DK328580A - Glycolipider og deres anvendelse som immunologiske adjuvanser - Google Patents

Glycolipider og deres anvendelse som immunologiske adjuvanser

Info

Publication number
DK328580A
DK328580A DK328580A DK328580A DK328580A DK 328580 A DK328580 A DK 328580A DK 328580 A DK328580 A DK 328580A DK 328580 A DK328580 A DK 328580A DK 328580 A DK328580 A DK 328580A
Authority
DK
Denmark
Prior art keywords
adjvants
glycolipides
immunological
immunological adjvants
Prior art date
Application number
DK328580A
Other languages
English (en)
Inventor
M M Ponpipom
T Y Shen
R L Bugianesi
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK328580A publication Critical patent/DK328580A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/14Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/093Preparation of halogenated hydrocarbons by replacement by halogens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18Acyclic radicals, substituted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J17/005Glycosides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK328580A 1979-07-31 1980-07-30 Glycolipider og deres anvendelse som immunologiske adjuvanser DK328580A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/062,586 US4259324A (en) 1979-07-31 1979-07-31 Immunologic adjuvant thio glycoside compounds and compositions

Publications (1)

Publication Number Publication Date
DK328580A true DK328580A (da) 1981-02-01

Family

ID=22043455

Family Applications (1)

Application Number Title Priority Date Filing Date
DK328580A DK328580A (da) 1979-07-31 1980-07-30 Glycolipider og deres anvendelse som immunologiske adjuvanser

Country Status (9)

Country Link
US (1) US4259324A (da)
EP (1) EP0023865A3 (da)
JP (1) JPS5653698A (da)
AU (1) AU6091280A (da)
CA (1) CA1159820A (da)
DK (1) DK328580A (da)
ES (1) ES493846A0 (da)
GR (1) GR69627B (da)
PT (1) PT71624B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431638A (en) * 1982-10-25 1984-02-14 American Cyanamid Company Poly-cation salts of bis(or tris)[4-0-monohexose-thio]-arylene sulfate derivatives
US4435387A (en) 1982-10-25 1984-03-06 American Cyanamid Company Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives
US4652637A (en) * 1985-11-25 1987-03-24 Merck & Co., Inc. Steroidal glycolipids
EP0224173B1 (en) 1985-11-25 1993-04-28 Merck & Co. Inc. Steroidal glycolipids as host resistance stimulators
US4652553A (en) * 1985-11-25 1987-03-24 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators
US4942154A (en) * 1987-06-18 1990-07-17 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators against viral infection
US5019568A (en) * 1987-06-18 1991-05-28 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators against viral infection
US4970199A (en) * 1987-06-18 1990-11-13 Merck & Co., Inc. Steroidal glycolipids as host resistance stimulators against viral infection
US5055562A (en) * 1988-02-01 1991-10-08 Biomira, Inc. Fluorocarbon chain-containing antigenic conjugates
US5695738A (en) * 1995-06-15 1997-12-09 Glycomed Incorporated Steroidal C-glycosides
WO1998009650A1 (fr) * 1996-09-06 1998-03-12 Mitsubishi Chemical Corporation Preparations vaccinales
JP4532618B2 (ja) * 1999-02-25 2010-08-25 株式会社グライコメディクス 新規糖鎖プライマー
ES2320998T3 (es) * 2003-04-02 2009-06-01 The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services Compuestos que contienen colesterol y su uso como inmunogenos frente a borrelia burgdorferi.
DE102004054545A1 (de) * 2004-09-16 2006-04-06 Max-Delbrück-Centrum für Molekulare Medizin Änderung des Beladungszustandes von MHC-Molekülen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4189471A (en) * 1978-07-11 1980-02-19 Merck & Co., Inc. Immunologic glycolipid adjuvants
US4229441A (en) * 1978-12-01 1980-10-21 Merck & Co., Inc. Immunologic adjuvant

Also Published As

Publication number Publication date
PT71624B (en) 1982-03-17
PT71624A (en) 1980-08-01
US4259324A (en) 1981-03-31
ES8106737A1 (es) 1981-09-01
ES493846A0 (es) 1981-09-01
CA1159820A (en) 1984-01-03
GR69627B (da) 1982-07-06
AU6091280A (en) 1981-02-05
EP0023865A3 (en) 1981-04-08
EP0023865A2 (en) 1981-02-11
JPS5653698A (en) 1981-05-13

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