DK3470414T3 - Benzodiazepinderivat med aktivitet på centralnerve- og karsystemerne - Google Patents

Benzodiazepinderivat med aktivitet på centralnerve- og karsystemerne Download PDF

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Publication number
DK3470414T3
DK3470414T3 DK17732729.3T DK17732729T DK3470414T3 DK 3470414 T3 DK3470414 T3 DK 3470414T3 DK 17732729 T DK17732729 T DK 17732729T DK 3470414 T3 DK3470414 T3 DK 3470414T3
Authority
DK
Denmark
Prior art keywords
activity
central nervous
vessel systems
benzodiazepin
derivative
Prior art date
Application number
DK17732729.3T
Other languages
English (en)
Inventor
Fonseca Luis Arturo Fonseca
Reyes Yamila Verdecia
Figueredo Yanier Núñez
Guerra Maylin Wong
Suárez Bárbara Beatriz Garrido
Andreu Gilberto Lázaro Pardo
Rodríguez Estael Ochoa
Fernández Pedro Gilberto Bárzaga
Alfonso Nicté González
Hernández René Delgado
Yaquis Alejandro Saúl Padrón
Sánchez Jeney Ramírez
Original Assignee
Univ La Habana
Centro De Investig Y Desarrollo De Medicamentos Cidem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ La Habana, Centro De Investig Y Desarrollo De Medicamentos Cidem filed Critical Univ La Habana
Application granted granted Critical
Publication of DK3470414T3 publication Critical patent/DK3470414T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK17732729.3T 2016-05-04 2017-05-03 Benzodiazepinderivat med aktivitet på centralnerve- og karsystemerne DK3470414T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CUP2016000058A CU20160058A7 (es) 2016-05-04 2016-05-04 Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascular
PCT/CU2017/050002 WO2017190713A1 (es) 2016-05-04 2017-05-03 Derivado de benzodiazepina con actividad sobre el sistema nervioso central y vascular

Publications (1)

Publication Number Publication Date
DK3470414T3 true DK3470414T3 (da) 2022-01-17

Family

ID=59215419

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17732729.3T DK3470414T3 (da) 2016-05-04 2017-05-03 Benzodiazepinderivat med aktivitet på centralnerve- og karsystemerne

Country Status (20)

Country Link
US (1) US11098039B2 (da)
EP (1) EP3470414B1 (da)
JP (1) JP7078959B2 (da)
KR (1) KR102428383B1 (da)
CN (1) CN110114356B (da)
AR (1) AR108369A1 (da)
AU (1) AU2017259748B2 (da)
BR (1) BR112018072588B1 (da)
CA (1) CA3023105C (da)
CL (1) CL2018003113A1 (da)
CU (1) CU20160058A7 (da)
DK (1) DK3470414T3 (da)
EA (1) EA201892461A1 (da)
ES (1) ES2902992T3 (da)
MX (1) MX2018013405A (da)
NZ (1) NZ748959A (da)
SG (1) SG11201809845TA (da)
SI (1) SI3470414T1 (da)
WO (1) WO2017190713A1 (da)
ZA (1) ZA201808162B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU20190114A7 (es) 2019-12-26 2021-08-06 Centro De Investig Y Desarrollo De Medicamentos Cidem Combinación para simultáneamente incrementar la eficacia analgésica de la morfina y reducir su dependencia física
BR112022012699A2 (pt) 2019-12-26 2022-09-06 Centro De Investig Y Desarrollo De Medicamentos Cidem Uso de um derivado de benzodiazepina e método de tratamento de lesão cerebral traumática

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110288070A1 (en) * 2008-05-05 2011-11-24 ROGERS Kathryn Methods for treating cognitive disorders using inhibitors of histone deacetylase
CU20090172A7 (es) * 2009-10-09 2011-10-05 Ct De Investigación Y Desarrollo De Medicamentos Sistemas tricíclicos y tetracíclicos con actividad sobre el sistema nervioso central y vascular
CU24576B1 (es) 2016-05-04 2022-02-04 Centro De Investig Y Desarrollo De Medicamentos Cidem Compuesto fenólico y combinación del mismo con una benzodiazepina fusionada a 1,4-dihidropiridina para el tratamiento de afecciones del sistema nervioso central y vascular

Also Published As

Publication number Publication date
CN110114356A (zh) 2019-08-09
CU20160058A7 (es) 2017-12-08
US20190270738A1 (en) 2019-09-05
BR112018072588A2 (pt) 2019-02-19
NZ748959A (en) 2024-02-23
CA3023105A1 (en) 2017-11-09
AU2017259748B2 (en) 2021-08-05
JP7078959B2 (ja) 2022-06-01
ZA201808162B (en) 2021-08-25
SI3470414T1 (sl) 2022-03-31
JP2019519600A (ja) 2019-07-11
AR108369A1 (es) 2018-08-15
MX2018013405A (es) 2019-08-16
US11098039B2 (en) 2021-08-24
SG11201809845TA (en) 2018-12-28
EP3470414A1 (en) 2019-04-17
EA201892461A1 (ru) 2019-04-30
AU2017259748A1 (en) 2018-12-20
WO2017190713A1 (es) 2017-11-09
EP3470414B1 (en) 2021-10-13
KR20210025137A (ko) 2021-03-09
CN110114356B (zh) 2021-09-24
CA3023105C (en) 2023-07-18
BR112018072588B1 (pt) 2024-02-20
KR102428383B1 (ko) 2022-08-02
ES2902992T3 (es) 2022-03-30
CL2018003113A1 (es) 2019-04-12

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