DK3543337T3 - Hidtil ukendt fab-fragment af et anti-humant muc1-antistof - Google Patents

Hidtil ukendt fab-fragment af et anti-humant muc1-antistof Download PDF

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Publication number
DK3543337T3
DK3543337T3 DK17870672.7T DK17870672T DK3543337T3 DK 3543337 T3 DK3543337 T3 DK 3543337T3 DK 17870672 T DK17870672 T DK 17870672T DK 3543337 T3 DK3543337 T3 DK 3543337T3
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Prior art keywords
fab fragment
hitherto unknown
muc1 antibody
human muc1
human
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DK17870672.7T
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English (en)
Inventor
Akifumi Morinaka
Hiroki Shirai
Kazunori Hirayama
Naomi Hosogai
Hitoshi Doihara
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Astellas Pharma Inc
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Publication of DK3543337T3 publication Critical patent/DK3543337T3/da

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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4725—Mucins, e.g. human intestinal mucin

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