DK3087083T3 - Systemisk opdagelse, modning og forlængelse af peptidbindere til proteiner - Google Patents
Systemisk opdagelse, modning og forlængelse af peptidbindere til proteiner Download PDFInfo
- Publication number
- DK3087083T3 DK3087083T3 DK14821163.4T DK14821163T DK3087083T3 DK 3087083 T3 DK3087083 T3 DK 3087083T3 DK 14821163 T DK14821163 T DK 14821163T DK 3087083 T3 DK3087083 T3 DK 3087083T3
- Authority
- DK
- Denmark
- Prior art keywords
- maturation
- proteins
- extension
- peptide binders
- systemic
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/36—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Actinomyces; from Streptomyces (G)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361921263P | 2013-12-27 | 2013-12-27 | |
US201361921259P | 2013-12-27 | 2013-12-27 | |
PCT/EP2014/078658 WO2015097077A2 (en) | 2013-12-27 | 2014-12-19 | Systemic discovery, maturation and extension of peptide binders to proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3087083T3 true DK3087083T3 (da) | 2019-12-16 |
Family
ID=52273134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14821163.4T DK3087083T3 (da) | 2013-12-27 | 2014-12-19 | Systemisk opdagelse, modning og forlængelse af peptidbindere til proteiner |
Country Status (5)
Country | Link |
---|---|
US (2) | US10161938B2 (da) |
EP (1) | EP3087083B1 (da) |
JP (1) | JP6312225B2 (da) |
DK (1) | DK3087083T3 (da) |
WO (1) | WO2015097077A2 (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016100735A1 (en) | 2014-12-19 | 2016-06-23 | Roche Nimblegen, Inc. | Microbial transglutaminases, substrates therefor and methods for the use thereof |
JP2018513166A (ja) * | 2015-04-20 | 2018-05-24 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 系統的な探索、成熟化および伸長プロセスにより同定した、タンパク質に対する特異的ペプチドバインダー |
US10641778B2 (en) | 2015-08-25 | 2020-05-05 | Roche Sequencing Solutions, Inc. | System and method for analysis of peptide synthesis fidelity |
US10427126B2 (en) * | 2015-10-28 | 2019-10-01 | Roche Sequencing Solutions, Inc. | System and method for longitudinal analysis of peptide synthesis |
CA3006617A1 (en) * | 2015-11-30 | 2017-06-08 | F. Hoffmann-La Roche Ag | System and method for identification of protease substrates |
EP3497446B1 (en) | 2016-08-15 | 2021-04-28 | F. Hoffmann-La Roche AG | Method and composition for detection of peptide cyclization using protein tags |
JP6872024B2 (ja) | 2016-10-04 | 2021-05-19 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 合成分類指標の同定のためのシステムおよび方法 |
JP2020514746A (ja) | 2016-12-01 | 2020-05-21 | ノーティラス バイオテクノロジー インコーポレイテッド | タンパク質をアッセイする方法 |
WO2018165328A1 (en) * | 2017-03-07 | 2018-09-13 | Recombipure, Inc. | Compositions, methods, and systems for affinity-based protein identification and purification |
CN111566261A (zh) * | 2017-08-18 | 2020-08-21 | 诺迪勒思生物科技公司 | 选择结合试剂的方法 |
EP3775196A4 (en) | 2018-04-04 | 2021-12-22 | Nautilus Biotechnology, Inc. | NANOREWAL AND MICROREWAL GENERATION PROCESSES |
JP2022512761A (ja) * | 2018-10-22 | 2022-02-07 | エフ.ホフマン-ラ ロシュ アーゲー | 関節リウマチ自己抗体レパートリーのプロファイリング及びそのためのペプチド分類子 |
US11993865B2 (en) | 2018-11-20 | 2024-05-28 | Nautilus Subsidiary, Inc. | Selection of affinity reagents |
JP2022538433A (ja) | 2019-06-27 | 2022-09-02 | ロシュ シークエンシング ソリューションズ,インコーポレイティド | 増強された部分配列多様性を有するペプチドライブラリ及びその使用方法 |
CN116096405A (zh) * | 2020-05-12 | 2023-05-09 | Cue生物制药股份有限公司 | 多聚体t细胞调节多肽及其使用方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ299048A (en) | 1992-03-06 | 1998-09-24 | Innogenetics Sa Nv | Modified peptides corresponding to immunologically useful epitopes in hiv, hcv and htlv and their use especially when biotinylated |
EP0772773B1 (en) | 1994-07-22 | 2006-04-05 | The University Of North Carolina | Src SH3 BINDING PEPTIDES AND METHODS OF ISOLATING AND USING SAME |
DK0868427T3 (da) * | 1995-12-18 | 2003-09-15 | Praecis Pharm Inc | Fremgangsmåder til at idenficere forbindelser, der binder til et mål |
EP1197755A1 (en) * | 2000-10-11 | 2002-04-17 | Pepscan Systems B.V. | Identification of protein binding sites |
DE60223922T2 (de) * | 2001-05-07 | 2008-11-27 | Hipep Laboratories | Peptidimmobilisierte grundplatte und verfahren zum testen eines zielproteins unter verwendung derselben |
US20050267020A1 (en) | 2001-09-27 | 2005-12-01 | Olivier Faure | Polypeptides derived from inducible hsp70 and pharmaceutical compositions containing the same |
EP1576172A2 (en) | 2002-06-21 | 2005-09-21 | Dyax Corporation | Serum protein-associated target-specific ligands and identification method therefor |
US20040018886A1 (en) | 2002-07-24 | 2004-01-29 | Burrows Bruce D. | Temporary golf club shaft-component connection |
MXPA06002311A (es) | 2003-09-05 | 2006-05-19 | Genencor Int | Epitopos de celulas t cd8+ del virus del papiloma humano (vph). |
JP2007527539A (ja) * | 2004-03-05 | 2007-09-27 | ザ スクリプス リサーチ インスティテュート | ハイスループットグリカンマイクロアレイ |
WO2010052939A1 (ja) | 2008-11-10 | 2010-05-14 | 国立大学法人名古屋大学 | アレルゲンのエピトープ又はその候補の検出方法及びその利用 |
WO2013119845A1 (en) * | 2012-02-07 | 2013-08-15 | Vibrant Holdings, Llc | Substrates, peptide arrays, and methods |
JP5495457B1 (ja) | 2013-08-30 | 2014-05-21 | 東レバッテリーセパレータフィルム株式会社 | 電池用セパレータ及びその電池用セパレータの製造方法 |
-
2014
- 2014-12-19 WO PCT/EP2014/078658 patent/WO2015097077A2/en active Application Filing
- 2014-12-19 US US14/577,334 patent/US10161938B2/en active Active
- 2014-12-19 EP EP14821163.4A patent/EP3087083B1/en active Active
- 2014-12-19 JP JP2016541379A patent/JP6312225B2/ja active Active
- 2014-12-19 DK DK14821163.4T patent/DK3087083T3/da active
-
2018
- 2018-11-14 US US16/191,407 patent/US10976317B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP3087083B1 (en) | 2019-10-16 |
JP6312225B2 (ja) | 2018-04-18 |
US20190086411A1 (en) | 2019-03-21 |
JP2017504795A (ja) | 2017-02-09 |
WO2015097077A3 (en) | 2015-08-13 |
EP3087083A2 (en) | 2016-11-02 |
US10976317B2 (en) | 2021-04-13 |
WO2015097077A2 (en) | 2015-07-02 |
US10161938B2 (en) | 2018-12-25 |
US20150185216A1 (en) | 2015-07-02 |
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