DK3453387T3 - Doseringsplan til en s1p-receptoragonist - Google Patents

Doseringsplan til en s1p-receptoragonist Download PDF

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Publication number
DK3453387T3
DK3453387T3 DK18201062.9T DK18201062T DK3453387T3 DK 3453387 T3 DK3453387 T3 DK 3453387T3 DK 18201062 T DK18201062 T DK 18201062T DK 3453387 T3 DK3453387 T3 DK 3453387T3
Authority
DK
Denmark
Prior art keywords
receptor agonist
dosage plan
dosage
plan
agonist
Prior art date
Application number
DK18201062.9T
Other languages
English (en)
Inventor
Robert Schmouder
Thomas Dumortier
Olivier David
Michael Looby
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41667217&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3453387(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK3453387T3 publication Critical patent/DK3453387T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK18201062.9T 2008-12-22 2009-12-21 Doseringsplan til en s1p-receptoragonist DK3453387T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13967208P 2008-12-22 2008-12-22
US21853009P 2009-06-19 2009-06-19
US24671509P 2009-09-29 2009-09-29
EP16182876.9A EP3120844A1 (en) 2008-12-22 2009-12-21 Dosage regimen for a s1p receptor agonist

Publications (1)

Publication Number Publication Date
DK3453387T3 true DK3453387T3 (da) 2020-08-10

Family

ID=41667217

Family Applications (3)

Application Number Title Priority Date Filing Date
DK18179301.9T DK3409274T3 (da) 2008-12-22 2009-12-21 Doseringsskema for en s1p-receptoragonist
DK18201062.9T DK3453387T3 (da) 2008-12-22 2009-12-21 Doseringsplan til en s1p-receptoragonist
DK09797234.3T DK2379067T3 (da) 2008-12-22 2009-12-21 Doseringsregimen for fingolimod til behandling af multipel sklerose

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK18179301.9T DK3409274T3 (da) 2008-12-22 2009-12-21 Doseringsskema for en s1p-receptoragonist

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK09797234.3T DK2379067T3 (da) 2008-12-22 2009-12-21 Doseringsregimen for fingolimod til behandling af multipel sklerose

Country Status (40)

