DK324487D0 - Hidtil ukendte forbindelser - Google Patents

Hidtil ukendte forbindelser

Info

Publication number: DK324487D0
Authority: DK; Denmark
Prior art keywords: unknown relationships; unknown; relationships
Prior art date: 1986-06-27

Application number

DK324487A

Other languages

English (en)

Other versions

DK324487A (da

Inventor

Barry Sidney Orlek

Michael Stewart Hadley

Howard Elliott Rosenberg

Harry John Wadsworth

Original Assignee

Beecham Group Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-06-27

Filing date

1987-06-25

Publication date

1987-06-25

1986-06-27 Priority claimed from GB868615784A external-priority patent/GB8615784D0/en

1986-09-17 Priority claimed from GB868622380A external-priority patent/GB8622380D0/en

1987-06-25 Application filed by Beecham Group Plc filed Critical Beecham Group Plc

1987-06-25 Publication of DK324487D0 publication Critical patent/DK324487D0/da

1987-12-28 Publication of DK324487A publication Critical patent/DK324487A/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK324487A 1986-06-27 1987-06-25 Oxazolderivater DK324487A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB868615784A GB8615784D0 (en)	1986-06-27	1986-06-27	Compounds
GB868622380A GB8622380D0 (en)	1986-09-17	1986-09-17	Compounds

Publications (2)

Publication Number	Publication Date
DK324487D0 true DK324487D0 (da)	1987-06-25
DK324487A DK324487A (da)	1987-12-28

Family

ID=26290965

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK324487A DK324487A (da)	1986-06-27	1987-06-25	Oxazolderivater

Country Status (9)

