DK393489A - Benzodiazepinforbindelser og fremgangsmaade til deres fremstilling - Google Patents

Benzodiazepinforbindelser og fremgangsmaade til deres fremstilling Download PDF

Info

Publication number: DK393489A
Authority: DK; Denmark
Prior art keywords: benzodiazep; relations; procedures; preparation; benzodiazep relations
Prior art date: 1988-08-11

Application number

DK393489A

Other languages

English (en)

Other versions

DK393489D0 (da

Inventor

Jiban Kumar Chakrabarti

Terrence Michael Hotten

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-08-11

Filing date

1989-08-10

Publication date

1990-02-12

1989-08-10 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1989-08-10 Publication of DK393489D0 publication Critical patent/DK393489D0/da

1990-02-12 Publication of DK393489A publication Critical patent/DK393489A/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Thiazole And Isothizaole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)

DK393489A 1988-08-11 1989-08-10 Benzodiazepinforbindelser og fremgangsmaade til deres fremstilling DK393489A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888819059A GB8819059D0 (en)	1988-08-11	1988-08-11	Benzodiazepine compounds & their use as pharmaceuticals

Publications (2)

Publication Number	Publication Date
DK393489D0 DK393489D0 (da)	1989-08-10
DK393489A true DK393489A (da)	1990-02-12

Family

ID=10641942

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK393489A DK393489A (da)	1988-08-11	1989-08-10	Benzodiazepinforbindelser og fremgangsmaade til deres fremstilling

Country Status (22)

Country	Link
US (2)	US4977150A (da)
EP (1)	EP0354781B1 (da)
JP (1)	JP2779219B2 (da)
KR (1)	KR0138527B1 (da)
CN (1)	CN1025857C (da)
AR (1)	AR246972A1 (da)
AT (1)	ATE113600T1 (da)
AU (1)	AU625067B2 (da)
CA (1)	CA1318669C (da)
DE (1)	DE68919154T2 (da)
DK (1)	DK393489A (da)
ES (1)	ES2062012T3 (da)
GB (1)	GB8819059D0 (da)
HU (1)	HU202239B (da)
IE (1)	IE64598B1 (da)
IL (1)	IL91246A (da)
MX (1)	MX17107A (da)
NZ (1)	NZ230251A (da)
PH (1)	PH27010A (da)
PT (1)	PT91401B (da)
RU (1)	RU2002752C1 (da)
ZA (1)	ZA896039B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE1004596A4 (fr) *	1990-09-26	1992-12-22	Therabel Res S A N V	Derives de methylpiperazinoazepine, leur preparation et leur utilisation.
US5627178A (en)	1991-04-23	1997-05-06	Lilly Industries Limited	2-methyl-thieno-benzodiazepine
US5393752A (en) *	1992-05-26	1995-02-28	Therabel Research S.A./N.V.	Methylpiperazinoazepine compounds, preparation and use thereof
US6034078A (en) *	1992-05-29	2000-03-07	Eli Lilly And Company Limited	Thienobenzodiazepine compounds
US6617321B2 (en) *	1997-09-30	2003-09-09	Eli Lilly And Company	2-methyl-thieno-benzodiazepine formulation
ATE380818T1 (de) *	2002-03-28	2007-12-15	Lilly Co Eli	Piperazine-substituierte aryl-benzodiazepinen und ihre verwendung als dopaminrezeptor-antagonisten zur behandlung von psychose
DK1546134T3 (da) *	2002-08-05	2007-09-10	Lilly Co Eli	Piperazinsubstituerede arylbenzodiazepiner
EP1664063A1 (en) *	2003-09-09	2006-06-07	Eli Lilly And Company	Substituted piperazines of azepines, oxazepines, and thiazepines
ATE511512T1 (de) *	2005-01-05	2011-06-15	Lilly Co Eli	Olanzapinpamoat-dihydrat

