DK3041926T3 - Indretning til in-vitro-modellering af in-vivo-væv af organer - Google Patents

Indretning til in-vitro-modellering af in-vivo-væv af organer Download PDF

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Publication number
DK3041926T3
DK3041926T3 DK14758977.4T DK14758977T DK3041926T3 DK 3041926 T3 DK3041926 T3 DK 3041926T3 DK 14758977 T DK14758977 T DK 14758977T DK 3041926 T3 DK3041926 T3 DK 3041926T3
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DK
Denmark
Prior art keywords
bodies
vivo tissue
vitro modeling
modeling
vitro
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Application number
DK14758977.4T
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English (en)
Inventor
Olivier Thierry Guenat
Marcel Felder
Andreas Stucki
Janick Daniel Stucki
Thomas Geiser
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Univ Bern
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Publication of DK3041926T3 publication Critical patent/DK3041926T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02Membranes; Filters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02Membranes; Filters
    • C12M25/04Membranes; Filters in combination with well or multiwell plates, i.e. culture inserts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10Perfusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/08Chemical, biochemical or biological means, e.g. plasma jet, co-culture
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK14758977.4T 2013-09-05 2014-09-05 Indretning til in-vitro-modellering af in-vivo-væv af organer DK3041926T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13183063 2013-09-05
PCT/EP2014/068921 WO2015032889A1 (en) 2013-09-05 2014-09-05 Device for in-vitro modelling in-vivo tissues of organs

Publications (1)

Publication Number Publication Date
DK3041926T3 true DK3041926T3 (da) 2020-06-08

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Family Applications (1)

Application Number Title Priority Date Filing Date
DK14758977.4T DK3041926T3 (da) 2013-09-05 2014-09-05 Indretning til in-vitro-modellering af in-vivo-væv af organer

Country Status (8)

Country Link
US (3) US10066198B2 (da)
EP (2) EP3663388A1 (da)
CN (2) CN114134042A (da)
DK (1) DK3041926T3 (da)
ES (1) ES2795974T3 (da)
PL (1) PL3041926T3 (da)
PT (1) PT3041926T (da)
WO (1) WO2015032889A1 (da)

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ES2615512B1 (es) * 2015-11-06 2018-03-15 Universidad De Zaragoza Dispositivo y sistema microfluídico para el estudio de cultivos celulares
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CN109804057B (zh) * 2016-06-15 2022-09-09 米梅塔斯私人有限公司 细胞培养装置以及细胞培养方法
WO2018098169A1 (en) 2016-11-23 2018-05-31 The Charles Stark Draper Laboratory, Inc. Bi-layer multi-well cell culture platform
KR20230019986A (ko) * 2016-11-24 2023-02-09 알베오릭스 테크놀러지스 아게 세포 배양 시스템 및 방법
CN106929403A (zh) * 2017-04-14 2017-07-07 西安医学院 一种用于药物高通量筛选的血脑屏障模拟装置
JP7195302B2 (ja) 2017-07-14 2022-12-23 コーニング インコーポレイテッド 3d培養のための細胞培養容器及び3d細胞の培養方法
US11857970B2 (en) 2017-07-14 2024-01-02 Corning Incorporated Cell culture vessel
EP3652290B1 (en) 2017-07-14 2022-05-04 Corning Incorporated 3d cell culture vessels for manual or automatic media exchange
CN111065729B (zh) 2017-07-14 2024-04-26 康宁股份有限公司 细胞培养容器
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CN111032851B (zh) 2018-07-13 2024-03-29 康宁股份有限公司 具有包含液体介质传递表面的侧壁的微腔皿
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US11007524B2 (en) * 2019-01-18 2021-05-18 National Tsing Hua University Automatic microfluidic system for rapid personalized drug screening and testing method for personalized antibiotic susceptibility
CN113728086A (zh) 2019-03-26 2021-11-30 株式会社村田制作所 微生物培养装置及微生物培养方法
US20210340477A1 (en) * 2020-05-01 2021-11-04 The Charles Stark Draper Laboratory Inc. Microfluidic cell culture plate for air-liquid interface and 3d cultured tissue applications
CN112080425A (zh) * 2020-09-07 2020-12-15 中国科学院上海微***与信息技术研究所 一种器官芯片、上皮/内皮屏障模型器件及其制作方法
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Also Published As

Publication number Publication date
CN105593358B (zh) 2021-12-21
US20160194588A1 (en) 2016-07-07
PL3041926T3 (pl) 2020-11-02
US20230015127A1 (en) 2023-01-19
CN105593358A (zh) 2016-05-18
EP3663388A1 (en) 2020-06-10
EP3041926B1 (en) 2020-03-04
EP3041926A1 (en) 2016-07-13
PT3041926T (pt) 2020-06-17
ES2795974T3 (es) 2020-11-25
US20180355299A1 (en) 2018-12-13
WO2015032889A1 (en) 2015-03-12
US11473045B2 (en) 2022-10-18
CN114134042A (zh) 2022-03-04
US10066198B2 (en) 2018-09-04

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