DK3604525T3 - Fremgangsmåde til tilvejebringelse af et dna-indkodet bibliotek, dna-inkodet bibliotek og fremgangsmåde til at afkode et dna-indkodet bibliotek - Google Patents
Fremgangsmåde til tilvejebringelse af et dna-indkodet bibliotek, dna-inkodet bibliotek og fremgangsmåde til at afkode et dna-indkodet bibliotek Download PDFInfo
- Publication number
- DK3604525T3 DK3604525T3 DK18186948.8T DK18186948T DK3604525T3 DK 3604525 T3 DK3604525 T3 DK 3604525T3 DK 18186948 T DK18186948 T DK 18186948T DK 3604525 T3 DK3604525 T3 DK 3604525T3
- Authority
- DK
- Denmark
- Prior art keywords
- dna
- encoded library
- decoding
- providing
- library
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1089—Design, preparation, screening or analysis of libraries using computer algorithms
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
- C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/08—Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support
- C40B50/10—Liquid phase synthesis, i.e. wherein all library building blocks are in liquid phase or in solution during library creation; Particular methods of cleavage from the liquid support involving encoding steps
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Structural Engineering (AREA)
- Analytical Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP18186948.8A EP3604525B1 (en) | 2018-08-02 | 2018-08-02 | Method for providing a dna-encoded library, dna-encoded library and method of decoding a dna-encoded library |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3604525T3 true DK3604525T3 (da) | 2021-05-31 |
Family
ID=63293916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK18186948.8T DK3604525T3 (da) | 2018-08-02 | 2018-08-02 | Fremgangsmåde til tilvejebringelse af et dna-indkodet bibliotek, dna-inkodet bibliotek og fremgangsmåde til at afkode et dna-indkodet bibliotek |
Country Status (4)
Country | Link |
---|---|
US (1) | US20200040326A1 (da) |
EP (1) | EP3604525B1 (da) |
JP (1) | JP7397464B2 (da) |
DK (1) | DK3604525T3 (da) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113373524B (zh) * | 2020-05-11 | 2022-10-25 | 南京世和基因生物技术股份有限公司 | 一种ctDNA测序标签接头、文库、检测方法和试剂盒 |
CN114411267B (zh) * | 2020-10-28 | 2024-04-16 | 成都先导药物开发股份有限公司 | 一种On-DNA反应构建β-脂肪取代酮类化合物的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201218909D0 (en) * | 2012-10-22 | 2012-12-05 | Univ Singapore | Assay for the parallel detection of biological material based on PCR |
CA2889862C (en) | 2012-11-05 | 2021-02-16 | Rubicon Genomics, Inc. | Barcoding nucleic acids |
DE102014213783B3 (de) * | 2014-07-16 | 2015-06-18 | Technische Universität Dresden | Verfahren zur Identifizierung hochaffiner Komplexe aus zwei Liganden und einem Rezeptor, Vorrichtung zur Durchführung des Verfahrens und selbst-assemblierende chemische Bibliothek zur Verwendung in dem Verfahren |
US11996168B2 (en) * | 2015-10-28 | 2024-05-28 | The Broad Institute, Inc. | Systems and methods for determining relative abundances of biomolecules |
WO2018005720A1 (en) * | 2016-06-30 | 2018-01-04 | President And Fellows Of Harvard College | Method of determining the molecular binding between libraries of molecules |
EP3545106B1 (en) * | 2017-08-01 | 2022-01-19 | Helitec Limited | Methods of enriching and determining target nucleotide sequences |
-
2018
- 2018-08-02 DK DK18186948.8T patent/DK3604525T3/da active
- 2018-08-02 EP EP18186948.8A patent/EP3604525B1/en active Active
-
2019
- 2019-07-30 US US16/525,936 patent/US20200040326A1/en not_active Abandoned
- 2019-08-02 JP JP2019142687A patent/JP7397464B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
JP7397464B2 (ja) | 2023-12-13 |
US20200040326A1 (en) | 2020-02-06 |
JP2020054337A (ja) | 2020-04-09 |
EP3604525A1 (en) | 2020-02-05 |
EP3604525B1 (en) | 2021-03-10 |
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