DK3868741T3 - Sammensætning omfattende en pyrimidinforbindelse og et patogenafledt antigen - Google Patents

Sammensætning omfattende en pyrimidinforbindelse og et patogenafledt antigen Download PDF

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Publication number
DK3868741T3
DK3868741T3 DK21164640.1T DK21164640T DK3868741T3 DK 3868741 T3 DK3868741 T3 DK 3868741T3 DK 21164640 T DK21164640 T DK 21164640T DK 3868741 T3 DK3868741 T3 DK 3868741T3
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Prior art keywords
pyrimide
pathogen
compound
composition
derived antigen
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DK21164640.1T
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English (en)
Inventor
Hidenori Kimura
Hitoshi Ban
Yoshiaki Isobe
Hitoshi Watanabe
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Sumitomo Pharma Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Oncology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK21164640.1T 2015-10-07 2016-10-06 Sammensætning omfattende en pyrimidinforbindelse og et patogenafledt antigen DK3868741T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015199750 2015-10-07
EP16853686.0A EP3360864B1 (en) 2015-10-07 2016-10-06 Pyrimidine compound

Publications (1)

Publication Number Publication Date
DK3868741T3 true DK3868741T3 (da) 2023-11-06

Family

ID=58487860

Family Applications (2)

Application Number Title Priority Date Filing Date
DK21164640.1T DK3868741T3 (da) 2015-10-07 2016-10-06 Sammensætning omfattende en pyrimidinforbindelse og et patogenafledt antigen
DK16853686.0T DK3360864T3 (da) 2015-10-07 2016-10-06 Pyrimidinforbindelse

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK16853686.0T DK3360864T3 (da) 2015-10-07 2016-10-06 Pyrimidinforbindelse

Country Status (21)

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US (3) US10632192B2 (da)
EP (2) EP3868741B1 (da)
JP (3) JP6769976B2 (da)
KR (1) KR102651207B1 (da)
CN (1) CN108290845B (da)
AU (1) AU2016334826B2 (da)
CA (1) CA3001283C (da)
CY (1) CY1124542T1 (da)
DK (2) DK3868741T3 (da)
ES (2) ES2960724T3 (da)
FI (1) FI3868741T3 (da)
HK (1) HK1255921A1 (da)
HU (2) HUE064322T2 (da)
MY (1) MY194902A (da)
PH (1) PH12018500755A1 (da)
PL (2) PL3868741T3 (da)
PT (2) PT3360864T (da)
RU (1) RU2759917C2 (da)
SG (1) SG11201802832UA (da)
TW (1) TWI718188B (da)
WO (1) WO2017061532A1 (da)

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Also Published As

Publication number Publication date
EP3868741A1 (en) 2021-08-25
US20220226468A1 (en) 2022-07-21
DK3360864T3 (da) 2021-06-14
US20210008197A1 (en) 2021-01-14
SG11201802832UA (en) 2018-05-30
PT3868741T (pt) 2023-10-19
US20180280499A1 (en) 2018-10-04
US11266738B2 (en) 2022-03-08
TWI718188B (zh) 2021-02-11
ES2870679T3 (es) 2021-10-27
PL3360864T3 (pl) 2021-10-25
JPWO2017061532A1 (ja) 2018-08-02
CA3001283A1 (en) 2017-04-13
RU2018116351A3 (da) 2020-02-25
HUE064322T2 (hu) 2024-03-28
RU2018116351A (ru) 2019-11-07
JP6769976B2 (ja) 2020-10-14
WO2017061532A1 (ja) 2017-04-13
EP3360864A4 (en) 2019-05-29
US10632192B2 (en) 2020-04-28
AU2016334826B2 (en) 2020-08-27
MY194902A (en) 2022-12-22
CN108290845B (zh) 2021-08-03
RU2759917C2 (ru) 2021-11-18
EP3360864B1 (en) 2021-04-28
JP7195398B2 (ja) 2022-12-23
FI3868741T3 (fi) 2023-10-02
AU2016334826A1 (en) 2018-05-10
JP2022010266A (ja) 2022-01-14
JP2021001210A (ja) 2021-01-07
KR102651207B1 (ko) 2024-03-25
CY1124542T1 (el) 2022-07-22
PH12018500755A1 (en) 2018-10-15
EP3868741B1 (en) 2023-08-30
US11911466B2 (en) 2024-02-27
TW201718518A (zh) 2017-06-01
HK1255921A1 (zh) 2019-09-06
PL3868741T3 (pl) 2024-01-29
CN108290845A (zh) 2018-07-17
CA3001283C (en) 2023-10-10
HUE055079T2 (hu) 2021-10-28
ES2960724T3 (es) 2024-03-06
KR20180056774A (ko) 2018-05-29
EP3360864A1 (en) 2018-08-15
PT3360864T (pt) 2021-06-02

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