DK3487996T3 - Serinproteasevarianter og polynukleotider, der koder for samme - Google Patents

Serinproteasevarianter og polynukleotider, der koder for samme Download PDF

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Publication number
DK3487996T3
DK3487996T3 DK17746005.2T DK17746005T DK3487996T3 DK 3487996 T3 DK3487996 T3 DK 3487996T3 DK 17746005 T DK17746005 T DK 17746005T DK 3487996 T3 DK3487996 T3 DK 3487996T3
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DK
Denmark
Prior art keywords
polynucleotides encoding
serine protease
encoding same
protease variants
variants
Prior art date
Application number
DK17746005.2T
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English (en)
Inventor
Keiichi Ayabe
Tomoko Matsui
Aki Tomiki
Yuma Kurakata
Esben P Friis
Jens E Nielsen
Roland Alexander Pache
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Novozymes As
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Publication of DK3487996T3 publication Critical patent/DK3487996T3/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK17746005.2T 2016-07-21 2017-07-14 Serinproteasevarianter og polynukleotider, der koder for samme DK3487996T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16180497 2016-07-21
EP16195078 2016-10-21
PCT/EP2017/067883 WO2018015304A1 (en) 2016-07-21 2017-07-14 Serine protease variants and polynucleotides encoding same

Publications (1)

Publication Number Publication Date
DK3487996T3 true DK3487996T3 (da) 2024-05-21

Family

ID=59501396

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17746005.2T DK3487996T3 (da) 2016-07-21 2017-07-14 Serinproteasevarianter og polynukleotider, der koder for samme

Country Status (7)

Country Link
US (3) US10927361B2 (da)
EP (1) EP3487996B1 (da)
CN (1) CN109642225A (da)
CA (1) CA3028875A1 (da)
DK (1) DK3487996T3 (da)
MX (1) MX2019000805A (da)
WO (1) WO2018015304A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109642225A (zh) * 2016-07-21 2019-04-16 诺维信公司 丝氨酸蛋白酶变体以及对其进行编码的多核苷酸
US11891645B2 (en) 2016-07-21 2024-02-06 Novozymes A/S Serine protease variants and polynucleotides encoding same
EP3942033A1 (en) * 2019-03-18 2022-01-26 Novozymes A/S Polypeptides having pullulanase activity suitable for use in liquefaction
KR102316445B1 (ko) * 2019-11-29 2021-10-26 씨제이제일제당 주식회사 신규 세린 프로테아제 변이체
CN112574978B (zh) * 2021-01-19 2021-08-17 青岛尚德生物技术有限公司 提高降解醇溶蛋白能力的蛋白酶突变体及其编码基因和应用
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3912590A (en) 1973-01-03 1975-10-14 Novo Industri As Procedure for liquefying starch
US4316956A (en) 1980-02-06 1982-02-23 Novo Industri A/S Fermentation process
US4335208A (en) 1980-03-11 1982-06-15 Novo Industri A/S Saccharification of starch hydrolysates
JPS57174089A (en) 1981-04-20 1982-10-26 Novo Industri As Chain dividing enzyme product
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
ES2052565T3 (es) 1986-07-09 1994-07-16 Novo Nordisk As Un procedimiento para licuar una suspension de almidon o granos amilaceos.
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
JP3016587B2 (ja) 1989-12-04 2000-03-06 ザ・リサーチ・ファンデーション・オブ・ステート・ユニバーシティ・オブ・ニューヨーク 非ステロイド抗炎症剤及びテトラサイクリンの配合
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
US5231017A (en) 1991-05-17 1993-07-27 Solvay Enzymes, Inc. Process for producing ethanol
DE4343591A1 (de) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
WO1995033836A1 (en) 1994-06-03 1995-12-14 Novo Nordisk Biotech, Inc. Phosphonyldipeptides useful in the treatment of cardiovascular diseases
EP1559776A3 (en) 1994-06-30 2006-01-11 Novozymes Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic Fusarium expression system and promoters and terminators for use therein
EP1023439B1 (en) 1997-10-13 2009-02-18 Novozymes A/S alpha-AMYLASE MUTANTS
EP1124949B1 (en) 1998-10-26 2006-07-12 Novozymes A/S Constructing and screening a dna library of interest in filamentous fungal cells
JP4620253B2 (ja) 1999-03-22 2011-01-26 ノボザイムス，インコーポレイティド 菌類細胞中で遺伝子を発現させるためのプロモーター
JP2005500841A (ja) 2001-07-27 2005-01-13 アメリカ合衆国 オリゴヌクレオチドを用いるインビボ部位指定変異誘発のためのシステム
CN100448996C (zh) 2002-01-23 2009-01-07 皇家奈达尔科股份有限公司 戊糖的发酵
CA2475416A1 (en) 2002-02-08 2003-08-14 Genencor International, Inc. Methods for producing ethanol from carbon substrates
WO2004085627A1 (en) 2003-03-26 2004-10-07 Forskarpatent I Syd Ab New saccharomyces cerevisiae strains utilizing xylose
US7968318B2 (en) 2006-06-06 2011-06-28 Genencor International, Inc. Process for conversion of granular starch to ethanol
US8399215B2 (en) 2008-03-07 2013-03-19 Dsm Ip Assets B.V. Pentose sugar fermenting cell
EP2326723B1 (en) * 2008-08-20 2016-07-06 Novozymes A/S Processes for producing fermentation products
EP2367928B1 (en) 2008-12-24 2018-03-14 DSM IP Assets B.V. Xylose isomerase genes and their use in fermentation of pentose sugars
WO2011066576A1 (en) 2009-11-30 2011-06-03 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
AU2010276471B2 (en) 2009-12-01 2015-05-14 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
JP5874039B2 (ja) 2010-11-05 2016-03-01 パナソニックＩｐマネジメント株式会社 ステレオ画像処理装置及びステレオ画像処理方法
CN103298932B (zh) 2010-11-08 2016-08-10 诺维信公司 具有葡糖淀粉酶活性的多肽和编码该多肽的多核苷酸
EP2527448A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi
CA2840962C (en) 2011-07-06 2021-04-13 Novozymes A/S Alpha amylase variants and polynucleotides encoding same
EP2893012B1 (en) * 2012-09-05 2018-08-15 Novozymes A/S Polypeptides having protease activity
CN106455630B (zh) 2014-06-27 2021-08-24 帝斯曼知识产权资产管理有限公司 改进动物饲料的营养价值的方法
MX2018003449A (es) 2015-09-25 2018-06-06 Novozymes As Uso de serina proteasas para mejorar el rendimiento de etanol.
US11891645B2 (en) * 2016-07-21 2024-02-06 Novozymes A/S Serine protease variants and polynucleotides encoding same
CN109642225A (zh) * 2016-07-21 2019-04-16 诺维信公司 丝氨酸蛋白酶变体以及对其进行编码的多核苷酸

Also Published As

Publication number Publication date
US20190352629A1 (en) 2019-11-21
US10927361B2 (en) 2021-02-23
EP3487996B1 (en) 2024-04-10
CA3028875A1 (en) 2018-01-25
MX2019000805A (es) 2019-06-20
EP3487996A1 (en) 2019-05-29
WO2018015304A1 (en) 2018-01-25
US11447763B2 (en) 2022-09-20
US20210139876A1 (en) 2021-05-13
US20220090041A1 (en) 2022-03-24
CN109642225A (zh) 2019-04-16

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