |
US11890467B2 (en) | 2019-08-30 | 2024-02-06 | Novocure Gmbh | Delivering tumor treating fields (TTFields) to the neck |
WO2021050093A1 (en) | 2019-09-10 | 2021-03-18 | Novocure Gmbh | A method of reducing viability of cancer cells by applying alternating electric fields and administering checkpoint inhibitors to the cancer cells |
-
2020
- 2020-12-21 DK DK22177344.3T patent/DK4074367T3/da active
- 2020-12-21 EP EP20829225.0A patent/EP4054701A1/en active Pending
- 2020-12-21 EP EP22177344.3A patent/EP4074367B1/en active Active
- 2020-12-21 MX MX2022006136A patent/MX2022006136A/es unknown
- 2020-12-21 KR KR1020227026417A patent/KR20220123079A/ko unknown
- 2020-12-21 ES ES22177344T patent/ES2950234T3/es active Active
- 2020-12-21 JP JP2022540519A patent/JP2023508585A/ja active Pending
- 2020-12-21 HU HUE22177344A patent/HUE061733T2/hu unknown
- 2020-12-21 FI FIEP22177344.3T patent/FI4074367T3/fi active
- 2020-12-21 AU AU2020416669A patent/AU2020416669A1/en active Pending
- 2020-12-21 WO PCT/IB2020/062309 patent/WO2021137094A1/en unknown
- 2020-12-21 US US17/129,088 patent/US11878163B2/en active Active
- 2020-12-21 EP EP23161354.8A patent/EP4212203A1/en active Pending
- 2020-12-21 CN CN202080091024.6A patent/CN114901344A/zh active Pending
- 2020-12-21 IL IL294386A patent/IL294386A/en unknown
- 2020-12-21 BR BR112022012409A patent/BR112022012409A2/pt unknown
- 2020-12-21 PL PL22177344.3T patent/PL4074367T3/pl unknown
- 2020-12-21 CA CA3163316A patent/CA3163316A1/en active Pending
- 2020-12-25 TW TW109146226A patent/TW202138023A/zh unknown
-
2023
- 2023-12-14 US US18/540,012 patent/US20240139505A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
PL4074367T3 (pl) | 2023-07-31 |
FI4074367T3 (fi) | 2023-06-21 |
US20240139505A1 (en) | 2024-05-02 |
EP4212203A1 (en) | 2023-07-19 |
CN114901344A (zh) | 2022-08-12 |
US20210196348A1 (en) | 2021-07-01 |
KR20220123079A (ko) | 2022-09-05 |
EP4074367A1 (en) | 2022-10-19 |
BR112022012409A2 (pt) | 2022-08-30 |
CA3163316A1 (en) | 2021-07-08 |
MX2022006136A (es) | 2022-06-17 |
EP4074367B1 (en) | 2023-04-19 |
WO2021137094A1 (en) | 2021-07-08 |
TW202138023A (zh) | 2021-10-16 |
EP4054701A1 (en) | 2022-09-14 |
AU2020416669A1 (en) | 2022-06-16 |
ES2950234T3 (es) | 2023-10-06 |
HUE061733T2 (hu) | 2023-08-28 |
IL294386A (en) | 2022-08-01 |
US11878163B2 (en) | 2024-01-23 |
JP2023508585A (ja) | 2023-03-02 |
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