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH468400A (de) *	1965-12-23	1969-02-15	Sandoz Ag	Verfahren zur Herstellung neuer Thieno(2,3-b)(1,5)benzothiazepin-4-on-Verbindungen
US3758479A (en) *	1967-03-22	1973-09-11	Sandoz Ag	Nitro and sulphamoyl substituted dibenzodiazepines
US3539573A (en) *	1967-03-22	1970-11-10	Jean Schmutz	11-basic substituted dibenzodiazepines and dibenzothiazepines
GB1292410A (en) *	1970-05-13	1972-10-11	Yoshitomi Pharmaceutical	Thienobenzothiazepine derivatives
CH554362A (de) *	1970-07-30	1974-09-30	Spofa Vereinigte Pharma Werke	Verfahren zur herstellung von neuen estern tricyklischer piperazinoalkanole.
US3897446A (en) *	1973-09-04	1975-07-29	Upjohn Co	6-Phenylthiazolo{8 3,2-a{9 {8 1,4{9 benzodiazepin-1-(2H)-ones, and processes
US4115568A (en) *	1974-11-26	1978-09-19	Lilly Industries Limited	Thieno[3,2-b]-[1,5]benzodiazepines
SU629879A3 (ru) *	1974-11-26	1978-10-25	Лилли Индастриз Лимитед, (Фирма)	Способ получени тиено(1,5) бензодиазепинов или их солей
US3951981A (en) *	1975-02-24	1976-04-20	American Cyanamid Company	Substituted benzodiazepines and method of use
US4404137A (en) *	1979-10-16	1983-09-13	Lilly Industries Limited	Pyrazolo [3,4-b][1,5]benzodiazepine compounds
US4431589A (en) *	1980-12-11	1984-02-14	Lilly House	Benzodiazepine compounds and their use as pharmaceuticals

1988
- 1988-08-11 GB GB888819059A patent/GB8819059D0/en active Pending
1989
- 1989-08-04 US US07/390,029 patent/US4977150A/en not_active Expired - Lifetime
- 1989-08-07 PH PH39061A patent/PH27010A/en unknown
- 1989-08-07 AU AU39399/89A patent/AU625067B2/en not_active Ceased
- 1989-08-08 ZA ZA896039A patent/ZA896039B/xx unknown
- 1989-08-08 IL IL9124689A patent/IL91246A/en not_active IP Right Cessation
- 1989-08-08 NZ NZ230251A patent/NZ230251A/en unknown
- 1989-08-08 MX MX1710789A patent/MX17107A/es unknown
- 1989-08-08 CA CA000607760A patent/CA1318669C/en not_active Expired - Fee Related
- 1989-08-08 PT PT91401A patent/PT91401B/pt active IP Right Grant
- 1989-08-09 ES ES89308099T patent/ES2062012T3/es not_active Expired - Lifetime
- 1989-08-09 AT AT89308099T patent/ATE113600T1/de not_active IP Right Cessation
- 1989-08-09 EP EP89308099A patent/EP0354781B1/en not_active Expired - Lifetime
- 1989-08-09 DE DE68919154T patent/DE68919154T2/de not_active Expired - Fee Related
- 1989-08-10 HU HU894101A patent/HU202239B/hu not_active IP Right Cessation
- 1989-08-10 CN CN89105557A patent/CN1025857C/zh not_active Expired - Fee Related
- 1989-08-10 IE IE257689A patent/IE64598B1/en not_active IP Right Cessation
- 1989-08-10 AR AR89314625A patent/AR246972A1/es active
- 1989-08-10 RU SU894614830A patent/RU2002752C1/ru active
- 1989-08-10 JP JP1207770A patent/JP2779219B2/ja not_active Expired - Lifetime
- 1989-08-10 KR KR1019890011365A patent/KR0138527B1/ko not_active IP Right Cessation
- 1989-08-10 DK DK393489A patent/DK393489A/da not_active Application Discontinuation
1990
- 1990-08-02 US US07/562,055 patent/US5051516A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES2062012T3 (es)	1994-12-16
JPH02104591A (ja)	1990-04-17
US4977150A (en)	1990-12-11
EP0354781B1 (en)	1994-11-02
NZ230251A (en)	1992-05-26
US5051516A (en)	1991-09-24
HU202239B (en)	1991-02-28
CN1040798A (zh)	1990-03-28
GB8819059D0 (en)	1988-09-14
EP0354781A3 (en)	1991-04-03
JP2779219B2 (ja)	1998-07-23
DK393489D0 (da)	1989-08-10
RU2002752C1 (ru)	1993-11-15
ZA896039B (en)	1991-04-24
IL91246A0 (en)	1990-03-19
IE892576L (en)	1990-02-11
PH27010A (en)	1993-02-01
AU625067B2 (en)	1992-07-02
IE64598B1 (en)	1995-08-23
CA1318669C (en)	1993-06-01
ATE113600T1 (de)	1994-11-15
PT91401B (pt)	1995-05-04
HUT53109A (en)	1990-09-28
PT91401A (pt)	1990-03-08
IL91246A (en)	1994-01-25
KR0138527B1 (ko)	1998-05-15
AU3939989A (en)	1990-02-15
KR900003179A (ko)	1990-03-23
MX17107A (es)	1993-08-01
CN1025857C (zh)	1994-09-07
DE68919154D1 (de)	1994-12-08
AR246972A1 (es)	1994-10-31
DE68919154T2 (de)	1995-03-09
EP0354781A2 (en)	1990-02-14

