DK3996688T3 - Farmaceutisk præparat - Google Patents

Farmaceutisk præparat Download PDF

Info

Publication number
DK3996688T3
DK3996688T3 DK20736349.0T DK20736349T DK3996688T3 DK 3996688 T3 DK3996688 T3 DK 3996688T3 DK 20736349 T DK20736349 T DK 20736349T DK 3996688 T3 DK3996688 T3 DK 3996688T3
Authority
DK
Denmark
Prior art keywords
pharmaceutical preparation
pharmaceutical
preparation
Prior art date
Application number
DK20736349.0T
Other languages
English (en)
Inventor
Corinna Schoch
Markus Riehl
Gero Hooff
Markus Klemm
Carsten Schmidt
Markus Weigandt
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of DK3996688T3 publication Critical patent/DK3996688T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/485Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK20736349.0T 2019-07-10 2020-07-08 Farmaceutisk præparat DK3996688T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19185500 2019-07-10
PCT/EP2020/069165 WO2021005077A1 (en) 2019-07-10 2020-07-08 Pharmaceutical preparation

Publications (1)

Publication Number Publication Date
DK3996688T3 true DK3996688T3 (da) 2023-11-27

Family

ID=67226151

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20736349.0T DK3996688T3 (da) 2019-07-10 2020-07-08 Farmaceutisk præparat

Country Status (21)

Country Link
US (1) US20220288068A1 (da)
EP (2) EP4260910A3 (da)
JP (1) JP2022540170A (da)
KR (1) KR20220034183A (da)
CN (1) CN114025761A (da)
AU (1) AU2020309149A1 (da)
BR (1) BR112022000266A2 (da)
CA (1) CA3146384A1 (da)
DK (1) DK3996688T3 (da)
ES (1) ES2966788T3 (da)
FI (1) FI3996688T3 (da)
HR (1) HRP20231548T1 (da)
HU (1) HUE064434T2 (da)
IL (1) IL289481A (da)
LT (1) LT3996688T (da)
MX (1) MX2022000358A (da)
PL (1) PL3996688T3 (da)
PT (1) PT3996688T (da)
RS (1) RS64906B1 (da)
SI (1) SI3996688T1 (da)
WO (1) WO2021005077A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115919866A (zh) * 2022-12-07 2023-04-07 深圳海王医药科技研究院有限公司 特泊替尼固体分散体及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007032507A1 (de) 2007-07-12 2009-04-02 Merck Patent Gmbh Pyridazinonderivate
KR101829595B1 (ko) * 2009-01-08 2018-02-14 메르크 파텐트 게엠베하 3-(1-{3-[5-(1-메틸-피페리딘-4일메톡시)-피리미딘-2-일]-벤질}-6-옥소-1,6-디히드로-피리다진-3-일)-벤조니트릴 히드로클로라이드 염의 신규한 다형체 및 이의 제조 방법
DE102010035744A1 (de) 2010-08-28 2012-03-01 Merck Patent Gmbh Imidazolonylchinoline
RU2014141934A (ru) * 2012-03-19 2016-05-20 Мерк Патент Гмбх Комбинация производного 6-оксо-1,6-дигидро-пиридазина, которая обладает противораковым действием с другими противоопухолевыми соединениями
PT2914264T (pt) * 2012-11-02 2017-11-14 Merck Patent Gmbh Derivado 6-oxo-1,6-di-hidro-piridazina para utilização no tratamento de carcinoma hepatocelular (hcc)
AU2014377079A1 (en) * 2014-01-07 2016-08-18 Merck Patent Gmbh A 6-oxo-1,6-dihydro-pyridazine derivative for the use for the treatment of renal cell carcinoma (RCC)

Also Published As

Publication number Publication date
SI3996688T1 (sl) 2024-01-31
AU2020309149A1 (en) 2022-03-03
JP2022540170A (ja) 2022-09-14
EP4260910A2 (en) 2023-10-18
WO2021005077A1 (en) 2021-01-14
EP4260910A3 (en) 2023-12-27
FI3996688T3 (fi) 2023-11-30
RS64906B1 (sr) 2023-12-29
ES2966788T3 (es) 2024-04-24
EP3996688A1 (en) 2022-05-18
KR20220034183A (ko) 2022-03-17
LT3996688T (lt) 2023-12-27
EP3996688B1 (en) 2023-09-06
US20220288068A1 (en) 2022-09-15
CN114025761A (zh) 2022-02-08
PT3996688T (pt) 2023-11-29
HRP20231548T1 (hr) 2024-03-15
HUE064434T2 (hu) 2024-03-28
PL3996688T3 (pl) 2024-02-12
MX2022000358A (es) 2022-02-03
CA3146384A1 (en) 2021-01-14
IL289481A (en) 2022-02-01
BR112022000266A2 (pt) 2022-05-17

Similar Documents

Publication Publication Date Title
GB2569961B (en) Pharmaceutical
GB2572126B (en) Pharmaceutical
DK3529248T3 (da) Farmaceutiske sammensætninger
GB2572125B (en) Pharmaceutical
MA50541A (fr) Formulations pharmaceutiques
DK3935068T3 (da) Abirateron-prodrugs
DK3529240T3 (da) Farmaceutiske forbindelser
MA42303A (fr) Formulations pharmaceutiques
MA46867A (fr) Formulations pharmaceutiques
DK3634377T3 (da) Farmaceutisk formulering
MA49837A (fr) Compositions pharmaceutiques
DK3463345T3 (da) Farmaceutiske kombinationer
MA44987A (fr) Formulations de médicaments améliorées
MA47516A (fr) Composition pharmaceutique
MA55015A (fr) Formulations pharmaceutiques
DK3762009T3 (da) Toxin-afledte indgivelseskonstrukter til oral indgivelse
DK3256154T3 (da) Farmaceutisk formulering omfattende antistof
DK3280447T3 (da) Farmaceutiske formuleringer
DK3601277T3 (da) Farmaceutisk formulering
DK3886820T3 (da) Kapselformuleringer
DK3313370T3 (da) Oftalmologisk farmaceutisk sammensætning
DK3247394T3 (da) Farmaceutisk formulering omfattende anti-egfr-antistof
DK3996688T3 (da) Farmaceutisk præparat
DK3908321T3 (da) Farmaceutisk sammensætning
ZA202006346B (en) Pharmaceutical preparation