Country Link
US (11) US20110257133A1 (da)
EP (7) EP3120844A1 (da)
JP (6) JP2012513401A (da)
KR (1) KR101347919B1 (da)
CN (1) CN102264359A (da)
AR (1) AR074826A1 (da)
AU (1) AU2009330176C9 (da)
BR (1) BRPI0923500A2 (da)
CA (1) CA2747802C (da)
CL (2) CL2011001529A1 (da)
CO (1) CO6390117A2 (da)
CR (1) CR20110274A (da)
CU (1) CU20110136A7 (da)
CY (4) CY1116990T1 (da)
DK (3) DK3409274T3 (da)
EA (1) EA201100978A1 (da)
EC (1) ECSP11011222A (da)
ES (3) ES2810823T3 (da)
FR (1) FR20C1060I1 (da)
HN (1) HN2011001759A (da)
HR (3) HRP20151190T1 (da)
HU (4) HUE052048T2 (da)
IL (3) IL213170A0 (da)
LT (3) LT3409274T (da)
MA (1) MA32981B1 (da)
ME (2) ME03802B (da)
MX (2) MX2011006623A (da)
NO (1) NO2020038I1 (da)
NZ (1) NZ593065A (da)
PE (1) PE20120337A1 (da)
PL (3) PL2379067T3 (da)
PT (3) PT3409274T (da)
RS (2) RS60666B1 (da)
SG (1) SG171404A1 (da)
SI (3) SI2379067T1 (da)
TN (1) TN2011000272A1 (da)
TW (1) TW201028143A (da)
UY (1) UY32352A (da)
WO (1) WO2010075239A1 (da)
ZA (2) ZA201103863B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0909625B1 (pt) 2008-03-17 2021-09-08 Actelion Pharmaceuticals Ltd Agonista seletivo do receptor s1p1 para o uso como um medicamento, uso de um agonista seletivo do receptor s1p1 e kit contendo diferentes unidades de medicação de um agonista seletivo do receptor s1p1
BRPI0923500A2 (pt) 2008-12-22 2018-05-29 Novartis Ag uso e composição farmacêutica compreendendo agonista ou modulador do receptor s1p, e kit.
EP2482810A2 (en) 2009-09-29 2012-08-08 Novartis AG Dosage regimen of an s1p receptor modulator
US20110124605A1 (en) * 2009-11-20 2011-05-26 Shreeram Aradhye Use of an S1P Receptor Agonist
EP4148045A1 (en) 2010-01-27 2023-03-15 Arena Pharmaceuticals, Inc. Intermediate compounds for the preparation of (r)-2-(7-(4-cyclopentyl-3- (trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b] indol-3-yl)acetic acid and salts thereof
JP2013525469A (ja) * 2010-05-06 2013-06-20 ノバルティス アーゲー ジアリールスルフィド誘導体の投与レジメン
EP2455080A1 (en) * 2010-11-23 2012-05-23 Almirall, S.A. S1P1 receptor agonists for use in the treatment of multiple sclerosis
FR2968556B1 (fr) 2010-12-13 2013-12-27 Centre Nat Rech Scient Inhibiteurs des infections a vih et leurs utilisations
EP3502236B1 (en) * 2011-02-18 2023-08-23 The Scripps Research Institute Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
JO3177B1 (ar) 2011-04-01 2018-03-08 Novartis Ag تركيبات تتالف من 2-أمينو-2- [ 2- ( 4- أكتيل فينيل ) إثيل ] بروبان - 3, 1- ديول
US9592268B2 (en) 2011-05-23 2017-03-14 Cornell University Endothelium protective materials and methods of use
TW201320994A (zh) 2011-10-11 2013-06-01 Novartis Ag 投藥療程
RS60408B1 (sr) 2012-08-17 2020-07-31 Actelion Pharmaceuticals Ltd Postupak za pripremanje (2z,5z)-5-(3-hloro-4-((r)-2,3-dihidroksipropoksi)benziliden)-2-(propilimino)-3-(o-tolil)tiazolidin-4-ona i međujedinjenja upotrebljena u pomenutom postupku
CA2904055A1 (en) * 2013-03-06 2014-09-12 Acorda Therapeutics, Inc. Therapeutic dosing of a neuregulin or a fragment thereof for treatment or prophylaxis of heart failure
WO2015053879A1 (en) 2013-10-11 2015-04-16 Teikoku Pharma Usa, Inc. Sphingosine-1-phosphate receptor agonist iontophoretic devices and methods of using the same
CN105611917A (zh) 2013-10-11 2016-05-25 帝国制药美国公司 局部鞘氨醇-1-磷酸酯受体激动剂制剂及其使用方法
IL305337A (en) * 2014-04-10 2023-10-01 Novartis Ag A therapeutic regimen containing an immediate release dose of an S1P modulator
EP3256125B1 (en) 2014-12-11 2022-01-26 Actelion Pharmaceuticals Ltd Dosing regimen for ponesimod, a selective s1p1 receptor agonist
AU2016205361C1 (en) * 2015-01-06 2021-04-08 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
WO2016135644A1 (en) 2015-02-26 2016-09-01 Novartis Ag Treatment of autoimmune disease in a patient receiving additionally a beta-blocker
IL285890B (en) 2015-06-22 2022-07-01 Arena Pharm Inc Slate-free crystal of the arginine salt of (Ar)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-4,3,2,1-tetrahydro-cyclopent[b]indole-3-yl ) acetic acid
US11534424B2 (en) 2017-02-16 2022-12-27 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
US11478448B2 (en) 2017-02-16 2022-10-25 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations
AU2020372647A1 (en) 2019-10-31 2022-06-16 Idorsia Pharmaceuticals Ltd Combination of a CXCR7 antagonist with an S1P1 receptor modulator
WO2021158838A1 (en) 2020-02-07 2021-08-12 Argentum Pharmaceuticals Llc Dosage regimen of an s1p receptor modulator
WO2021158848A1 (en) * 2020-02-07 2021-08-12 Argentum Pharmaceuticals Llc Dosage regimen of an s1p receptor agonist
CN113332435B (zh) * 2021-06-18 2022-10-18 广州中医药大学(广州中医药研究院) 鞘氨醇-1-磷酸4受体激动剂及其与真武汤联合在制备治疗慢性肾小球肾炎药物中的应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2126658T3 (es) 1992-10-21 1999-04-01 Yoshitomi Pharmaceutical Compuesto de 2-amino-1,3-propanodiol e inmunosupresor.
JP2004507552A (ja) 2000-08-31 2004-03-11 メルク　エンド　カムパニー　インコーポレーテッド 免疫調節剤としてのリン酸誘導体
MXPA04011384A (es) 2002-05-16 2005-02-14 Novartis Ag Uso de agentes de union del receptor edg en cancer.
EP1663188B1 (en) * 2003-09-12 2016-08-10 Newron Sweden AB Treatment of disorders of the nervous system
US20060002999A1 (en) * 2004-06-17 2006-01-05 Forest Laboratories, Inc. Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane
BRPI0518674A2 (pt) * 2004-11-29 2008-12-02 Novartis Ag regime de dosagem de um agonista de receptor s1p
EP1688141A1 (en) * 2005-01-31 2006-08-09 elbion AG The use of flupirtine for the treatment of overactive bladder and associated diseases, and for the treatment of irritable bowel syndrome
JP2008537493A (ja) * 2005-02-10 2008-09-18 ジー．アイ． ビュー リミティド ガイド要素を有する胃腸用器具の進行技術
AU2008310846C1 (en) * 2007-10-12 2022-10-06 Novartis Ag Compositions comprising sphingosine 1 phosphate (S1P) receptor modulators
BRPI0909625B1 (pt) 2008-03-17 2021-09-08 Actelion Pharmaceuticals Ltd Agonista seletivo do receptor s1p1 para o uso como um medicamento, uso de um agonista seletivo do receptor s1p1 e kit contendo diferentes unidades de medicação de um agonista seletivo do receptor s1p1
WO2009155475A1 (en) * 2008-06-20 2009-12-23 Novartis Ag Paediatric compositions for treating1 multiple sclerosis
BRPI0923500A2 (pt) 2008-12-22 2018-05-29 Novartis Ag uso e composição farmacêutica compreendendo agonista ou modulador do receptor s1p, e kit.
CA2747992C (en) * 2008-12-22 2017-11-07 Novartis Ag Dosage regimen of an s1p receptor agonist