Legal Events

Date	Code	Title	Description
2003-08-11	AHS	Application shelved for other reasons than non-payment

Publication	Publication Date	Title
NO893678L (no)	1990-03-19	Cyklosporinholdige preparater og fremgangsmaate for deres fremstilling.
DK166084C (da)	1993-08-02	Imidazoquinolinyletherderivater og fremgangsmaade til deres fremstilling
DK374389A (da)	1990-01-30	Arylbenzenoxazolidinoner, deres fremstilling og anvendelse
DK242389D0 (da)	1989-05-18	Hydroxamatderivater og fremgangsmaade til fremstilling deraf
NO900577D0 (no)	1990-02-07	Cyklosporinholdige preparater og fremgangsmaate for deres fremstilling.
NO893196D0 (no)	1989-08-08	Hybrid-protein-c-sammensetninger og fremgangsmaater for deres fremstilling.
DK159288D0 (da)	1988-03-23	Saccharidblanding og fremgangsmaade til fremstilling deraf
DK631587D0 (da)	1987-12-01	Imidazolderivater og fremgangsmaade til deres fremstilling
NO894624D0 (no)	1989-11-21	Kopolymerer og fremgangsmaate for deres fremstilling.
DK388989D0 (da)	1989-08-08	Acylcyanoguanidiner, deres fremstilling og anvendelse
DK69989A (da)	1989-08-17	Benzodioxolderivater og fremgangsmaade til fremstilling deraf
DK435289A (da)	1990-03-04	Piperazindioner, deres fremstilling og anvendelse
DK1693A (da)	1993-01-07	Pyranobenzoxadiazolderivat og fremgangsmaade til fremstilling deraf
DK393489D0 (da)	1989-08-10	Benzodiazepinforbindelser og fremgangsmaade til deres fremstilling
NO883114D0 (no)	1988-07-12	1h-pyrazol-1-alkanamider og fremgangsmaate for deres fremstilling.
DK225089D0 (da)	1989-05-08	2-adamantyl-4-isothiazolin-3-oner, deres fremstilling og anvendelse
NO851687L (no)	1985-10-28	Kryssbundne karboksyl-polyelektrolytter og fremgangsmaate for deres fremstilling
DK634089D0 (da)	1989-12-14	Polyhydroxybenzyloxypropanolaminer og deres anvendelse
DK79389D0 (da)	1989-02-21	Thiorhodaminer samt fremgangsmaade og mellemprodukter til deres fremstilling
DK501989D0 (da)	1989-10-10	Mikrobiocidt praeparat og dettes fremstilling
NO893565L (no)	1990-03-07	Etansulfonamidderivater og fremgangsmaate for deres fremstilling.
NO894697L (no)	1990-05-28	Penemderivater og fremgangsmaater for deres fremstilling.
DK129689A (da)	1989-09-20	Ifosfamid-mesna-lyofilisat og fremgangsmaade til fremstilling deraf
DK180588A (da)	1988-10-03	Anti-tumor-virksomme praeparater og fremgangsmaade til deres fremstilling
NO922608D0 (no)	1992-07-01	Nye cefalosporinforbindelser og fremgangsmaater til deres fremstilling