DK372089A - Anvendelse af isoquinolinderivater - Google Patents

Anvendelse af isoquinolinderivater Download PDF

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Publication number
DK372089A
DK372089A DK372089A DK372089A DK372089A DK 372089 A DK372089 A DK 372089A DK 372089 A DK372089 A DK 372089A DK 372089 A DK372089 A DK 372089A DK 372089 A DK372089 A DK 372089A
Authority
DK
Denmark
Prior art keywords
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Application number
DK372089A
Other languages
Danish (da)
English (en)
Other versions
DK372089D0 (da
Inventor
William Joseph Houlihan
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK372089D0 publication Critical patent/DK372089D0/da
Publication of DK372089A publication Critical patent/DK372089A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
DK372089A 1988-07-29 1989-07-27 Anvendelse af isoquinolinderivater DK372089A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22630588A 1988-07-29 1988-07-29
US07/302,720 US4910206A (en) 1986-07-14 1989-01-27 5-hetero-or aryl-substituted-imidazo(2,1-a)isoquinolines and their use as PAF receptor antagonists

Publications (2)

Publication Number Publication Date
DK372089D0 DK372089D0 (da) 1989-07-27
DK372089A true DK372089A (da) 1990-01-30

Family

ID=26920416

Family Applications (1)

Application Number Title Priority Date Filing Date
DK372089A DK372089A (da) 1988-07-29 1989-07-27 Anvendelse af isoquinolinderivater

Country Status (16)

Country Link
US (1) US4910206A (es)
EP (1) EP0357550B1 (es)
JP (1) JPH0273016A (es)
KR (1) KR910002445A (es)
AU (1) AU632487B2 (es)
CA (1) CA1336503C (es)
DE (1) DE68913397T2 (es)
DK (1) DK372089A (es)
ES (1) ES2062092T3 (es)
FI (1) FI893616A (es)
HU (1) HU206040B (es)
IE (1) IE63243B1 (es)
IL (1) IL91128A (es)
NO (1) NO177485C (es)
NZ (1) NZ230098A (es)
PT (1) PT91302B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0345931B1 (en) * 1988-04-27 1993-01-20 Schering Corporation Certain paf antagonist/antihistamine combinations and methods
US5639782A (en) * 1992-03-04 1997-06-17 Center For Innovative Technology Neolignan derivatives as platelet activating factor receptor antagonists and 5-lipoxygenase inhibitors
US5530141A (en) * 1992-03-04 1996-06-25 Center For Innovative Technology 2,4-diaryl-1,3-dithiolanes; 2,4-diaryl-1,3-dioxolanes; 2,4-diaryl-1,3-oxathiolanes; and 2,5-diaryl-1,3-oxathiolanes for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5463083A (en) * 1992-07-13 1995-10-31 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
PT650485E (pt) 1992-07-13 2001-03-30 Millennium Pharm Inc 2,5-diaril-tetra-hidro-tiofenos -furanos e analogos para o tratamento de desordens inflamatorias e imunitarias
US5358938A (en) * 1992-07-13 1994-10-25 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5434151A (en) * 1992-08-24 1995-07-18 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5648486A (en) * 1992-07-13 1997-07-15 Cytomed, Inc. Compounds and methods for the treatment of inflammatory and immune disorders
US5703093A (en) * 1995-05-31 1997-12-30 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5750565A (en) 1995-05-25 1998-05-12 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5792776A (en) * 1994-06-27 1998-08-11 Cytomed, Inc., Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
FR2756560A1 (fr) * 1996-12-04 1998-06-05 Adir Nouveaux derives de l'imidazoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN1076728C (zh) * 1999-02-05 2001-12-26 浙江大学 2-芳基咪唑并[2,1-a]异喹啉的衍生物及其用途
WO2021057696A1 (zh) * 2019-09-27 2021-04-01 隆泰申医药科技(南京)有限公司 一种杂芳基类化合物及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4101553A (en) * 1974-01-02 1978-07-18 Sandoz, Inc. Imidazo[2,1-a]isoquinolines
HU172649B (hu) * 1975-04-24 1978-11-28 Gyogyszerkutato Intezet Sposob poluchenija novykh biologicheski aktivnykh lizergamidov
ATE74357T1 (de) * 1986-07-14 1992-04-15 Sandoz Ag 5-hetero- oder -aryl-substituierte imidazo(2,1a>isochinoline.

Also Published As

Publication number Publication date
EP0357550B1 (en) 1994-03-02
NO177485B (no) 1995-06-19
PT91302A (pt) 1990-02-08
EP0357550A2 (en) 1990-03-07
IE63243B1 (en) 1995-04-05
NZ230098A (en) 1992-02-25
NO177485C (no) 1995-09-27
NO893062L (no) 1990-01-30
FI893616A (fi) 1990-01-30
HU206040B (en) 1992-08-28
ES2062092T3 (es) 1994-12-16
FI893616A0 (fi) 1989-07-28
JPH0273016A (ja) 1990-03-13
CA1336503C (en) 1995-08-01
KR910002445A (ko) 1991-02-25
EP0357550A3 (en) 1991-04-03
PT91302B (pt) 1995-03-01
DE68913397D1 (de) 1994-04-07
AU632487B2 (en) 1993-01-07
DE68913397T2 (de) 1994-08-11
IL91128A (en) 1996-01-31
HUT50630A (en) 1990-03-28
NO893062D0 (no) 1989-07-27
IE892459L (en) 1990-01-29
AU3901789A (en) 1990-02-01
US4910206A (en) 1990-03-20
IL91128A0 (en) 1990-03-19
DK372089D0 (da) 1989-07-27

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment