DK2799090T4 - Fremgangsmåde til fremstilling af en farmaceutisk kontrastmiddelformulering - Google Patents

Fremgangsmåde til fremstilling af en farmaceutisk kontrastmiddelformulering Download PDF

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Publication number
DK2799090T4
DK2799090T4 DK14165008.5T DK14165008T DK2799090T4 DK 2799090 T4 DK2799090 T4 DK 2799090T4 DK 14165008 T DK14165008 T DK 14165008T DK 2799090 T4 DK2799090 T4 DK 2799090T4
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DK
Denmark
Prior art keywords
contractive
formulation
pharmaceutical
preparing
procedure
Prior art date
Application number
DK14165008.5T
Other languages
English (en)
Other versions
DK2799090T5 (da
DK2799090T3 (da
Inventor
Dominique Meyer
Claire Corot
Marc Port
Bruno Bonnemain
Vincent Barbotin
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40955314&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2799090(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR0851055A external-priority patent/FR2927539B1/fr
Application filed by Guerbet Sa filed Critical Guerbet Sa
Application granted granted Critical
Publication of DK2799090T3 publication Critical patent/DK2799090T3/da
Publication of DK2799090T5 publication Critical patent/DK2799090T5/da
Publication of DK2799090T4 publication Critical patent/DK2799090T4/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A61K49/108—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA the metal complex being Gd-DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK14165008.5T 2008-02-19 2009-02-18 Fremgangsmåde til fremstilling af en farmaceutisk kontrastmiddelformulering DK2799090T4 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR0851055A FR2927539B1 (fr) 2008-02-19 2008-02-19 Procede de preparation d'une formulation pharmaceutique d'agents de contraste.
EP08154745 2008-04-17
US12/155,997 US20090208421A1 (en) 2008-02-19 2008-06-12 Process for preparing a pharmaceutical formulation of contrast agents
EP13154448.8A EP2591807A1 (en) 2008-02-19 2009-02-18 Process for preparing a pharmaceutical formulation of contrast agents

Publications (3)

Publication Number Publication Date
DK2799090T3 DK2799090T3 (da) 2016-10-03
DK2799090T5 DK2799090T5 (da) 2017-04-18
DK2799090T4 true DK2799090T4 (da) 2020-05-18

Family

ID=40955314

Family Applications (3)

Application Number Title Priority Date Filing Date
DK14165006.9T DK2799089T3 (da) 2008-02-19 2009-02-18 Fremgangsmåde til fremstilling af en farmaceutisk kontrastmiddelformulering
DK14165008.5T DK2799090T4 (da) 2008-02-19 2009-02-18 Fremgangsmåde til fremstilling af en farmaceutisk kontrastmiddelformulering
DK09712403.6T DK2242515T3 (da) 2008-02-19 2009-02-18 Fremgangsmåde til fremstilling af en farmaceutisk kontrastmiddelformulering

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK14165006.9T DK2799089T3 (da) 2008-02-19 2009-02-18 Fremgangsmåde til fremstilling af en farmaceutisk kontrastmiddelformulering

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK09712403.6T DK2242515T3 (da) 2008-02-19 2009-02-18 Fremgangsmåde til fremstilling af en farmaceutisk kontrastmiddelformulering

Country Status (17)

Country Link
US (6) US20090208421A1 (da)
EP (6) EP2799090B2 (da)
JP (3) JP5469615B2 (da)
KR (1) KR101063060B1 (da)
CN (1) CN101977633B (da)
BR (1) BRPI0908221B1 (da)
CA (1) CA2714118C (da)
CY (2) CY1115259T1 (da)
DE (1) DE202008010019U1 (da)
DK (3) DK2799089T3 (da)
ES (3) ES2593127T5 (da)
HR (2) HRP20140537T1 (da)
HU (2) HUE031091T2 (da)
LT (2) LT2799090T (da)
PL (3) PL2799089T3 (da)
PT (3) PT2799089T (da)
WO (1) WO2009103744A2 (da)