Country	Link
US (1)	US4968691A (da)
EP (1)	EP0261763B1 (da)
JP (1)	JPH0757753B2 (da)
AU (2)	AU638400B2 (da)
DE (1)	DE3789039T2 (da)
DK (1)	DK324487A (da)
ES (1)	ES2061502T3 (da)
NZ (1)	NZ220841A (da)
PT (1)	PT85174B (da)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8528633D0 (en) *	1985-11-21	1985-12-24	Beecham Group Plc	Compounds
NZ219646A (en) *	1986-03-27	1990-10-26	Merck Sharp & Dohme	Oxadiazole derivatives of azacyclics for treating cns disorders
DE3789039T2 (de) *	1986-06-27	1994-06-09	Beecham Group Plc	Verbrückte bicyclische N-heterocyclische Verbindungen.
ATE133415T1 (de) *	1987-04-15	1996-02-15	Beecham Group Plc	Am brückenkopf substituierte azabicyclenderivate
US5324723A (en) *	1987-09-10	1994-06-28	Merck Sharpe & Dohme Ltd.	Oxazoles and thiazoles for the treatment of senile dementia
NZ226000A (en) *	1987-09-10	1991-06-25	Merck Sharp & Dohme	Oxadiazolyl-azabicycloheptanes and pharmaceutical compositions
NZ225999A (en) *	1987-09-10	1992-04-28	Merck Sharp & Dohme	Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
DE3877470T2 (de) *	1987-09-10	1993-06-24	Merck Sharp & Dohme	Oxazole und thiazole zur behandlung seniler demenz.
US5405853A (en) *	1987-09-10	1995-04-11	Merck Sharpe & Dohme Ltd.	Thiadiazoles useful in the treatment of senile dementia
IL88156A (en) *	1987-11-13	1997-02-18	Novo Nordisk As	Azacyclic compounds their preparation and pharmaceutical compositions containing them
EP0322182A3 (en) *	1987-12-22	1992-01-02	Beecham Group Plc	Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
NZ227841A (en) *	1988-02-12	1991-08-27	Merck Sharp & Dohme	Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions
GB8808433D0 (en) *	1988-04-11	1988-05-11	Merck Sharp & Dohme	Therapeutic agents
AU3301689A (en) *	1988-04-15	1989-10-26	Beecham Group Plc	1-azabicyclo-alkyl derivatives
GB8808926D0 (en) *	1988-04-15	1988-05-18	Beecham Group Plc	Novel compounds
GB8816299D0 (en) *	1988-07-08	1988-08-10	Merck Sharp & Dohme	Therapeutic agents
EP0363085A3 (en)	1988-10-03	1991-03-27	Beecham Group Plc	Novel compounds
CA2000041A1 (en) *	1988-10-13	1990-04-13	Barry S. Orlek	Compounds
GB8830226D0 (en) *	1988-12-23	1989-02-22	Beecham Group Plc	Novel compounds
IT1229491B (it) *	1988-12-28	1991-09-03	Roussel Maestretti S P A Ora R	Derivati della 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro impiego come sostanze medicinali
ATE269330T1 (de) *	1989-04-13	2004-07-15	Beecham Group Plc	Chemische verbindungen
EP0398617A3 (en) *	1989-05-15	1991-11-06	Merck Sharp & Dohme Ltd.	Process for resolving 1-azabicyclo [2.2.1]heptane-3-carboxylates
GB8911080D0 (en) *	1989-05-15	1989-06-28	Merck Sharp & Dohme	Chemical process
EP0402056A3 (en) *	1989-06-06	1991-09-04	Beecham Group p.l.c.	Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
GB8917957D0 (en) *	1989-08-05	1989-09-20	Beecham Group Plc	Novel compounds
DE69026197T2 (de) *	1989-10-07	1997-01-09	Beecham Group Plc	Azabizyklische Verbindungen, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
EP0456310A3 (en) *	1990-05-09	1992-03-04	Merck Sharp & Dohme Ltd.	Enantioselective synthesis of 3-substituted 1-azabicyclo (2.2.1)heptanes
GB9017353D0 (en) *	1990-08-08	1990-09-19	Merck Sharp & Dohme	Chemical process
PT98742A (pt) *	1990-08-24	1992-07-31	Beecham Group Plc	Processo para a preparacao de compostos azabicilicos
GB9019095D0 (en) *	1990-09-01	1990-10-17	Beecham Group Plc	Novel compounds
US5356914A (en) *	1990-10-12	1994-10-18	Beecham Group P.L.C.	1,2,5,6-tetrahydropyridine oxime derivatives
US5124460A (en) *	1991-05-06	1992-06-23	Merck Sharp & Dohme Ltd.	Enantioselective synthesis of 3-substituted 1-azabicyclo (2.2.1)heptanes
EP0619814A1 (en) *	1991-12-31	1994-10-19	Fujisawa Pharmaceutical Co., Ltd.	Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity
SE9201478D0 (sv) *	1992-05-11	1992-05-11	Kabi Pharmacia Ab	Heteroaromatic quinuclidinenes, their use and preparation
SG55072A1 (en) *	1993-08-19	1998-12-21	Novo Nordisk As	Antipsychotic method
US5663182A (en) *	1993-08-19	1997-09-02	Bymaster; Franklin Porter	Antipsychotic method
US5733912A (en) *	1997-02-19	1998-03-31	Abbott Laboratories	7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
AU7639598A (en)	1997-05-29	1998-12-30	H. Lundbeck A/S	Treatment of schizophrenia and psychosis
US20050131051A1 (en) *	2000-08-21	2005-06-16	Shaomeng Wang	2-3-disubstituted quinuclidiness as modulators of monoamine transporters and theraperutic and diagnostic methods based thereon
EP2275095A3 (en) *	2005-08-26	2011-08-17	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation
EP2258358A3 (en)	2005-08-26	2011-09-07	Braincells, Inc.	Neurogenesis with acetylcholinesterase inhibitor
US8031118B2 (en)	2006-06-13	2011-10-04	Kabushiki Kaisha Toshiba	Phase correction apparatus, DVOR apparatus, and phase correction method
AU2007292848A1 (en)	2006-09-08	2008-03-13	Braincells, Inc.	Combinations containing a 4-acylaminopyridine derivative

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2658067A (en) *		1953-11-03		Substituted carbamic acdj esters
US3501471A (en) *	1966-09-21	1970-03-17	American Cyanamid Co	Novel 2,3-heterocyclic fused quinuclidines,and 3-substituted quinuclidine-2-carboxylate derivatives
US3681363A (en) *	1970-08-20	1972-08-01	Univ Temple	Spiro(imidazolidine-4,3{40 -quinuclidine)-2,5-diones
US4038402A (en) *	1974-03-05	1977-07-26	Mikhail Emmanuilovich Kaminka	Method of effecting antihistaminic, antiserotonin and antiallergic actions
SU495310A1 (ru) *	1974-03-05	1975-12-15	Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе	Хинуклидил-3-диарал(гетерил) карбинолы, про вл ющие антигистаминную, антисеротониновую и антиаллергическую активность и способ их получени
US4203990A (en) *	1979-04-30	1980-05-20	G. D. Searle & Co.	Anti-diarrheal 2-substituted quinuclidines
FR2526433B1 (fr) *	1982-05-04	1985-10-18	Pharmuka Lab	Isomeres dextrogyres de derives de l'aza-1 bicyclo (2,2,2) octane, leur procede de preparation et medicaments les contenant
NZ219646A (en) *	1986-03-27	1990-10-26	Merck Sharp & Dohme	Oxadiazole derivatives of azacyclics for treating cns disorders
DE3610977A1 (de) *	1986-04-02	1987-10-08	Weinig Michael Gmbh Co Kg	Vorrichtung zum wechseln von werkzeugen einer bearbeitungsmaschine, vorzugsweise einer holzbearbeitungsmaschine
AU620783B3 (en) *	1986-06-27	1992-01-09	Beecham Group Plc	1,2,4-oxadiazolyl-azabicyclo compounds
DE3789039T2 (de) *	1986-06-27	1994-06-09	Beecham Group Plc	Verbrückte bicyclische N-heterocyclische Verbindungen.
DE3877470T2 (de) *	1987-09-10	1993-06-24	Merck Sharp & Dohme	Oxazole und thiazole zur behandlung seniler demenz.
IL88156A (en) *	1987-11-13	1997-02-18	Novo Nordisk As	Azacyclic compounds their preparation and pharmaceutical compositions containing them