Also Published As

Publication number Publication date
AU2009330176C1 (en) 2016-12-08
AU2009330176C9 (en) 2017-01-05
TN2011000272A1 (en) 2012-12-17
FR20C1060I1 (fr) 2020-12-25
EP4098256A1 (en) 2022-12-07
ES2810823T3 (es) 2021-03-09
UY32352A (es) 2010-07-30
CA2747802A1 (en) 2010-07-01
EP3409274A1 (en) 2018-12-05
SI2379067T1 (sl) 2016-01-29
MX2021010759A (es) 2022-07-19
US20200330407A1 (en) 2020-10-22
CY2020036I1 (el) 2021-03-12
CA2747802C (en) 2021-02-09
PL2379067T3 (pl) 2016-02-29
US20100160259A1 (en) 2010-06-24
LT3453387T (lt) 2020-08-25
HN2011001759A (es) 2013-11-26
KR101347919B1 (ko) 2014-01-07
EP2379067B1 (en) 2015-09-02
SI3409274T1 (sl) 2020-03-31
LT3409274T (lt) 2020-02-10
US20220142949A1 (en) 2022-05-12
MA32981B1 (fr) 2012-01-02
ME03594B (me) 2020-07-20
CO6390117A2 (es) 2012-02-29
DK3409274T3 (da) 2019-12-16
JP2012513401A (ja) 2012-06-14
EP3409274B1 (en) 2019-11-20
HRP20192175T1 (hr) 2020-03-20
JP7329965B2 (ja) 2023-08-21
HUS2000046I1 (hu) 2020-12-28
RS60666B1 (sr) 2020-09-30
HRP20151190T1 (hr) 2016-01-01
WO2010075239A1 (en) 2010-07-01
CY1123255T1 (el) 2021-10-29
RS59857B1 (sr) 2020-02-28
ES2760607T3 (es) 2020-05-14
IL278914A (en) 2021-01-31
LTPA2020005I1 (lt) 2020-12-10
JP2017141238A (ja) 2017-08-17
EP3677260A1 (en) 2020-07-08
US20160263061A1 (en) 2016-09-15
CN102264359A (zh) 2011-11-30
CR20110274A (es) 2011-07-19
PL3453387T3 (pl) 2020-11-02
PT3409274T (pt) 2019-12-17
HUE048717T4 (hu) 2022-02-28
KR20110096175A (ko) 2011-08-29
AU2009330176B2 (en) 2014-03-06
ECSP11011222A (es) 2011-08-31
NZ593065A (en) 2012-11-30
NO2020038I1 (no) 2020-11-18
ZA201205942B (en) 2013-03-27
AU2009330176A1 (en) 2011-07-07
JP2022103194A (ja) 2022-07-07
JP2014144970A (ja) 2014-08-14
EP3453387A1 (en) 2019-03-13
MX2011006623A (es) 2011-07-12
SI3453387T1 (sl) 2020-10-30
US20160081949A1 (en) 2016-03-24
US20140148415A1 (en) 2014-05-29
AR074826A1 (es) 2011-02-16
CU20110136A7 (es) 2012-01-31
CL2011001529A1 (es) 2012-02-24
US20140066657A1 (en) 2014-03-06
HRP20201167T1 (hr) 2020-12-11
CY2020036I2 (el) 2021-06-25
US20170189353A1 (en) 2017-07-06
IL274756A (en) 2020-07-30
HUE026869T2 (en) 2016-08-29
PT2379067E (pt) 2015-12-23
EP2907511A1 (en) 2015-08-19
BRPI0923500A2 (pt) 2018-05-29
CY1116990T1 (el) 2017-04-05
IL213170A0 (en) 2011-07-31
EP2379067A1 (en) 2011-10-26
US20110257133A1 (en) 2011-10-20
PT3453387T (pt) 2020-08-11
US20180289638A1 (en) 2018-10-11
JP2019167360A (ja) 2019-10-03
ES2552823T3 (es) 2015-12-02
TW201028143A (en) 2010-08-01
JP2016135752A (ja) 2016-07-28
EA201100978A1 (ru) 2012-01-30
EP3453387B1 (en) 2020-06-03
HUE048717T2 (hu) 2020-08-28
SG171404A1 (en) 2011-07-28
CL2013001558A1 (es) 2013-10-25
US20190091180A1 (en) 2019-03-28
ME03802B (me) 2021-04-20
CY1122812T1 (el) 2021-05-05
PL3409274T3 (pl) 2020-06-01
PE20120337A1 (es) 2012-04-24
HUE052048T2 (hu) 2021-04-28
ZA201103863B (en) 2012-10-31
EP3120844A1 (en) 2017-01-25
DK2379067T3 (da) 2015-12-07

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