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US20090208421A1 (en) 2008-02-19 2009-08-20 Dominique Meyer Process for preparing a pharmaceutical formulation of contrast agents
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HUE051988T2 (hu) * 2013-01-07 2021-04-28 Univ Pennsylvania Készítmények és eljárások bõr T-sejt lymphoma kezelésére
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CA2909919C (fr) * 2013-04-26 2022-07-12 Guerbet Formulation de produit de contraste et son procede de preparation associe
KR101466602B1 (ko) * 2013-05-31 2014-12-01 동국제약 주식회사 메글루민 가도테레이트를 포함하는 조영제 조성물의 제조방법
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GB201421163D0 (en) * 2014-11-28 2015-01-14 Ge Healthcare As Formulations of metal complexes
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CN111263747B (zh) 2017-05-05 2023-10-27 探针技术开发及商业化中心 双官能螯合物的药代动力学增强及其用途
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Also Published As

Publication number Publication date
EP2799090B2 (en) 2020-03-04
EP2799090B9 (en) 2016-12-21
DK2799090T5 (da) 2017-04-18
JP2014114306A (ja) 2014-06-26
CY1118985T1 (el) 2018-01-10
CA2714118A1 (en) 2009-08-27
WO2009103744A2 (en) 2009-08-27
US9636427B2 (en) 2017-05-02
ES2477541T3 (es) 2014-07-17
ES2593127T5 (es) 2020-09-25
EP3620179A1 (en) 2020-03-11
US20170189563A1 (en) 2017-07-06
EP2242515B1 (en) 2014-04-02
EP2799089A3 (en) 2015-03-04
DK2799090T3 (da) 2016-10-03
EP2799090B1 (en) 2016-06-29
PL2799090T5 (pl) 2020-07-13
US20160235867A1 (en) 2016-08-18
CN101977633B (zh) 2012-08-29
US9907866B2 (en) 2018-03-06
US20090208421A1 (en) 2009-08-20
ES2593127T9 (es) 2017-05-08
PL2242515T3 (pl) 2014-08-29
EP2799089B9 (en) 2017-09-06
DE202008010019U1 (de) 2009-07-02
DK2242515T3 (da) 2014-07-07
BRPI0908221A2 (pt) 2018-03-20
HUE030219T2 (en) 2017-04-28
LT2799089T (lt) 2016-11-10
US20130336898A1 (en) 2013-12-19
HRP20161312T1 (hr) 2016-12-16
PT2799089T (pt) 2016-10-25
EP3159014A1 (en) 2017-04-26
PT2799090T (pt) 2016-09-28
KR20100133976A (ko) 2010-12-22
EP2242515B9 (en) 2014-10-01
HUE031091T2 (en) 2017-06-28
CA2714118C (en) 2017-03-28
JP2016117778A (ja) 2016-06-30
CY1115259T1 (el) 2017-01-04
PT2242515E (pt) 2014-07-11
EP2799089B1 (en) 2016-08-03
EP2591807A1 (en) 2013-05-15
JP5985523B2 (ja) 2016-09-06
PL2799090T3 (pl) 2017-08-31
US20160235868A1 (en) 2016-08-18
WO2009103744A3 (en) 2009-12-17
EP2799090A3 (en) 2015-01-14
JP2011514334A (ja) 2011-05-06
LT2799090T (lt) 2016-10-10
JP5469615B2 (ja) 2014-04-16
EP2242515A2 (en) 2010-10-27
ES2597782T3 (es) 2017-01-23
ES2593127T3 (es) 2016-12-05
HRP20161312T2 (hr) 2018-01-26
EP2799089A2 (en) 2014-11-05
US9655983B2 (en) 2017-05-23
JP6422460B2 (ja) 2018-11-14
HRP20140537T1 (hr) 2014-07-18
CN101977633A (zh) 2011-02-16
PL2799089T3 (pl) 2017-08-31
KR101063060B1 (ko) 2011-09-07
DK2799089T3 (da) 2016-11-21
US20110129425A1 (en) 2011-06-02
EP2799090A2 (en) 2014-11-05
BRPI0908221B1 (pt) 2021-07-13

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