1987
- 1987-06-23 DE DE3789039T patent/DE3789039T2/de not_active Expired - Fee Related
- 1987-06-23 ES ES87305586T patent/ES2061502T3/es not_active Expired - Lifetime
- 1987-06-23 EP EP87305586A patent/EP0261763B1/en not_active Expired - Lifetime
- 1987-06-25 NZ NZ220841A patent/NZ220841A/xx unknown
- 1987-06-25 DK DK324487A patent/DK324487A/da unknown
- 1987-06-25 AU AU74695/87A patent/AU638400B2/en not_active Ceased
- 1987-06-25 PT PT85174A patent/PT85174B/pt not_active IP Right Cessation
- 1987-06-26 JP JP62159482A patent/JPH0757753B2/ja not_active Expired - Lifetime
1989
- 1989-03-07 US US07/320,707 patent/US4968691A/en not_active Expired - Fee Related
1991
- 1991-02-22 AU AU71318/91A patent/AU620307B3/en not_active Ceased

Also Published As

Publication number	Publication date
JPH0757753B2 (ja)	1995-06-21
US4968691A (en)	1990-11-06
PT85174B (pt)	1990-03-30
ES2061502T3 (es)	1994-12-16
AU7469587A (en)	1988-01-07
PT85174A (en)	1987-07-01
DK324487A (da)	1987-12-28
JPS6339876A (ja)	1988-02-20
AU638400B2 (en)	1993-07-01
DE3789039D1 (de)	1994-03-24
EP0261763A1 (en)	1988-03-30
AU7131891A (da)	1991-05-23
NZ220841A (en)	1990-08-28
DE3789039T2 (de)	1994-06-09
AU620307B3 (en)	1991-12-17
EP0261763B1 (en)	1994-02-09

Publication	Publication Date	Title
DK324487D0 (da)	1987-06-25	Hidtil ukendte forbindelser
DK17787D0 (da)	1987-01-14	Hidtil ukendte forbindelser
DK191186D0 (da)	1986-04-24	Hidtil ukendte forbindelser
DK483787D0 (da)	1987-09-15	Hidtil ukendte forbindelser
DK709288D0 (da)	1988-12-20	Hidtil ukendte forbindelser
DK691488D0 (da)	1988-12-12	Hidtil ukendte forbindelser
DK681287A (da)	1988-06-25	Hidtil ukendte forbindelser
DK165787D0 (da)	1987-04-01	Hidtil ukendte forbindelser
DK165687D0 (da)	1987-04-01	Hidtil ukendte forbindelser
DK324387D0 (da)	1987-06-25	Hidtil ukendte forbindelser
DK220588A (da)	1988-10-26	Hidtil ukendte forbindelser
DK321088D0 (da)	1988-06-13	Hidtil ukendte forbindelser
DK625086D0 (da)	1986-12-22	Hidtil ukendte forbindelser
DK9987D0 (da)	1987-01-09	Hidtil ukendte forbindelser
DK177889A (da)	1989-10-16	Hidtil ukendte forbindelser
DK227487D0 (da)	1987-05-04	Hidtil ukendte forbindelser
DK90686A (da)	1986-09-02	Hidtil ukendte forbindelser
DK380886D0 (da)	1986-08-08	Hidtil ukendte forbindelser
DK165987D0 (da)	1987-04-01	Hidtil ukendte forbindelser
DK346786D0 (da)	1986-07-21	Hidtil ukendte forbindelser
DK546187A (da)	1988-04-22	Hidtil ukendte forbindelser
DK575286A (da)	1987-05-31	Hidtil ukendte forbindelser
DK340886D0 (da)	1986-07-17	Hidtil ukendte forbindelser
DK448587D0 (da)	1987-08-27	Hidtil ukendte forbindelser
DK359888D0 (da)	1988-06-29	Hidtil ukendte forbindelser